1,098 zoekresultaten voor “leiden research support network” in de Publieke website
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Chemical tools to modulate endocannabinoid biosynthesis
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Exploring the Edge
At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Carrièreperspectieven
In een politicologische masterspecialisatie leer je op een sociaal-wetenschappelijke manier te analyseren. Daarnaast doe scherp je allerhande praktische vaardigheden aan. Daarmee kun jij een verschil maken in de wereld van beleid, bestuur....
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NanoFeed
Do selenium nanoparticles in fish food cause subtle alterations in behavior of fish: effect of particles size and concentration?
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Studiebegeleiding
Om je te helpen je studie succesvol en vlot te doorlopen biedt de Universiteit Leiden intensieve begeleiding en advies aan. Toch kan het gebeuren dat het studeren niet zo optimaal verloopt als je had gehoopt. Weet dan dat je altijd bij ons terecht kunt voor ondersteuning op maat.
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Corruption & Integrity in the Netherlands (1945 - present)
Corruption, integrity (or a lack thereof…) and public values are near omnipresent elements in public administration and politics of all times. Cases of corrupt public officials and politicians continuously emerge. Strangely enough, however, it often remains unknown what actually occurred, how something…
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Tuning in to star-planet interactions at radio wavelengths
Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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Statistical modelling of time-varying covariates for survival data
This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Structural and functional analysis of proteins involved in natural product biosynthesis and morphological differentiation in Streptomyces
Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.
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High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier
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Small scale kinematics of massive star-forming cores
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde
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Lipid mediated colloidal interactions
The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.
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EuDEco
EuDEco (modellering van de Europese Data Economie) is een Coordination & Support Action (CSA) die financiering ontvangt van het Europese Horizon 2020 programma.
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Jimpitan in Wonosobo, Central Java: an indigenous institution in the context of sustainable socio-economic development in Indonesia
In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.
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Nuclear magnetic resonance force microscopy at millikelvin temperatures
Promotor: T.H. Oosterkamp
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
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Multivariate Humanities
Dit op casestudies gebaseerde Engelstalige boek over multivariate analyse voor gevorderde studenten in de geesteswetenschappen legt de nadruk op beschrijvende, exploratieve analyses van verschillende soorten datasets uit een breed scala van subdisciplines, waarbij het gebruik van multivariate analyse…
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Materials Innovative Technologies Assessment (MIN-TEA)
How can prospective LCA be streamlined in a way that its practical application in research and technology development increases?
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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CarbonCap
In the CarbonCap project, consumption oriented technological options and policy measures are identified as an addition to the present EU and world climate policy.
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Interactive scalable condensation of reverse engineered UML class diagrams for software comprehension
Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)
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A monograph of the plant genus Trigonostemon Blume
Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.
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On electronic signatures of topological superconductivity
Promotor: Prof.dr. C.W.J. Beenakker
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The environmentally-regulated interplay between local three- dimensional chromatin architecture and gene expression
Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.
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Do fungi differ? Understanding the mechanisms of mycorrhizal fungal impacts on soil C sequestration
How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?
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Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
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RAISE Onderzoek
Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…
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The hunt for frozen organic molecules in space
Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Toelatingseisen
Check de volgende toelatingseisen voordat jij je aanmeldt voor de opleiding Biologie.
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Developmental effects of polystyrene nanoparticles in the chicken embryo
There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.
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Research-based education (Engelstalig)
Didactiek
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‘Van Plato tot Pussy Riot’, wat is muziek?
Is het de taak van de muziek om ons te vermaken, te raken of te verheffen? De Academie der Kunsten start een nieuw keuzevak dat het fenomeen muziek onderzoekt vanuit filosofisch en historisch perspectief. Het vak gaat in september van start en iedereen kan het volgen.
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Componeren met microfoons en luidsprekers
Componist Cathy van Eck onderzoekt de unieke kenmerken van microfoons en luidsprekers in de creatie van muziek. Voor haar promotieonderzoek schrijft Van Eck 28 composities en een tekst. Concert 16 december, lezing en promotie 17 december.
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Meeloopdag - Research Master: Clinical & Health Psychology
Studievoorlichting
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Meeloopdag - Research Master: Clinical & Health Psychology
Studievoorlichting
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LCN2 Seminar: Network model selection via the Minimum Description Length principle: the effects of ensemble non-equivalence
Lezing
- PhD candidate in Developmental Psychology
- How to research medieval books? (5 ECTS)
- How to research medieval books? (5 ECTS)
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Assistant/Associate professor in Quantitative Ecology (0.8-1.0 fte)
Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)
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Weduwe schenkt Casimirfonds voor interdisciplinaire natuurkunde
De Casimir Research School viert deze zomer zijn eerste lustrum. Ter gelegenheid hiervan en om te gedenken dat Hendrik Casimir deze zomer 100 zou zijn geworden, schenkt zijn weduwe Josina Casimir-Jonker de Research School een fonds om activiteiten voor masterstudenten te bekostigen.
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Meeloopdag - Research Master: Social & Organisational Psychology (geannuleerd)
Studievoorlichting