De Centrale Biobank Organisatie van het LUMC helpt bij het implementeren van regels en voorschriften met betrekking tot geïnformeerde toestemming, verzameling, opslag en distributie van biomaterialen en gegevens voor biobanking.

Projecten van de afdeling Environmental Biology

Effectieve ontwikkelingshulp: gebruik lokale kennis en structuren. Projecten in ontwikkelingslanden om een deugdelijk bestuur op te zetten, mislukken vaak omdat de hulporganisaties zich onvoldoende verdiepen in de lokale kennis en mores, stelt Moosa Elayah. Een Local Bank of Knowledge kan een oplossing…

Binnen het Leids Universitair Medisch Centrum (LUMC) wordt in verschillende onderzoeksprojecten gebruik gemaakt van pathogene micro-organismen van risicogroep 3. Voor het werken met deze ziekteverwekkers beschikt het LUMC over een onderzoekslaboratorium met hoge inperking om de experimenten voor mens…

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.

The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

The use of increasingly large and diverse datasets to guide urban climate action has implications for how, and by whom, local governments are held accountable.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

Het LUMC iPSC Hotel biedt de generatie van research grade humane geïnduceerde pluripotente stamcellen (iPSC's) uit verschillende weefselbronnen met behulp van de modernste herprogrammeringstechnieken.

Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…

This thesis mainly focuses on multimodal understanding and Visual Question Answering (VQA) via deep learning methods. For technical contributions, this thesis first focuses on improving multimodal fusion schemes via multi-stage vision-language interactions.

Promotor: Prof.dr. J.N. Kok

In the traditional theory of linear elasticity, superposition dictates that the response of a material does not depend on the sequence of the applied mechanical actuations.

Kunnen we van quantum-verrassingen quantum toepassingen maken? Kunnen we het leven onderzoeken en opbouwen vanuit de nano-schaal?

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.

Search and conversational systems have become central to how people access information and perform tasks.

Lezing

Promotie

Promotor: H.J.M. de Groot

Lezing

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

Patterned detectors are an existing technology that can be found in almost all color cameras.

Big Science, commonly defined as conventional science made big in three dimensions, namely organizations, machines, and politics, brings a plethora of different stakeholders together, often for a long period of time. This includes policymakers, scientists, (scientific) managers as well as local “host”…

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.

Promotores: H. Schiessel, G.T. Barkema

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

The project Multimedia Research and Documentation of African Oral Genres: Connecting Diasporas and Local Audiences (Director: D.Merolla) focuses on multimedia as technology that allows scholars to share documentation and scientific knowledge with the cultural owners of the collected oral genres.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Hydrogen fuel cells are expected to be pivotal in the energetic transition towards renewable energy sources such as solar and wind power. However, their industrial scalability is severely hindered by the high cost and degradation rate of platinum catalysts, one of their key components. Addressing this…

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L. Kaper (UvA)

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

Dr. Helen Pluut heeft een artikel gepubliceerd in het gerenommeerde tijdschrift Organizational Behavior and Human Decision Processes (OBHDP). Dit in samenwerking met Remus Ilies (National University of Singapore), Petru Curşeu (Open Universiteit en Babeş-Bolyai University) en Yukun Liu (University of…

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Wij richten ons op natuurlijke producten van onderzoek, de traditionele geneeskunde, etnobotanie en fytochemie.

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Promotor: Prof.dr. T. Schmidt

Women Writing Mexico (WWM) is a network of women and men concerned with the human rights crisis in Mexico and more specifically, with the impact of structural forms of poverty, everyday violence, and discrimination based on gender, race, social class, and ethnicity, that particularly have an impact…

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

Op 13 oktober 2021 verdedigde Ross Spence het proefschrift 'Collateral Transactions and Shadow Banking'. Het promotieonderzoek is begeleid door promotoren prof.mr. M. Haentjens en prof.dr. A.M. Pacces (UvA).

Promotores: Prof. dr. G.R. (Geert) de Snoo, Dr. E. (Ester) van der Voet