1,376 zoekresultaten voor “synthesis he biology” in de Publieke website
-
Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
-
A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
-
Electron Paramagnetic Resonance Approaches to Study Biologically Relevant Reactions: Examples from Amyloid Aggregation to Enzymes
This thesis explores how electron paramagnetic resonance (EPR) spectroscopy can be used to investigate key biochemical processes.
-
The Agta of the Northern Sierra Madre. Livelihood strategies and resilience among Philippine hunter-gatherers
Promotores: G. Persoon, R. Schefold
-
Restoration of ditch bank plant diversity : the interaction between spatiotemporal patterns and agri-environmental management
Promotor: G.R. de Snoo, Co-promotor: C.J.M. Muster
-
Life In Plastic, Not Always Fantastic: Nano- and microplastics and their impact on terrestrial plants and the food chain
Plastics have become an integral part of modern society due to their versatility and durability.
-
Assessment of monitoring tools and strategies safeguarding aquatic ecosystems within the European water framework directive
CML rapport 192
-
Transborder Governance of Forests, Rivers and Seas
Natural resources often stretch across borders that separate modern nation states. This can create conflict and limit opportunities for regulated consumption of their goods and services, but also provide opportunities for joint multinational efforts that exceed single country capabilities.
-
Education
The specialisation Science Communication and Society (SCS) concerns science communication in a broad sense. The program focuses on the link between science and society and covers knowledge and skills in the field of science communication.
-
Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
-
The environmentally-regulated interplay between local three- dimensional chromatin architecture and gene expression
Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.
-
Hermen Overkleeft ontvangt Friedrich Wilhelm Bessel Research Award
Op voordracht van prof.dr. Roderich Suessmuth van de Technische Universiteit van Berlijn ontving prof.dr. Herman Overkleeft de Friedrich Wilhelm Bessel Research Award. Van Overkleeft is in Leiden verbonden aan het Leiden Institute of Chemistry, LIC/Bio-organic Synthesis.
-
Yunfei WuWiskunde en Natuurwetenschappen
y.wu@lic.leidenuniv.nl | 071 5272727
-
LIACS alumnus receives ACM Multimedia Rising Star Award
Former PhD student of the Leiden Institute of Advanced Computer Science (LIACS) Bart Thomee has received this year’s Rising Star Award from the Multimedia group of ACM, the worldwide computer science association. Today, Thomee is a successful researcher at Yahoo Labs.
-
Duizenden beelden van bevroren bacteriën
Hoe detecteren bacteriën signalen uit hun omgeving en hoe passen ze zich daaraan aan? Die vraag intrigeert Ariane Briegel, hoogleraar Ultrastructuurbiologie. Met behulp van nieuwe technieken produceert ze driedimensionale beelden, die nieuwe informatie geven over het zintuiglijke systeem van bacteri…
-
Klein maar niet zo fijn?
In hoeverre hopen nanodeeltjes zich op in planten en dieren, en welke eigenschappen van de deeltjes spelen hierbij een rol? Willie Peijnenburg, hoogleraar Milieutoxicologie en biodiversiteit kreeg een Marie-Curie beurs toegekend om onderzoek te doen naar de milieueffecten van nanodeeltjes.
-
Structural and synthetic biology of the human complement system
Promotie
-
Hermen Overkleeft wint de 2015 Jeremy Knowles Award
Prof. Hermen Overkleeft is bekroond met de 2015 Jeremy Knowles Award van de Royal Society of Chemistry voor zijn innovatieve en inzichtelijke ontwikkeling van activity-based eiwit probes voor de beeldvorming en de identificatie van enzymen in gezondheid en ziekte. Van Overkleeft is in Leiden verbonden…
-
‘The ILLP has been helpful for every human relation I have’
What is leadership? Can it be taught, and if so, how? The International Leiden Leadership Programme (ILLP) helps students find their own style, say ILLP graduate Marko Simovski and his former coach Annah Neve in an interview: 'It’s about you, discovering you.'
