1,432 zoekresultaten voor “modelling simulations” in de Publieke website
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De relativiteit van wettelijke normen
Geen verplichting tot schadevergoeding bestaat, wanneer de geschonden norm niet strekt tot bescherming tegen de schade zoals de benadeelde die heeft geleden (artikel 6:163 BW). Maar hoe zou de rechter de relativiteit van een wettelijke norm moeten vaststellen?
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Me, My Fiends, and I
A neuro-ecological perspective on adolescent prosocial development
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Probing Gravity at Cosmic Scales
The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.
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Current challenges in statistical DNA evidence evaluation
Promotor: R.D. Gill, F. Taroni
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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CarbonCap
In the CarbonCap project, consumption oriented technological options and policy measures are identified as an addition to the present EU and world climate policy.
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How Electrostatic Interactions Drive Nucleosome Binding of RNF168 & PSIP1
The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.
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Higgs dynamics in the early universe
In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.
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Deciphering fermionic matter: from holography to field theory
Promotor: K.E. Schalm, Co-promotor: S.S. Lee
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Sizing up protoplanetary disks
This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.
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Making the invisible visible: paramagnetic NMR and the transient protein complex
Promotor: Prof.dr. M. Ubbink
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Aspects of cosmic acceleration
The focus of the dissertation
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The structure of the dusty cores of active galactic nuclei
Promotor: W. Jaffe, Co-promotor: K. Meisenheimer
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Ingredients of the planet-formation puzzle
High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.
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Lasers, lenses and light curves: adaptive optics microscopy and peculiar transiting exoplanets
Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen
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Disorder and interactions in high-temperature superconductors
This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.
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The role of zebrafish larvae for studying anxiety-like behaviour
The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.
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Gibbs Processes and Applications
Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.
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Modulation of plant chemistry by rhizosphere bacteria
Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.
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From midplane to planets : the chemical fingerprint of a disk
This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.
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Some case studies of random walks in dynamic random environments
Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Spin dynamics in general relativity
Promotor: J.W. van Holten
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The puzzle of protoplanetary disk masses
My work focuses on a class of astronomical objects called protoplanetary disks.
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Topological phases and phase transitions in magnets and ice
The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Breaking & Entering: PAH photodissociation and top-down chemistry
Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.
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Generalized Strictly Periodic Scheduling Analysis, Resource Optimization, and Implementation of Adaptive Streaming Applications
This thesis focuses on addressing four research problems in designing embedded streaming systems.
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BIM-regisseur/coördinator vastgoed
Vastgoed
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Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.
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Cochlear Implants: Bridging the gap between computational model and clinic
Promotie
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Aged human osteochondral explants as biomimetic osteoarthritis model
Promotie
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Improving immunotherapy for melanoma: models, biomarkers and regulatory T cells
Promotie
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Improving survival prediction models for liver transplantation candidates
Promotie
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A culture medium based approach to optimize the stratum corneum barrier of human skin equivalents
uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.
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Leergemeenschappen in conservatoriumonderwijs
Het beroep van musicus vereist sterke reflectieve, samenwerkende, creatieve en improvisatievaardigheden, maar de overheersende één-op-één-lessen in het conservatoriumonderwijs zijn vooral gericht op de overdracht van ambachtelijke vaardigheden. Door de effecten van het samenwerkend en ervaringsleren…
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Industrial Ecology
Het onderzoeksprogramma Industrial Ecology heeft als doel de ecologische transformatie naar duurzaamheid te ondersteunen van maatschappij en milieu. Het onderzoeksonderwerp is Industriële Ecologie in zijn breedste definitie, waaronder de analyse van milieusystemen en de integratie van de sociale en…
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Biomimetic redox reactions of the Cu(II) μ-thiolate complex
Promotor: Prof.dr. E. Bouwman
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Gravitatie, snaren, en materie met sterke wisselwerkingen
Wat is het verband tussen materie met zwakke en sterke gravitationele wisselwerkingen?
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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Statistics & Data Science (MSc)
De masteropleiding Statistics & Data Science is een tweejarige master waarbij een diep doorgronde introductie wordt gelegd aan de algemene filosofie en methodologie van statistische modellen, statistisch modelleren, data analyse en data science, met de voornaamste focus op toepassingen in levens- en…
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Data Science and Artificial Intelligence (BSc)
Bij Data Science & Artificial Intelligence leer je hoe je functies van het brein, zoals denken, geheugen, leren en aandacht in modellen kunt gieten. Deze kennis kun je gebruiken om computers en systemen op vergelijkbare of betere manieren te laten functioneren.
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Medicijnafbraak bij kinderen: wat gebeurt er in de nieren?
Welke dosis geneesmiddel geef je een kind? Dat hang voor een groot deel van af van hoe snel hun nieren dit medicijn weer uit het bloed verwijderen. Om ethische redenen is het onmogelijk om dit bij jonge patiënten te meten. Promovenda Sinziana Cristea combineerde verschillende modelleermethodes en veel…
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Nuno De Mesquita César de Sá
Wiskunde en Natuurwetenschappen
n.q.de.mesquita.cesar.de.sa@cml.leidenuniv.nl | +31 71 527 2727
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Md Faysal Tareq
Wiskunde en Natuurwetenschappen
m.f.tareq@cml.leidenuniv.nl | +31 71 527 2727
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Anjali Pandit
Wiskunde en Natuurwetenschappen
a.pandit@chem.leidenuniv.nl | +31 71 527 4198
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Peter van Bodegom
Wiskunde en Natuurwetenschappen
p.m.van.bodegom@cml.leidenuniv.nl | +31 71 527 7486
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Huub de Groot
Wiskunde en Natuurwetenschappen
groot_h@chem.leidenuniv.nl | +31 71 527 4539