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Eeuwenlang was Nederland betrokken bij slavenhandel en slavernij, een geschiedenis van uitbuiting en onverholen racisme. Dat verleden speelde zich niet alleen ver weg af, in Afrika en de Cariben, ook dichtbij zijn er sporen van terug te vinden. Zo ook in Leiden zoals deze gids in een vierluik laat z…

Het voorgestelde project evalueert hoe de kwetsbaarheid van migrantenmannen en -vrouwen werd geconstrueerd in politieke, publieke en mediadiscoursen, en hoe verschillen in de geconstrueerde kwetsbaarheid van invloed waren op de beslissing om te migreren, het migratieproces en het daaropvolgende vest…

Dit deelproject pleit voor een nauwkeurige en forensische reconstructie van de financiële stromen van en naar de Sovjetrepublieken in Centraal-Azië in de naoorlogse periode.

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Promotor: Prof.dr. G.P. van Wezel

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Promotor: S.M. Verduyn Lunel

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

The field of science communication is very broad. Below is a list of organisations where SCS students can fulfill internships or where alumni have found jobs.

Promotores: Prof.dr. S.J. Edixhoven, Prof.dr. E. Ullmo (University Paris-Sud)

An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

Stellar feedback is a crucial ingredient in the evolution of galaxies.

Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Promotor: T.H. Oosterkamp

Heart failure is a major health care problem with high mortality.

Promotor: Prof.dr. W.J.G.M. Peijnenburg

De Faculteit Governance and Global Affairs (FGGA) richt zicht op onderzoek naar maatschappelijke en governancevraagstukken zoals terrorisme, organisatie van het openbaar bestuur, klimaatverandering en economische crises. Hedendaagse onderwerpen worden zowel vanuit een bestuurskundig, politicologisch,…

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

AI Labs zijn samenwerkingen van de Universiteit Leiden met externe partner zoals bedrijven, overheidsinstellingen en andere universiteit op het gebied van kunstmatige intelligentie. De Faculteit voor Wis-en Natuurkunde is uniek gesitueerd op het grootste Bioscience Park van Nederlands, en ligt direct…

Promotor: T. Schmidt

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Promotor: W. Jiskoot, Co-promotor: A. Hawe

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

Promotor: E.F. Smets, Co-promotor: T.R. van Andel

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L. Kaper (UvA)