-
Publicatie hoofdstuk door Timo Slootweg in "Great Christian Jurists in the Low Countries"
Timo Slootweg, associate professor at he department Philosophy of Law, published a chapter about Paul Scholten in
-
Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
-
In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
-
Microglial lipid metabolism: a delicate balance
Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.
-
Lespakket Antibiotica Gezocht!
Zelf met leerlingen aan de slag in een zoektocht naar antibiotica? Met het practicum Antibiotica Gezocht! gaan bovenbouw havo- en vwo-leerlingen tijdens de biologieles op zoek naar (nieuwe) antibioticum-producerende bacteriën.
-
Bestrijdingsmiddelen en waterkwaliteit
Boek over bestrijdingsmiddelen en waterkwaliteit
-
Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
-
Can traditional forest management protect and conserve ironwood (ulin) stands? An option and approach in East Kalimantan
Promotores: G.A. Persoon, H.H. de Iongh
-
Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.
-
The Interactions of Human Mobility and Farming Systems and Impacts on Biodiversity and Soil Quality in the Western Highlands of Cameroon
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh
-
Upconverting nanovesicles for the activation of ruthenium anti-cancer prodrugs with red light
Promotor: E. Bouwman, Co-promotor: S. Bonnet
-
Chemical tools to monitor and control proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
-
Impact of land use changes on the human-elephant conflict
Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh
-
Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
-
Deciphering the complex paramagnetic NMR spectra of small laccase
Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.
-
The impact of sustainable forest management on plant and bird diversity in East Kalimantan, Indonesia
Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters
-
Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
-
Thermostable Nanodiscs for the development of novel biopharmaceuticals
Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…
-
Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
-
Zipping into Fusion
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
-
Transcultural Health Care Utilisation in Serengeti of Tanzania: Towards Applied Ethnoscience in Public Health Management
The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.
-
Prediction of spatial-temporal brain drug distribution with a novel mathematical model
A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.
-
Fisheries in the Waza Logone Floodplain. An Analysis of the Status of the Fisheries Sector and Mitigation of Conflicts within the Sector in North
Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh
-
Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet
-
Biologie
Biologie in perspectief
-
Roeland van der Rijst
Evaluatie in actie: ontwikkeling en implementatie van een mobiele applicatie voor tussentijdse feedback en onderwijsevaluaties.
-
Lesmiddelen om leerlingen betrokken te houden
Leerlingen en studenten leren het beste als ze actief met lesstof aan de gang zijn. Hoogleraar Wilfried Admiraal onderzoekt de beste lesmiddelen en opdrachten om dit voor elkaar te krijgen.
-
Taakgestuurd leren
Werken vanuit boeiende en relevante taken
-
Vooronderzoek naar de koloniale en slavernijgeschiedenis van de stad Leiden en de Universiteit Leiden
Hoe positioneerde onze academische gemeenschap zich ten opzichte van een systeem dat mensen van hun vrijheid beroofde? Welke rol heeft de universiteit als onderwijsinstelling ingenomen ten opzichte van kolonialisme en het slavernijsysteem? Hoe kunnen wij het beste omgaan met onze bijzondere collecti…
-
Helder beeld van bacteriën
Een bacterie supersnel bevriezen, om de structuur van buiten en binnen natuurgetrouw in beeld te brengen. Hoogleraar Ultrastructuurbiologie Ariane Briegel kwam speciaal hiervoor naar Leiden: de Universiteit Leiden is een van de weinige instituten wereldwijd waar de benodigde apparatuur beschikbaar is.…
-
Niko Tinbergenlezing 2019: Stamcellen, mini-organen en het eeuwige leven
Drie sprekers, drie boeiende wetenschapsverhalen en een goed gevulde zaal. De Niko Tinbergenlezing kende op 10 december 2019 een succesvolle hernieuwde start.