Promotores: J.N. Kok, H.J. Hoogeboom

Moet je alles kunnen zeggen op Twitter en Facebook? Is Instagram moreel verplicht foto’s te verwijderen van aanslagen? Moeten we toestaan dat terroristische groepering nieuwe leden werven op het internet?

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Kunst en vrije tijd, Kunst en vrije tijd

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

Promotores: S.F. Portegies Zwart, E. M. Rossi

The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

In our research protein translocation from Agrobacterium into yeast and plant cells is studied to obtain fundamental insights in the translocation process

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

Promotor: Prof.dr. M. de Jong

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Patients share valuable advice and experiences with their peers in online patient discussion groups.

Special Issue in: Visual Anthropology, Volume 29, Issue 3, 2016

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

The intracluster medium (ICM) is a hot, tenuous and X-ray emitting gas that pervades galaxy clusters.

Op 1 juni 2022 verdedigde Tom Herrenberg het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. P.B. Cliteur en prof.dr. B.R. Rijpkema.

Patterned detectors are an existing technology that can be found in almost all color cameras.

In this thesis, I investigated the neurogenetic properties of Neotropical bat species. Bats represent the second largest mammalian order (Chiroptera) in the world, with Neotropical bats constituting about 13% of the total number of bat species.

Natuurlijk is Jan Melissen trots op de publicatie van zijn nieuwe boek. Toch blijft een pijnlijke herinnering hangen: door Amerikaanse inmenging moest hij het hoofdstuk over citizen diplomacy, diversiteit en inclusie noodgedwongen verwijderen. ‘Het heeft wel wat met mij gedaan.’

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

Kunst en vrije tijd, Kunst en vrije tijd

Galaxies form and live inside dark matter haloes. As a consequence, they are exposed to the tidal fields generated by the surrounding matter distribution: this imprints a preferential direction to the galaxy shapes, which leads to a coherent alignment on physically close galaxies, called intrinsic a…

Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel

Promotor: Roeland M.H. Merks

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Workshop

In dit artikel onderzoeken Wout Broekema, Wouter Jong en Sara Perlstein het ontwerp en de beoordeling van crisisonderzoeken vanuit een leerperspectief.

Promotie

Promotor: Ronald Cramer, Co-promotor: Serge Fehr

Hydrocarbonylation of alkenes with carboxylic acids in synthesis of carboxylic acid anhydrides is relatively less explored. We herein present a study and optimization of a palladium-catalyzed hydrocarbonylation reaction of alkenes using carboxylic acids as the nucleophile, by which acid anhydrides can…

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

The class-imbalance problem is a challenging classification task and is frequently encountered in real-world applications. Various techniques have been developed to improve the imbalanced classification performance theoretically and practically.

In this thesis, we study different curved single crystals because of the diversity of surface structures across their curvature.

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

Wat doe je als je iets te weten wilt komen? Tegenwoordig gebruikt men voornamelijk het internet om informatie te verkrijgen. Een lezer moet deze informatie vaak uit meerdere bronnen halen en die bronnen met elkaar in verband brengen, om zo een compleet plaatje te vormen van het onderwerp. Soms is de…

This thesis advances automata learning, a key area in computer science, with applications in software verification, biological analysis, and autonomous technologies. It explores three main themes: first, it introduces a passive learning algorithm for generating compact probabilistic models from positive…