Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…

Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.

Promotor: Prof.dr. F. den Hollander, G.Maillard

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Promotor: K.J. Batenburg

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.

Promotor: D. Bouwmeester, Co-promotor: D. Kraft

Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Promotor: J. A. Bouwstra

Promotor: Prof.dr. M. de Jong

Promotor: J. Aarts

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Didactiek

‘Ik wist niet dat ik op jou nog trotser kon worden.’ Zo reageerde de vader van Kristian Rietveld op het nieuws dat zijn zoon benoemd is tot Docent van het Jaar 2017.

Promotie

Promotie

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…

In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.

Dissociative chemisorption is an important reaction step in many catalytic reactions.

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.

Healthcare robots and AI is een onderzoek naar juridische en reguleringsaspecten van robots en kunstmatige intelligentie in de zorg.

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

We use DNA strands to stabilize few-atom silver clusters, which show unique optical and chemical properties. This thesis involves the study of these constructs for various applications.

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

Dit project beoogt de ontwikkeling van geavanceerde data-analysemethoden voor monitoring en het vergroten van ons inzicht in de dynamiek van de biodiversiteit in natuurgebieden zoals de Oostvaardersplassen.

Bij LIACS erkennen we de groeiende behoefte aan geavanceerde technische ondersteuning bij onderzoeksprojecten en labonderwijs. Toenemende studentenaantallen, steeds geavanceerdere hardware en infrastructuur, nieuwe eisen rondom dataveiligheid en -beheer, en de complexiteit van de kerncursussen informatica…

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

Promotor: G. J. Kroes

Promotor: M.A.G.J. Orrit

Na het afronden van de bacheloropleiding volgen verreweg de meeste studenten de masteropleiding.

Promotor: Prof.dr. M. Ubbink