Promotor: K.E. Schalm, Co-promotor: S.S. Lee

The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

The focus of the dissertation

Organic amendments applied to agricultural fields can partially offset our carbon emissions to the atmosphere and improve the resilience of agriculture to the effects of climate change. Driving these benefits, however, are complex and poorly understood interactions between organic amendment properties,…

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.

Geen verplichting tot schadevergoeding bestaat, wanneer de geschonden norm niet strekt tot bescherming tegen de schade zoals de benadeelde die heeft geleden (artikel 6:163 BW). Maar hoe zou de rechter de relativiteit van een wettelijke norm moeten vaststellen?

A neuro-ecological perspective on adolescent prosocial development

Heart failure is a major health care problem with high mortality.

This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.

Promotor: W. Jaffe, Co-promotor: K. Meisenheimer

Onderzoek naar representatieve bureaucratie heeft vaak de positieve prestatie-effecten bevestigd van bureaucratieën die de demografische kenmerken van hun cliënten weerspiegelen. Er is echter weinig bekend over de onderliggende mechanismen op individueel niveau die tot deze resultaten leiden.

One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.

Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

Van ambitie tot actie: autonoom leren structureel verankeren in het Leidse onderwijs

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Promotor: Prof.dr. M. Ubbink

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

Promotor: A. Kros

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

In de onderzoekslijn Geneesmiddelenonderzoek werken we voornamelijk met knaagdieren. Knaagdieren, zoals muizen, worden veel gebruikt als proefdier. Deze kleine zoogdieren zijn makkelijk te houden en planten zich snel voort.

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

Promotor: R. Cramer

Promotor: Prof.dr. M. de Jong

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

Hoe helpen demonstratie-experimenten in de klas leerlingen om te leren chemisch redeneren?

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

My work focuses on a class of astronomical objects called protoplanetary disks.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

Dit proefschrift onderzoekt hoe golven zich gedragen in een imperfecte omgeving. Denk aan een golf op het wateroppervlak na een passerende boot: ook als de boot al lang weg is, blijft de golf nog een tijd zichtbaar. Maar wat gebeurt er als de golf realistische oneffenheden of verstoringen tegenkomt?

Promotie