The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Op 10 oktober 2019 verdedigde Janneke Vink haar proefschrift 'The Open Society and Its Animals'. Het promotieonderzoek is begeleid door promotor prof.dr. P.B. Cliteur.

Op 29 april 2020 verdedigde Beth Van Schaack haar proefschrift 'Imagining Justice for Syria: Water Always Finds Its Way'. Het promotieonderzoek is begeleid door promotor prof.dr. C. Stahn.

Op 1 november promoveert Andrew Wigman. Het Leiden University Centre for Linguistics feliciteert Andrew!

Schuurman onderzoekt hoe Rusland zijn geheime operaties tegen Europese landen laat escaleren.

It’s Not Easy Being Green – maar we zijn hier om te helpen! Wil je duurzamer leven maar heb je geen idee waar je moet beginnen? Ben je geïnteresseerd in het groener maken van de wereld en wil je hot topics doorgronden? Of sta je sceptisch tegenover klimaatverandering en wil je meer weten over de…

Het Leiden Instituut voor Geschiedenis heeft een uitzonderlijk sterke expertise in premoderne Europese geschiedenis in haar mondiale context, met specialisten wier interesses vrijwel het hele continent bestrijken. We hebben een sterke staat van dienst in het leiden van grotere onderzoeksteams en werken…

Promotie

Promotie

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

This article 'Shaping the European External Action Service and its post-Lisbon crisis management structures: an assessment of the EU High Representatives’ political leadership' assesses the role, influence and core aspects of the EU High Representatives’ (HR/VPs) “political leadership” in the context…

Promotores: Prof.dr. S.J. Edixhoven, Prof.dr. E. Ullmo (University Paris-Sud)

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Op 10 maart 2021 verdedigde Pieter Huizing zijn proefschrift 'Parallel Enforcement of International Cartels and Its Impact on the Proportionality of Overall Punishment'. Het promotieonderzoek is begeleid door promotor prof.mr. T.R. Ottervanger.

In this article, Eamon Aloyo argues that university supervisors should not use student evaluations of teachers as a measure of teaching effectiveness.

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Promotor: A. Kros

Hoewel veel beroepsbeoefenaren in de gezondheidszorg aangeven vaak gebruik te maken van placebo-effecten en de mechanismen ervan, is er weinig formele training over hoe om te gaan met placebo- en nocebo-effecten in de klinische praktijk. Dit project wil deze kloof tussen wetenschappelijke kennis over…

Op 23 juni 2020 verdedigde Santy Kouwagam haar proefschrift 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. C.E. von Benda-Beckmann.

Op 23 oktober 2019 verdedigde Yoram Stein zijn proefschrift 'Spinoza's Theory of Religion: The Importance of Religion in Spinoza's Thought and Its Implications for State and Society'. Het promotieonderzoek is begeleid door promotor prof.dr. P.B. Cliteur en prof.dr. A.A.M. Kinneging.

Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov

Op 26 juni 2019 verdedigde Lisa Louwerse haar proefschrift 'The EU’s Conceptualisation of the Rule of Law in its External Relations: Case Studies on Development Cooperation and Enlargement'. Het promotieonderzoek is begeleid door promotor prof. mr. C.A.P. Hillion.

What determines civic engagement in transboundary hydropolitics and why has it been muted in the Eastern Nile Basin?

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Bij de afwikkeling van faillissementen is de rol van de curator soms te groot. Dat betoogt prof.mr. Reinout Vriesendorp tijdens zijn oratie op 24 juni.

Hoe kunnen de problemen worden verklaard bij het opzetten van een duurzaam gemeenschappelijk veiligheids- en defensiemechanisme voor de EU?

Kun je algoritmes toepassen in de zorg? Marco Spruit, onderzoeker bij LIACS en LUMC, werkt hieraan binnen het Population Health programma van de Universiteit Leiden. Aan AG Connect vertelde hij hoe hij dat doet.

Een diversere groep studenten kun je je bijna niet voorstellen. India, Duitsland, Pakistan, Nederland, Israël, Rusland, Italië en Mongolië, allemaal voorbeelden van landen die dit voorjaar vertegenwoordigd zijn in de pilot van het International Leiden Leadership Programme.

Op donderdag 7 en vrijdag 8 december 2017 organiseerden het Hazelhoff Centre for Financial Law van de Leidse rechtenfaculteit en het European University Institute in Florence een PhD workshop in Leiden.

Project LAWKI (Life As We Know It) van ACPA promovenda Roosje Klap (ARK) heeft een Gouden Kalf Award 2022 gewonnen in de categorie Beste Digitale Cultuurproductie.

This course explores international arbitration as one of the most common methods of international dispute settlement. You will gain an in-depth understanding of international arbitration through the analysis of its role as a mechanism of dispute settlement, its institutions, the fields of law it is…

Promotor: Prof.dr. H.L.V. Linnartz

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

This course uses the lives, ideals and achievements of Theodore, Franklin, and Eleanor Roosevelt to create the idea of a Rooseveltian century. It is an invitation to think critically and historically, and it wants to give you a glimpse of what it means to be a historian at work.

When a star is born in our Galaxy, it is quite likely that it has formed within a massive cluster, which hosts numerous high-mass stars bathing their lower mass neighbours in UV radiation.

In the Schouwburgstraat, LUGO is currently redesigning the back-garden in order to increase biodiversity and make it a more beautiful space. Throughout October 2023 until March 2024, we will be making changes to the garden with our team of volunteers.

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

Promotor: P.D. Grünwald

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

With tomography it is possible to reconstruct the interior of an object without destroying.

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.