This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

The expanding population and economic activity are driving up global energy consumption. Simultaneously, there is an urgent need to transition from fossil fuels to renewable sources to mitigate the climate crisis, primarily caused by fossil fuel combustion.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

De redactie van Biophysical Journal heeft een publicatie van Daniela Kraft uitgeroepen tot Paper of the Year 2017. De prijs wordt uitgereikt ter erkenning van buitengewone bijdragen van jonge onderzoekers.

The Role and Effectiveness of the G20. In dit artikel, gepubliceerd in The Changing Global Order onderdeel van the United Nations University Series on Regionalism book series, bespreekt auteur Jaroslaw Kantorowicz de evolutie van de G20.

Op de eerste dag van jouw nieuwe baan heb je zweethanden, ben je nerveus en onzeker, maar een paar maanden later zijn die gevoelens al weer verdwenen. Je hebt jouw nieuw rol eigen gemaakt en je bent nu onderdeel van de organisatie. Het proces dat daar naar toe leidt heet

Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

In de categorie bestuursrecht is Paul Adriaanse, samen met acht andere kandidaten, genomineerd voor de landelijke verkiezing van de Magna Charta Lawyer of the year. Het publiek kiest wie de advocaat van het jaar gaat worden.

Op 19 december 2019 verdedigde Reza Eftekhar zijn proefschrift 'The Role of the Domestic Law of the Host State in Determining the ratione materiae Jurisdiction of Investment Treaty Tribunals: The Partial Revival of the Localisation Theory'. Het promotieonderzoek is begeleid door promotor prof.dr. E.…

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Promotor: Prof.dr. B.R. Katzy

Promotor: A.P. IJzerman

Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…

Promotores: Prof.dr. M. Franx, Prof.dr. M. Kriek (Univ. of California at Berkeley)

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

Lezing, Workshop

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

Biopolymer sequencing with graphene edge-based tunnel junctions has the potential to overcome current limitations with the third generation of sequencing based on biological nanopores.

Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.

Promotor: Prof.dr. J. Kuiper

This dissertation is part of a broader research project that revolves around unraveling the evolution of balanced lethal systems.

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Promotor: G. van Dijk

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

Promotor: Prof.dr.ir. E. Deprettere

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

Op 7 september verdedigde Francesc Claret Traid het proefschrift 'On the nature of the right to resist: a rights-based theory of the ius resistendi in liberal democracies'. Het promotieonderzoek is begeleid door Afshin Ellian en Gelijn Molier.

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Dr. Joris Larik, universitair docent vergelijkend, EU- en internationaal recht bij LUC The Hague, is coauteur van het rapport 'UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco'.

Promotie

Op 31 januari 2018 verdedigde Vestert Borger zijn proefschrift getiteld ‘The Transformation of the Euro: Law, Contract, Solidarity’. Het promotieonderzoek is begeleid door professor Stefaan Van den Bogaert (promotor) en dr. Jorrit Rijpma (co-promotor).

Op 12 februari promoveert Cid Swanenvleugel. Het Leiden University Centre for Linguistics feliciteert Cid!

Langetermijnontwikkelingen, zoals het verouderen van de bevolking, de toename in de gemiddelde levensverwachting en de gevolgen van de recente financiële crisis, hebben bijgedragen aan de discussie rondom de houdbaarheid van het pensioenstelsel.

The researchers examine the Council of the European Union's voting behaviour between 2010 and 2021 and the impact of different independent variables.

Lezing, Lezingenreeks Vergelijkende Indo-Europese Taalwetenschap (CIEL)

Promotor: Prof.dr. A. Achucarro

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Promotor: Prof.dr. E. Bouwman

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

Promotor: E.F. Smets Co-promotor: J. Geml