2,335 zoekresultaten voor “3d modelling” in de Publieke website
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Microstructural and Metabolic Alterations in the Zebrafish Brain Induced by Toll-Like Receptor 2 Deficiency
Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.
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Lithium-ion batteries and the transition to electric vehicles
The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.
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In vitro investigation of the photoprotection mechanism of Light Harvesting Complex II
Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.
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Tales of Orion: the interplay of gas, dust, and stars in the interstellar medium
Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L. Kaper (UvA)
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Travelling waves on trees and square lattices
In this thesis we study bistable reaction-diffusion equations on lattice domains.
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Stock-driven Scenarios on Global Material Demand
The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…
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Parallel evolution in an invasive plant species: evolutionary changes in allocation to growth, defense, competitive ability and regrowth of invasive
Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling
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The galaxy–dark matter connection: a KiDS study
In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.
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Semigroups on Spaces of Measures
Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille
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Principles of Environmental Sciences
Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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Focal-plane wavefront sensors for direct exoplanet imaging: Theory, simulations and on-sky demonstrations
One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…
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Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
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Lost in Chemical Space, Found in Data
Developing new medicines is one of modern science's most significant hurdles, a process marked by high costs, long timelines, and frequent failures of promising candidates.
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Hunting for the fastest stars in the Milky Way
The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.
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Na je studie
De meeste studenten die een bachelor Economie & Samenleving hebben afgerond volgen daarna nog een aanvullende master. Omdat het interessant is je nog verder te verdiepen in je vakgebied of omdat het je kansen op de arbeidsmarkt vergroot.
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On a quest to discover where stellar-mass black holes merge: testing the AGN binary formation channel with spatial correlation analyses
The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.
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Onderwijs
Het CLEI verzorgt een aantal vakken op het gebied van ondernemerschap en innovatie in juridische dienstverlening.
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Exploring Reactive Interfaces: Nanoplastics, Catalysts, and 2D Materials
This thesis investigates reactive interfaces in surface science across three domains: heterogeneous catalysis, environmental nanoplastics, and two-dimensional materials.
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Carcinogenicity of insulin analogues
Promotor: Prof.dr. B. van de Water
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Evaluation of Different Design Space Description Methods for Analysing Combustion Engine Operation Limits
Promotor: Prof.dr. T.H.W. Bäck
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The distribution of stellar mass in galaxy clusters over cosmic time
Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: H.Hoekstra
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Social support at work and at home: Dual-buffering effects in the work-family conflict process
Dr. Helen Pluut heeft een artikel gepubliceerd in het gerenommeerde tijdschrift Organizational Behavior and Human Decision Processes (OBHDP). Dit in samenwerking met Remus Ilies (National University of Singapore), Petru Curşeu (Open Universiteit en Babeş-Bolyai University) en Yukun Liu (University of…
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More JAZ in the orchestration of jasmonate-mediated plant defense
Prof.dr. J. Memelink
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The colours of the extreme universe
This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.
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Reconstruction Methods for Combined HAADF-STEM and EDS Tomography
The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.
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Betwist bestuur in Rotterdam: een bestuurskundige heranalyse
De centrale onderzoeksvraag in deze studie was tweeledig: 1. In hoeverre zijn de drie bestuurskundige reconstructiemodellen bruikbaar bij een reconstructie van het publieke besluitvormingsproces inzake decentraal bestuur tussen 1947 en 2014? 2. In hoeverre heeft de reconstructie van dit publieke besluitvormingsproces…
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Effects of the early social environment on song and preference learning in zebra finches
Songbirds as vocal learners learn their songs and song preference from social tutors. Tutor choice for both song and preference learning are important to characterize for understanding individual learning performance and cultural transmission of song.
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Winds in the AGN environment: new perspectives from high-resolution X-ray spectroscopy
Promotor: J.S. Kaastra Co-promotor: E. Constantini
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The connection between mass and light in galaxy clusters
Promotor: Koen Kuijken Co-promotor: Henk Hoekstra
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Adaptive responses to environmental changes in Lake Victoria cichlids
Promotor: M.K. Richardson, Co-Promotor: F. Witte
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Hybrid Quantum-Classical Metaheuristics for Automated Machine Learning Applications
This thesis investigates how quantum, quantum-inspired, and hybrid quantum-classical computation can enhance key points of the automated machine learning (AutoML) pipeline under the constraints of noisy intermediate-scale quantum (NISQ) devices.
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Discovery of BUB1 kinase inhibitors for the treatment of cancer
The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.
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Strategies for the improvement of genome editing in Arabidopsis thaliana
Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.
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Visual Relation extraction Based on Deep Cross-media Transfer Network
Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.
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Tail Regeneration in the Tokay Gecko (Gekko gecko)
Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.
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Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotores: Prof.dr. G.A. van der Marel, M. van Heel
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Uyt saecke des doots
Al eeuwenlang wordt in Nederland bij overlijden belasting geheven over de verkregen erfenissen. De heffing van deze erfbelasting staat niet alleen ter discussie vanwege de vermeende dubbele heffing en het beklemmende aanknopingspunt, maar ook vanwege de mogelijkheden om via slimme juridische constructies…
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Freezing conditions in warm disks: snowlines and their effect on the chemical structure of planet-forming disks
This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.
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Atmospheres of hot alien Worlds
Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
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Unraveling modular architecture and domain engineering of carbohydrate-active enzymes: key insights for sustainable bio-based processes
This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…
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Error bounds for discrete tomography
Promotores: K.J. Batenburg, B. Koren
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Destroy, Create, Transform and Sublimate. Laboratory Dissociation Studies on Polycyclic Aromatic Hydrocarbons and Analogues
The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).
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Steady-State Analysis of Large Scale Systems
Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Self-Adjusting Surrogate-Assisted Optimization Techniques for Expensive Constrained Black Box ProblemsBagheri, S.
Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.