Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.

Hoe beïnvloedt de vernietiging van universiteiten in Gaza, ook wel 'scholasticide' genoemd, het wetenschappelijk leven en wat zijn de theoretische en juridische onderbouwingen van de term?

2025 markeert de 50e verjaardag van de eerste Wereldvrouwenconferentie van de Verenigde Naties (Mexico-Stad, 1975), een proces dat leidde tot de oprichting van de Beijing Declaration and Platform for Action (1995). Het Global Transformations and Governance Challenges Programme organiseerde een rondetafelgesprek…

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.

This thesis describes the synthesis, analysis of various tetrazine bearing compounds and use in bioorthogonal chemistry.

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

Promotor: T. H. Oosterkamp

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

Promotores: P. Stevenhagen, A. Enge Co-Promotor: T.C. Streng

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.

The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.

This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

Scott Waitukaitus is namens LION genomineerd als Discoverer of the Year 2017. Breng snel je stem uit!

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

Op 5 september 2019 verdedigde Jennifer Doekhie haar proefschrift 'Dimensions of desistance: A qualitative longitudinal analysis of different dimensions of the desistance process among long-term prisoners in the Netherlands'. Het promotieonderzoek is begeleid door promotor prof.dr. P. Nieuwbeerta.

Are you planning to conduct clinical research in the Netherlands? In this online course, you are introduced to legislation and procedures on clinical research in the Netherlands. It will help you prepare and submit your research file efficiently. The first three themes ‘The Dutch Review System’ , ‘The…

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…

The radio sky harbours both galactic and extragalactic sources of arcminute- to degree-scale emission of various physical origins. To discover extragalactic diffuse emission in the Cosmic Web beyond galaxy clusters, one must image low–surface brightness structures amidst a sea of brighter compact fore-…

Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.

In this work, I explore the creation of new methods that optimize simulations of the gravitational N-body problem. Specifically, I take advantage of the recent popularity of Machine Learning methods to find tools that can suit this problem.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

Radio jets are important to the evoultion of galaxies. However, it is still not fully understood how a radio jet can be triggered.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.

Promotor: V. Vitelli, Co-promotor: J. Paulose

Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer