647 zoekresultaten voor “play and media” in de Publieke website
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis thaliana
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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The tension between nature conservation and economic valuation of ecosystem services
Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters
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Cognitive Bias in the Judgment of Business Valuations and Valuators
Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.
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Innovation and stasis
The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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The electrode-electrolyte interface in CO2 reduction and H2 evolution: a multiscale approach
Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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The role of the interleukin 12 family in atherosclerosis
Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager
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Understanding protein complex formation: The role of charge distribution in the encounter complex
Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.
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into the role of ceramide subclass composition on lipid organization and skin barrier
The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.
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K-pop
Kunst en vrije tijd, Kunst en vrije tijd
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Social network and radical innovation: evidence from the U.S. pharmaceutical and biotechnology industry
Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.
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Fundamental research on the voltammetry of polycrystalline gold
Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.
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Innovative sample preparation and handling strategies for automated and high-throughput metabolomics
Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Mattijs Numans
Faculteit Geneeskunde
m.e.numans@lumc.nl | +31 71 526 9111
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Antonius Johannes Rabelink
Faculteit Geneeskunde
a.j.rabelink@lumc.nl | +31 71 526 2148
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Liwen Meng
Faculteit der Sociale Wetenschappen
l.meng@fsw.leidenuniv.nl | +31 71 527 2727
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Peter van der Zwan
Faculteit Rechtsgeleerdheid
p.w.van.der.zwan@law.leidenuniv.nl | +31 71 527 8560
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Peter de Knijff
Faculteit Geneeskunde
p.de_knijff@lumc.nl | +31 71 526 9537
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Susan van den Brink
Wiskunde en Natuurwetenschappen
s.van.den.brink@cml.leidenuniv.nl | +31 71 527 2727
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Nadia Garnefski
Faculteit der Sociale Wetenschappen
garnefski@fsw.leidenuniv.nl | +31 71 527 3774
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Barbara Krakovská
Faculteit Governance and Global Affairs
b.krakovska@fgga.leidenuniv.nl | +31 70 800 9500
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Alies Jansen
Faculteit der Geesteswetenschappen
e.jansen@hum.leidenuniv.nl | +31 71 527 1255
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Abdourahamane Idrissa Abdoulaye
Afrika-Studiecentrum
a.idrissa.abdoulaye@asc.leidenuniv.nl | +31 71 527 3372
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Granular Flows: Fluidization and Anisotropy
Promotor: Prof.dr. M.L. van Hecke
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CIRM interviewt Frank den Hollander
Van 2 t/m 6 juni 2014 heeft Prof. dr. Frank den Hollander 2 voordrachten verzorgd tijdens de workshop ‘Recent Models in Random Media’ op het Centre International de Rencontres Mathematiques in Marseille (CIRM), een instituut dat gedurende het hele jaar workshops voor wiskundigen organiseert.
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Random walks in dynamic random environments
Promotor: W.Th.F. den Hollander
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Zheng Li, Promoting Harmony with Conflicts?
In dit proefschrift wordt gekeken naar de produktie en consumptie van het reality-tv-programma ‘Nieuwe Wijze Oom’. Deze show, uitgezonden op het entertainmentkanaal van de provincie Shanghai, draait om mediation in conflicten tussen burgers. ‘Nieuwe Wijze Oom’ is geliefd bij het publiek én bij de autoriteiten.…
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Adriaan van der Weel over E-READ in Frankfurter Allgemeine Zeitung
Onderzoekers van meer dan 30 landen namen deel in het Europese onderzoeksnetwerk E-READ om de veranderingen in het lezen door digitalisering te bestuderen. Adriaan van der Weel, universitair hoofddocent, sprak over het succes van het netwerk met de Duitse krant Frankfurter Allgemeine Zeitung.
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Weiyan Low
Faculteit der Sociale Wetenschappen
w.low@fsw.leidenuniv.nl | +31 71 527 2727
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Bart Barendregt
Faculteit der Sociale Wetenschappen
barendregt@fsw.leidenuniv.nl | +31 71 527 3475
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Akrati Saxena
Wiskunde en Natuurwetenschappen
a.saxena@liacs.leidenuniv.nl | +31 71 527 2727
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Federico De Musso
Faculteit der Sociale Wetenschappen
f.de.musso@fsw.leidenuniv.nl | +31 71 527 2727
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Florian Schneider
Faculteit der Geesteswetenschappen
f.a.schneider@hum.leidenuniv.nl | +31 71 527 2544
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creatIef, Creatiever, creaTiefst? Onderzoek naar het belang en de werking van creativiteitstraining bij Bachelor ICT-studenten
This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.
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The electrochemical reduction of dioxygen and hydrogen peroxide by molecular copper catalysts
The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…
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AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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The impact of defense hormones on the interaction between plants and the soil microbial community
The soil ecosystem consists of the largest reservoir of biodiversity on Earth.
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Data-Driven Risk Assessment in Infrastructure Networks
Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Hydrodynamics and the quantum butterfly effect in Black Holes and large N quantum field theories
Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?
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CO2 reduction toward liquid fuels : on heterogeneous electrocatalysts and heterogenized molecular catalysts
With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.
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Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
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dimension of environmental Life Cycle Assessment: addressing choice, future and interpretation uncertainties.
LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.
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Bakti and Sayan traditions among the Tenggerese people in East Java: the role of indigenous institutions in integrated elderly care development
This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…