400 zoekresultaten voor “able and exploitation” in de Publieke website
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes
Almost all bacteria are enveloped by a cell wall that provides cellular protection.
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Far from home: the science exploitation of the fastest Milky Way stars
The Sun and all the stars in the night sky reside in the Milky Way galaxy. In the at-rest reference frame of the Galaxy, typical stars travel with velocities of about 100-200 kilometres per second.
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Invariant manifolds and applications for functional differential equations of mixed type
Promotor: S.M. Verduyn Lunel
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Transborder Governance of Forests, Rivers and Seas
Natural resources often stretch across borders that separate modern nation states. This can create conflict and limit opportunities for regulated consumption of their goods and services, but also provide opportunities for joint multinational efforts that exceed single country capabilities.
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PhD Thesis Pieter Boonstra
Pieter Boonstra (RUG) will defend his PhD thesis (Reading by example. The communication of religious knowledge in the collationes of the Brothers of the Common Life) on Thursday, 2 September 2021, at 14:30. Pieter was part of the NWO-funded research project 'Communication and Exploitation of Knowledge'…
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Musems, Collections and Society | Yearbook 2020
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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Musems, Collections and Society | Yearbook 2021
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Citizenship, Migration and Global Transformations
Europese burgers worden geconfronteerd met uitdagingen op het gebied van globalisering, migratie, technologische ontwikkelingen en klimaatverandering. Deze uitdagingen vergen het uiterste van onderlinge internationale en intergenerationele solidariteit, wat rechtstreeks betrekking heeft op de grondslagen…
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Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
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A composite indicator for evaluating safety and sustainability by design and circularity in emerging technologies
De eerste index om de veiligheid, duurzaamheid en circulariteit van producten te meten, waarmee ze het EU-kader (SSbD) operationaliseren.
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Ice and Gas in Protostellar Clouds and Planet-forming Disks
This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.
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Where photons meet phonons
We investigate how radiation pressure can be used to influence the mechanical motion of a micro-mirror suspended from springs.
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Measuring wellbeing in climate and socioeconomic scenarios
Over the past two centuries, socioeconomic development has improved material living standards but has also intensified environmental pressures, including climate change and biodiversity loss.
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Synthesis and Characterization of Boron, Nitrogen, and Carbon-Based Two-Dimensional Materials
This thesis comprises the development of reproducible synthesis procedures for two-dimensional materials (composed of boron, nitrogen and carbon) on different metallic surfaces.
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Orion's Dragon and Other Stories
Stellar feedback is a crucial ingredient in the evolution of galaxies.
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From every angle: novel insights into CC chemokine receptor 2 pharmacology
The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.
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Aria of the Dutch North Sea
Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn
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Women Writing Mexico (WWM)
Women Writing Mexico (WWM) is a network of women and men concerned with the human rights crisis in Mexico and more specifically, with the impact of structural forms of poverty, everyday violence, and discrimination based on gender, race, social class, and ethnicity, that particularly have an impact…
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From molecules to monitoring: Integrating genetic tools into freshwater quality assessments
Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.
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Molecular characterization of copper-dependent enzymes involved in Streptomyces morphology
Promotor: G.P. van Wezel, Co-promotor: D. Claessen
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A systematic literature review of security and privacy by design principles, norms, and strategies for digital technologies
Dit artikel biedt een systematisch literatuuronderzoek van de belangrijkste principes, normen en strategieën van Security by Design en Privacy by Design.
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Night Spaces: Migration, Culture and Integration in Europe (NITE)
Hoe worden nachtruimtes verbeeld, geproduceerd, ervaren en verteld door migrantengemeenschappen in Europa? Dit onderzoeksproject onderzoekt deze vraag in acht Europese steden: Aarhus, Amsterdam, Berlijn, Cork, Galway, Lissabon, Londen en Rotterdam.
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Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
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Chinese assertiveness and the rise of Xi Jinping: ideational mobilization, elite contestation, and the struggle over regional order
In 2009-2010 ontstond in het westerse discours het idee van een meer ‘assertief’ China, een opvatting die China krachtig van de hand wijst. Niettemin is, vooral sinds Xi Jinping in 2012 aan de macht kwam, duidelijk dat China zijn lang gehanteerde buitenlandse beleidsdoctrine van ‘een lage profilering…
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Formulation of influenza T cell peptides: In search of a universal influenza vaccine
Promotores: Prof.dr. G.F.A. Kersten, W. Jiskoot, Co-promotor: J-P. Amorij
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Protostellar jets and planet-forming disks: Witnessing the formation of Solar System analogues with interferometry
The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.
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Recognition, immune evasion, and exploitation of DNA viruses
Promotie
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Surveying young stars with Gaia: Orion and the Solar neighbourhood
OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.
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Can traditional forest management protect and conserve ironwood (ulin) stands? An option and approach in East Kalimantan
Promotores: G.A. Persoon, H.H. de Iongh
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not a man’s problem? Comparing post #MeToo policy and awareness training in the Dutch and French cultural sectors
Why do sexual violence policies still fail to systematically address men and masculinities, when the need for cultural change among men has been central in public debates since #MeToo?
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Spectral localisers and aperiodic topological phases in noncommutative geometry
The dissertation offers new tools and insights to computation and modelling of topological phases, with an emphasis on the aperiodic setting.
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Towards circular and energy-efficient management of building stock
Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.
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Mensenhandel
Onderzoeksproject naar mensenhandel binnen het instituut voor Strafrecht en Criminologie, Faculteit der Rechtsgeleerdheid, bij de Universiteit Leiden.
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Communicating in Legal English
Ontdek de cursus Communicating in Legal English van de Leiden Law Academy en verbeter uw juridisch Engelse vaardigheden. Lees hier meer!
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The versatility of asymmetric aminoethyl-tetrazines in bioorthogonal chemistry
This thesis describes the synthesis, analysis of various tetrazine bearing compounds and use in bioorthogonal chemistry.
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some thoughts on self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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Peptide amphiphiles and their use in supramolecular chemistry
Promotor: Prof.dr.ir. J.G.E.M. Fraaije, Co-promotor: A. Kros
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Phase separation in lipid-based nanoparticles: exploring the nano-bio interface
This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.
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Dancing with the Stars
This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.
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From stress to success; How actinobacteria exploit live without a cell wall
The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.
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Computational modeling of mycobacterium infection and innate immune reponse in zebrafish
Promotor: Prof.dr. J.N. Kok
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Electroextraction approaches for preconcentration of metabolites
In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.
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Chasing cosmic tau neutrinos in the abyss
In this work the reconstruction of a tau neutrino signal in the KM3NeT detector is discussed.
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Innovative sample preparation and handling strategies for automated and high-throughput metabolomics
Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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Transglycosylation of N-acylethanolamines
N-acylethanolamines (NAEs), including N-arachidonoylethanolamine (anandamide, AEA), N-palmitoylethanolamine (PEA) and N-oleoylethanolamine (OEA), are signaling lipids that play an important role in different physiological process.