Hoe kunnen we onze maatschappij zo inrichten dat de wereld leefbaar blijft voor onszelf en al het andere leven om ons heen? Aan dat vraagstuk werken Leidse wetenschappers samen vanuit allerlei disciplines, van biologie tot datawetenschap en van milieueconomie tot archeologie.

This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

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GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.

Carbonaceous asteroids preserve a record of early solar system processes, where minerals and organic molecules, like polycyclic aromatic hydrocarbons (PAHs), offer clues to planetary evolution and prebiotic chemistry.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

The radio sky harbours both galactic and extragalactic sources of arcminute- to degree-scale emission of various physical origins. To discover extragalactic diffuse emission in the Cosmic Web beyond galaxy clusters, one must image low–surface brightness structures amidst a sea of brighter compact fore-…

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

In this thesis we investigate cosmology and the large scale structure of the Universe using cosmological simulations.

Promotor: Prof.dr. E. Deprettere

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

Promotor: W. Jiskoot, Co-promotor: H.A. Every

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

I have studied the hot, diffuse gas around and between galaxies. Specifically, I have used the EAGLE numerical simulations of galaxy formation to predict the properties of this gas, and I have used those properties to predict specific observables: soft X-ray absorption and emission lines.

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.

This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

Single-layer graphene (SLG) has attracted considerable interest as a proton exchange membrane for direct methanol fuel cells (DMFCs), owing to its atomic thickness, mechanical robustness, and unique proton permeability.

Endothelial dysfunction and microvascular diseases are key drivers of cardiovascular disease, the world's leading cause of death.

Cardiovascular disease is the leading cause of death worldwide.

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

Promotor: Roeland M.H. Merks

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Promotores: S.F. Portegies Zwart, E. M. Rossi

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

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Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.

Workshop

In 2050 moet de overstap naar nieuwe, duurzame energiebronnen zijn voltooid. Wetenschappers van de Universiteit Leiden verrichten vanuit diverse disciplines uniek onderzoek dat bijdraagt aan deze transitie en de reductie van CO2.

De Filmclub is een subvereniging van ProParte.

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