Onderwaardeert de universiteit onderwijs ten opzichte van onderzoek? Kun je in de wetenschap doorgroeien zonder academische prijzen? Welke wetenschapper inspireert jou? Heeft de universiteit genoeg aandacht voor zowel jouw wetenschappelijke prestaties als jouw persoonlijk welzijn?

Femke Nijboer, universitair docent bij Gezondheids-, medische en neuropsychologie heeft een van de twee Nederlandse fellowships 2015 van L’Oréal-UNESCO Women in Science ontvangen. Dat gebeurde op 24 november bij de KNAW in Amsterdam.

Hoe kunnen we schaatsers met behulp van data-analyses nóg sneller laten schaatsen? Dr. Arno Knobbe en collega’s van het Leiden Centre of Data Science en het Leiden Institute of Advanced Computer Science doen daar onderzoek naar.

In relationele databases kun je informatie en data opslaan zonder dat de relaties tussen die data verloren gaan. Het zijn daarom nuttige instrumenten voor informatici. De vakgebieden van database-wetenschappers en informatici sluiten echter niet goed op elkaar aan, wat leidt tot inefficiënt gebruik…

In theory, states can gain security by acquiring internal arms or external allies. Yet the empirical literature offers mixed findings: some studies find arms and allies to be substitutes, while others find them to be complements. Political scientists Matthew Digiuseppe (Leiden University) and Paul Poast…

Open Science Hub, een onderwijsproject gecoördineerd door de Universiteit Leiden, heeft de Portugese Medal of Scientific Merit 2021 gewonnen voor haar bijdragen aan communitybuilding door middel van wetenschappelijk onderwijs, onderzoek en innovatie.

Jongeren beïnvloeden elkaar om meer risico te nemen, al ligt dat genuanceerder dan we vaak denken. Dat ontdekte de Leidse ontwikkelingspsycholoog Jorien van Hoorn. Bovendien blijken leeftijdsgenoten elkaar ook positief te beïnvloeden. Dat is tot nu toe onderbelicht. Promotie op 12 januari.

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

Promotores: G.A. Persoon, H.H. de Iongh

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

This dissertation presents new cryptographic protocols, which can be divided into two families.

Op 11 november 2021 verdedigde Mariana Gkliati het proefschrift 'Systemic Accountability of the European Border and Coast Guard'. Het promotieonderzoek is begeleid door promotoren prof.dr. P. Rodrigues en prof.dr. L. Besselink (UvA).

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.

M. Danhof, Co-promotores: J. Freijer, A. Yassen

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

Op 16 december 2021 verdedigde Lisanne van Houten het proefschrift 'Flexing the Slot Regime'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof. L. Pierallini (Luiss University Of Rome).

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Promotor: Prof.dr. H.S. Overkleeft

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu

Als een nieuwe methode is ontwikkeld om een (neuro-)psychologische aandoening of hieraan gerelateerde gedragsfactoren te herkennen en te behandelen, kan deze nog niet direct in de klinische praktijk worden ingezet. Eerst moet de methode geëvalueerd worden, bij voorkeur in gerandomiseerde, gecontroleerde…

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…