593 zoekresultaten voor “fire use” in de Publieke website
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Accountable Artificial Intelligence: Holding Algorithms to Account
Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…
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Linkages of Sustainability
Exploring linkages between energy and material use and implications for sustainable development.
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Thrips resistance in Gladiolus: an eco-metabolomic approach
Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.
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Stock-driven Scenarios on Global Material Demand
The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…
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Wild versus domestic prey in the diet of tigers
A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.
- Foundations of Research – 2: Conceptualization, Research Questions, Composition (3 ECTS)
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Empirical Bayes applications in biomedical high-dimensional prediction
The thesis introduces three methods for high-dimensional prediction problems in the biomedical field. The methods make use of empirical and variational Bayes in the estimation.
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Policy Review on Decoupling
Development of indicators to assess decoupling of economic development and environmental pressure in the EU-25 and AC-3 countries.
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LC-Impact
How can we develop and further improve life cycle impact assessment methods, characterisation factors and normalisation factors?
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Fostering Curiosity Through Video Games
This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.
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Improvisations in phototrophy
Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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Fertility and fontanels: women’s knowledge of medicinal plants for reproductive health and childcare in western Africa
Promotor: E.F. Smets, Co-promotor: T.R. van Andel
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Stefano Merciai
Wiskunde en Natuurwetenschappen
s.merciai@cml.leidenuniv.nl | +31 71 527 2727
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EPCEM 2001: Differences in the authorization process of GMOs in the EU and the USA
This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…
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Bioorthogonal Antigens
The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.
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Josephson and noise scanning tunneling microscopy on conventional, unconventional and disordered superconductors
In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…
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Personalised medicine for multiple outcomes: methods and application
The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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Activity-based proteomics of the endocannabinoid system
This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.
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Going global to local: achieving agri-food sustainability from a spatially explicit input-output analysis perspective
The global agri-food system plays a critical role in food security and environmental issues.
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The chlorine chain study
A substance flow analysis, covering about 99 % of the flows of chlorinated substances in the Netherlands.
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Data Centres for Natural Recources and Products
Creating information portals for support of European environmental policy.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Ecology of the Ethiopian wolf (Canis simensis Rüppell 1835) in a changing landscape: Human carnivore interactions in Afroalpine ecosystems of
Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.
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LCA of Printed and E-paper Documents
Comparing the global warming potential (GWP) of the service provided by an iRex Digital Reader to the same service provided by an office printer using a scanning LCA.
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An Online Corpus of UML design models: Construction and empirical studies
Promotores: J. Kok, M. Chaudron (Chalmers University)
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Chainet - European network on chain analysis for environmental decision support
Analytical tools for environmental design and management in a systems perspective. The combined use of analytical tools.
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Ubar Kampung
The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…
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Economic value of non-timber forest products among Paser Indigenous People of East Kalimantan
Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh
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Nonparametric Bayesian Methods in Robotic Vision
In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.
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CML-IA Characterisation Factors
CML-IA is a database that contains characterisation factors for life cycle impact assessment (LCIA) and is easily read by the CMLCA software program.
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Pesticides Atlas, Pilot Study
Description of Atlas of the surfacewater concentrations of pesticides in the Netherlands, a pilotstudy.
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Solution for Critical Raw Materials - an European Export Network (SCRREEN)
Where and how are critical materials currently used and how can this information be used to develop scenarios about their future demand.
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China’s industrial carbon emissions: Historical drivers at the regional and sectoral levels and projections in light of policy
This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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Using cryo-EM methods to uncover structure and function of bacteriophages
Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.
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Expanding the coverage of ecosystem services in life cycle assessment: an interdisciplinary venture
To contribute to the body of knowledge aiming at a better coverage of ecosystem service assessment in LCA studies, this thesis dives into the challenges of incorporating existing ecosystem service methods within the impact assessment phase of the conventional LCA framework.
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Impact of nitrogen fertilization on the soil microbiome and greenhouse gas emission
The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.
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Freedom of additional signals on genes: on the combination of DNA mechanics, genetics and translation speed
DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.
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Taxonomy, systematics, and biogeography of Ficus subsection Urostigma (Moraceae)
Promotor: Prof.dr. P.C. van Welzen
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Novel approaches for direct exoplanet imaging: theory, simulations and experiments
The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink
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Squaramide-based supramolecular polymers : from self-assembly to in vivo application
The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.
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Glycosyl Cations in Glycosylation Reactions
This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.
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Magnetic imaging of spin waves and magnetic phase transitions with nitrogen-vacancy centers in diamond
The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…