In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

CREEA is a FP7 project on compiling and refining environmental and economic accounts. The project runs from April 2011 to March 2014.

We verwelkomen gastwetenschappers wier onderzoek aansluit bij onze uiteenlopende expertisegebieden. De tekst gaat verder in het Engels.

Promotor: J.N. Kok, Co-promotor: M.S. Lew

Including modelling as part of software development appears to have various benefits.

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Tijdens de introductieweek is dé start van jouw studentenleven in Leiden. Doe mee aan de EL CID, de OWL of de HOP en leer de stad kennen.

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Promotor: F. Arbab

Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.

Op 17 november 2021 verdedigde Cyril-Igor Grigorieff het proefschrift 'The Regime for International Air Carrier Liability'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof.dr. V. Correia (University Paris Saclay).

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

This thesis addresses the challenge of sustainable urban development by analyzing the interplay between green and grey infrastructure to optimize resource use and ecosystem services.

Antibiotica Gezocht! is een initiatief van medewerkers en studenten van de Universiteit Leiden en het Erasmus Medisch Centrum in Rotterdam. Zij doen onderzoek naar antibiotica en de bacteriën die antibiotica produceren. In 2011 wonnen wij de Academische Jaarprijs met het project Antibiotica Gezocht!…

Indicators to measure progress in de-linking economic growth and environmental pressure.

This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.

Exploring linkages between energy and material use and implications for sustainable development.

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

Promotor: M. Franx, Co-Promotor: I.F. Labbé

Promotor: Prof.dr. M. Ubbink

The thesis addresses the long-term dynamical evolution of hierarchical multiple systems.

Promotores: P. Stevenhagen, L. van Geemen (Università degli studi di Milano), Co-Supervisor: Ronald M. van Luijk

The radio sky harbours both galactic and extragalactic sources of arcminute- to degree-scale emission of various physical origins. To discover extragalactic diffuse emission in the Cosmic Web beyond galaxy clusters, one must image low–surface brightness structures amidst a sea of brighter compact fore-…

Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

What happens to electrical waves that have to cross gaps in insulation material around nerves in the human body

This thesis focuses on addressing four research problems in designing embedded streaming systems.

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

How do you engage society to stop biodiversity loss? How do you create political and social involvement to deal with climate change? And how do you balance the economic needs of industry with the negative effects of pollution? If you find these kinds of questions interesting, then this Pre-University…

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

The Dutch atlas with pesticides concentrations in surface waters have been overhauled. This new, free accessible, website is in line with the European Framework Directive on Water (In Dutch: KRW).

How can we quantify the density of species within a community through environmental DNA concentrations?

Als je werkt in de publieke arena krijg je te maken met vraagstukken waarvoor geen pasklare antwoorden bestaan. Om met deze dilemma’s om te gaan is een geijkt kompas een must.

Applications to the PhD and MPhil are now open at the Australian Catholic University (Melbourne). Applicants must submit their completed application by 11:59pm Sunday 18th October 2020 (AEDT).

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Geesteswetenschappen, Centre for the Arts in Society

Archeologie, World Archaeology

Onder leiding van Artificial Intelligence-experts Marlies van Eck en Ronald van den Hoogen is het multidisciplinaire opleidingsprogramma samengesteld. Dit is de eerste editie van postacademische leergang van het Leidse PAO-bureau en extra bijzonder is dat de leergang volledig online plaatsvindt.

Op 22 november 2018 vond ter ere van het afscheid van prof.dr. Jan van den Berg, hoogleraar Cyber Security en wetenschappelijk directeur van de stichting Cyber Security Academy (CSA) een afscheidsseminar plaats.

Psychologen Janine Westendorp MSc en Dr. Liesbeth van Vliet van de Universiteit Leiden onderzochten wat ernstig zieke patiënten als schadelijke communicatie kunnen ervaren. De resultaten van dit onderzoek zijn reeds gepubliceerd in het Amerikaanse tijdschrift Cancer, maar worden nu ook uitgebracht als…

Development of scenarios for 2050 detailed in an IO framework

Wereldwijd is er een groeiende beweging om universiteitscurricula te dekoloniseren. Zowel onderwijsstaf als studenten zoeken naar manieren om bestaande epistemische hiërarchieën in het hoger onderwijs kritisch te evalueren. Dit onderzoekproject richt zich op het ontrafelen van wat dekoloniseren betekent…

In de bachelor Duitse taal en cultuur verdiep je je in de taal, de literatuur, de cultuur en de geschiedenis. Je maakt kennis met boeken, kranten, blogs en films en leert er onderzoek naar doen. Ook bestudeer je de Duitse taal zelf, in vergelijking met je moedertaal en met andere talen die je spreekt.…