High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

Op 31 januari 2018 verdedigde Vestert Borger zijn proefschrift getiteld ‘The Transformation of the Euro: Law, Contract, Solidarity’. Het promotieonderzoek is begeleid door professor Stefaan Van den Bogaert (promotor) en dr. Jorrit Rijpma (co-promotor).

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

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Promotor: G. van Dijk

Op 12 februari promoveert Cid Swanenvleugel. Het Leiden University Centre for Linguistics feliciteert Cid!

Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

The researchers examine the Council of the European Union's voting behaviour between 2010 and 2021 and the impact of different independent variables.

Hoe zetten belangenorganisaties in Nederland strategisch procederen in om politieke, maatschappelijke of juridische veranderingen te realiseren, en hoe verhoudt deze strategie zich tot andere klassieke vormen van beleidsbeïnvloeding?

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh

Promotor: S.J. Edixhoven, L.D.J. Taelman

Op 28 oktober 2022 sprak Yao Yuan op een congres in Rome over 'Understanding national security concerns in light of FDI screening'. Het congres werd georganiseerd door de Università Telematica internazionale UNINETTUNO en Uppsala University.

Langetermijnontwikkelingen, zoals het verouderen van de bevolking, de toename in de gemiddelde levensverwachting en de gevolgen van de recente financiële crisis, hebben bijgedragen aan de discussie rondom de houdbaarheid van het pensioenstelsel.

Dissochaeta Blume (Melastomataceae, tribe Dissochaeteae) is well-known as a scrambling plant genus found in Southeast Asia, where it is an inhabitant of the tropical rainforests or evergreen forests.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.

Promotor: Prof.dr. W.T.F. den Hollander

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

Op 11 november 2021 verdedigde Mariana Gkliati het proefschrift 'Systemic Accountability of the European Border and Coast Guard'. Het promotieonderzoek is begeleid door promotoren prof.dr. P. Rodrigues en prof.dr. L. Besselink (UvA).

Identification of the products or product groups that have the greatest environmental impact from a life-cycle perspective using environmentally extended input-output analysis.

Promotor: Prof.dr. M.T.M. Koper, Co-Promotor: F. Calle-Vallejo

Promotor: Prof.dr. W.J.G.M. Peijnenburg

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Development of an aggregated impact indicator to measure decoupling.

Sobral

Patients share valuable advice and experiences with their peers in online patient discussion groups.

Promotor: A.P.IJzerman Co-promotor: A. Bender

Promotor: Prof.dr. A.G.G.M. Tielens

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

Promotor: Prof.dr. E. Bouwman

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Op 16 december 2019 verdedigde Jan-Harm de Villiers zijn proefschrift 'The Anthropomorphic Hegemony of Subjectivity: Critical Reflections on Law and the Question of the Animal'. Het promotieonderzoek is begeleid door promotor prof.dr. P. Cliteur.

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

The Sun and all the stars in the night sky reside in the Milky Way galaxy. In the at-rest reference frame of the Galaxy, typical stars travel with velocities of about 100-200 kilometres per second.

In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.

This dissertation is part of a broader research project that revolves around unraveling the evolution of balanced lethal systems.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Promotor: Prof.dr. M. Ubbink

The expanding population and economic activity are driving up global energy consumption. Simultaneously, there is an urgent need to transition from fossil fuels to renewable sources to mitigate the climate crisis, primarily caused by fossil fuel combustion.

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.