1,008 zoekresultaten voor “immune system” in de Publieke website
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Simona Demkova over Enforcement Challenges in Multilevel Regulatory Systems
Op 15 en 16 december nam Simona Demková deel aan een afsluitende conferentie en boekpresentatie van het doctorale opleidingsprogramma van de Universiteit van Luxemburg over ‘Enforcement Challenges in Multilevel Regulatory Systems – DTU REMS.
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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NWO-subsidie voor optimaal ontwerp van Cyber Physical Systems
NWO heeft een subsidie toegekend voor nieuw onderzoek naar Complex en Distributed Cyber-Physical Systems (CPS). Todor Stefanov Associate Professor aan het Leiden Institute of Advanced Computer Science (LIACS), en Andy Pimentel, Associate Professor aan de Universiteit van Amsterdam ontvingen in totaal…
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Balanced lethal systems: een quick guide door Ben Wielstra
Ben Wielstra onderzoekt balanced lethal systems, waarin de helft van het nageslacht al voor de geboorte sterft. In vakblad Current Biology legt hij op toegankelijke wijze uit hoe zoiets nadeligs kan ontstaan in de natuur.
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On metrics and models for multiplex networks
In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.
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Improving juvenile justice systems in Europe: Training for professionals
Prof. Ton Liefaard en dr. Stephanie Rap (m.m.v. Apollonia Bolscher LL.M.) zijn betrokken bij het ontwikkelen van een training Toolkit en Manual voor het project Improving Juvenile Justice Systems in Europe: Training for Professionals (JUST/2013/FRC/AG).
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Immune checkpoint inhibitors in mesothelioma
Promotie
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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Integrating Analytics with Relational Databases
The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.
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Adaptive Streaming Applications: Analysis and Implementation Models
Promotor: Prof.dr. E. Deprettere
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An engineering approach to decode immune responses
Promotie
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Single-cell immune profiling of atherosclerosis
Promotie
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Identification of regulators of cancer - immune interactions
Promotie
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Dissecting the immune microenvironment of breast cancer
Promotie
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Workshop over Access to Justice and the EU’s Remedies System
Op 3 en 4 november 2022 organiseerde Melanie Fink een workshop voor de auteurs van de samengestelde uitgave ‘Access to Justice and the EU’s Remedies System’. Het boek zal naar verwachting begin 2024 verschijnen bij Cambridge University Press.
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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Semi-partitioned Scheduling and Task Migration in Dataflow Networks
Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov
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Immune Thrombocytopenia: Exploring antibodies, scintigraphy and immune modulation. Moving towards a new era for patients with ITP
Promotie
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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Metastability for low-temperature Kawasaki dynamics with two types of particles
Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi
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Suiting Ding
Wiskunde en Natuurwetenschappen
s.t.ding@cml.leidenuniv.nl | +31 71 527 5615
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Oliver Taherzadeh
Wiskunde en Natuurwetenschappen
o.a.taherzadeh@cml.leidenuniv.nl | +31 71 527 2727
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Hai Lin
Wiskunde en Natuurwetenschappen
h.x.lin@cml.leidenuniv.nl | +31 71 527 7460
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Bartolomeus Häussling Löwgren
Wiskunde en Natuurwetenschappen
b.j.p.m.haussling.lowgren@cml.leidenuniv.nl | +31 71 527 2727
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Individualized prognosis in childhood immune thrombocytopenia
Promotie
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Chemische verbinding beïnvloedt afweersysteem
Chemici, waaronder Sander van Kasteren en Hermen Overkleeft, hebben ontdekt dat azides, een bepaalde chemische verbinding, specifieke T-cellen kunnen laten reageren op een vaccin of juist het vaccin kunnen laten negeren. Publicatie in Angewandte Chemie.
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Ben Wielstra
Wiskunde en Natuurwetenschappen
b.m.wielstra@biology.leidenuniv.nl | +31 71 527 5135
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Jennifer Anderson
Wiskunde en Natuurwetenschappen
j.a.anderson@cml.leidenuniv.nl | +31 71 527 2727
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Fatemeh Mehrafrooz Mayvan
Wiskunde en Natuurwetenschappen
f.mehrafrooz.mayvan@liacs.leidenuniv.nl | +31 71 527 2727
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Ecological functioning of bacterial chitinases in soil
Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)
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Exploring the interactions of M dwarf winds and cosmic rays
This thesis focus on the interaction between M dwarf stellar winds and Galactic cosmic rays and the possible effects on the habitability of exoplanets.
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Bioorthogonal Labeling Tools to Study Pathogenic Intracellular Bacteria
In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.
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Ginsenosides as selective glucocorticoid drugs: agonists, antagonists, and prodrugs
Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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Probing quantum materials with novel scanning tunneling microscopy techniques
This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Single cell mechanics for disease biology and pharmacology
In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.
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Tracing the journey of the sun and the solar siblings through the Milky Way
Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown
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Md Faysal Tareq
Wiskunde en Natuurwetenschappen
m.f.tareq@cml.leidenuniv.nl | +31 71 527 2727
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Exploring future multi-messenger Galactic astronomy
For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.