In this thesis we present several methods to automate tomographic reconstruction algorithms and several novel tomographic reconstruction algorithms with the focus on being easily applicable and efficient to use.

With tomography it is possible to reconstruct the interior of an object without destroying.

Promotor: K.J. Batenburg

Promotor: Prof.dr. K.J. Batenburg

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

Tomography is a powerful technique to non-destructively determine the interior structure of an object.Usually, a series of projection images (e.g.\ X-ray images) is acquired from a range of different positions.

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

Promotie

In this work the reconstruction of a tau neutrino signal in the KM3NeT detector is discussed.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele

Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit

The mycorrhizal symbiosis is among the most widespread species interactions on Earth⁠. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries⁠.

On 8 July, the symposium 'The digital reconstruction of the crucifixion of the Lindau master (ca. 1425)' will take place at the auditorium of Museum Catharijnecovent, from where it will also be broadcasted online.

Promotores: R. Tijdeman, K.J. Batenburg

Promotores: K.J. Batenburg, B. Koren

Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg

This thesis surveys the intersection of computed tomography (CT) and machine learning (ML), treating CT as an ill-posed inverse problem shaped by object properties, imaging physics, and data limitations.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Promotores: Prof.dr. J.N. Kok, Prof.dr. C.A. Mandemakers, Co-Promotor: G. Bloothooft

This dissertation investigates how the efficiency of Computed Tomography (CT) can be improved for dynamic scientific and industrial applications.

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Visualizing the internal structure is a crucial step in acquiring knowledge about the origin, state, and composition of cultural heritage artifacts. Among the most powerful techniques for exposing the interior of cultural heritage objects is computed tomography (CT), a technique that computationally…

In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.

Indo-European is the name of the language family to which English belongs, along with many sub-families such as Germanic languages and Romance languages. In this course, you will delve into the structure and origins of these branches, the oldest languages belonging to the language family, linguistic…

Lezing

Taalkundige Marian Klamer, verbonden aan het Leiden University Centre for Linguistics en het Leiden University Institute for Area Studies, is een van de 31 wetenschappers die van het NWO een Vici-subidie gekregen heeft voor haar onderzoeksproject 'Taal als tijdmachine'.

Lezing, Lezingenreeks vergelijkende Indo-Europese taalwetenschap (VIET)

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

Reconstructie van de taalgeschiedenis door onderzoek naar taalverandering.

Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

Promotor: Prof.dr. E. Smets, M. Stech

Promotor: Prof.dr. P.C. van Welzen

Live meekijken met een CT-scan in plaats van achteraf de beelden pas te analyseren. Als het aan de Leidse wiskundige Jan-Willem Buurlage ligt, is dat binnenkort realiteit. Hij ontwikkelt methodes om de algoritmes achter 3D-scans sneller te maken. Best een uitdaging: ‘Net als wiskundigen zijn computers…

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…

Quantum computing represents a fundamentally new computational paradigm, capable of addressing problems that are intractable for classical computers.