Biopolymer sequencing with graphene edge-based tunnel junctions has the potential to overcome current limitations with the third generation of sequencing based on biological nanopores.

Op 17 november 2020 verdedigde Shuai Guo zijn proefschrift 'Recognition of Foreign Bank Resolution Actions'. Het promotieonderzoek is begeleid door promotoren prof.dr. R.D. Vriesendorp en prof.dr. M. Haentjens.

Promotor: M.T.M. Koper, Co-promotor: L. Juurlink

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

Individuen die werken in de publieke sector zien zichzelf geconfronteerd worden met tegenstrijdige waarden, tegenstrijdige eisen en de noodzaak van het dienen van het soms moeilijk definieerbare publieke belang.

The Role and Effectiveness of the G20. In dit artikel, gepubliceerd in The Changing Global Order onderdeel van the United Nations University Series on Regionalism book series, bespreekt auteur Jaroslaw Kantorowicz de evolutie van de G20.

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Ramesh Ganohariti onderzoekt de juridische identiteit in drie post-Sovjet aspirant-lidstaten en schetst in dit artikel vier veelvoorkomende scenario's.

Op 9 april promoveert Manolis Fragkiadakis. Het Leiden University Centre for Linguistics feliciteert Manolis!

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

Alessandro Tonutti heeft op 5 september 2017 zijn proefschrift:

EUMOTIONS onderzoekt welke rol emoties van politieke elites (op EU- en lidstaatniveau) spelen in het formuleren van beleidsmogelijkheden van de EU tijdens internationale crises.

The thesis is about how auxin and AGC kinases regulate male fertility. The main AGC kinases studied in this thesis is PDK1, PDK2 and AGC1.5, AGC1.7.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.

In dit artikel wordt betoogd dat de weerstand tegen groene overheidsinvesteringen afhankelijk is van de wijze van financiering.

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

8 november jl. heeft Marike Knoef een award gewonnen op de 34ste Award Ceremony van de World Cultural Council (WCC).

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

Het doel van dit proefschrift was om mogelijke risicofactoren voor overgewicht in de vroege kindertijd te ontdekken die als basis kunnen worden gebruikt voor het ontwikkelen van opvoedinterventies voor het verminderen van overgewicht.

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Academici hebben op het gebied van inlichtingen geworsteld met de vraag onder welke voorwaarden internationale samenwerking op het gebied van inlichtingen plaatsvindt. De meeste richten zich op transactionele motieven en gegarandeerde opbrengsten, de zogenaamde ‘Quid pro Quo’. Tegelijkertijd wordt vertrouwen…

Media spelen een belangrijke rol in het functioneren van het Nederlandse parlement. Kamerleden zijn veelal nieuwsjunkies en de berichtgeving die zij consumeren speelt daardoor een rol in hun dagelijks werk. Zo hebben diverse onderzoekers aangetoond dat media-aandacht een sterke invloed heeft op zogenaamde…

Dit proefschrift richt zich op de opvattingen en percepties van Chinese en Nederlandse docenten over de rol van onderzoek in het hoger onderwijs.

Wat beïnvloedt het gedrag van verantwoordingsforums?

In dit artikel onderzoekt Amandine Lerusse hoe de volgorde van prestatie-informatie de prioriteringsbeslissingen van lokale politici beïnvloedt.

This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…

Bernard Bernards onderzoekt beperkingen op innovatie door te focussen op cognitieve onzekerheid als toestand die innovatief werkgedrag kan beïnvloeden.

Promotor: Prof.dr. P. Hooykaas, Co-promotor: R. Offringa

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Op 17 oktober verdedigde Annelies van Vark het proefschrift 'Separation and immersion: the changing role of the armed forces in Northwestern liberal democracies'. Het promotieonderzoek is begeleid door Maartje van der Woude en Erwin Muller.

Software development is a complex process. It is important that software products become stable and maintainable assets.

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.