From 29 – 31 May, second-year students of the Advanced MSc in International Relations and Diplomacy (MIRD) took part in the programme's annual visit to Geneva, Switzerland. Students participated in various institutional visits, and got to hear first-hand from practitioners and experts on a variety of…

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

From 25-27 March, second-year students of the Advanced MSc in International Relations and Diplomacy (MIRD) took part in the programme's annual visit to Geneva, Switzerland. Students participated in institutional visits focusing on a wide range mandates in the field of International Relations and Dip…

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotie

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

In this thesis, I investigated the neurogenetic properties of Neotropical bat species. Bats represent the second largest mammalian order (Chiroptera) in the world, with Neotropical bats constituting about 13% of the total number of bat species.

The field of science communication is very broad. Below is a list of organisations where SCS students can fulfill internships or where alumni have found jobs.

Promotie

Promotie

De specialisatie International Relations and Organisations geniet een grote populariteit. Om de kwaliteit van het onderwijs te waarborgen, is het aantal studenten dat wordt toegelaten beperkt. Dit staat bekend als een ‘numerus fixus’.

Je gaat specifieke vakken volgen zoals International Organisations en Actors in World Politics. Maar je verdiept je ook in meer algemene thema’s, zoals International Politics, Comparative Politics en Global History. Ook werk je aan je academische en professionele vaardigheden.

Als je International Relations and Organisations studeert, lijkt het alsof de tijd vliegt. Gelukkig geeft deze specialisatie je een ideale basis voor een vervolgopleiding en een professionele carrière.

Heb je een vraag over het studentenleven Den Haag, studeren aan de Universiteit Leiden of wil je meer informatie over International Relations and Organisations? Je kunt direct in contact komen met een student!

Dit onderzoekscluster maakt deel uit van het onderzoeksprogramma ‘Institutions, Decisions and Collective Behaviour’.

Deze onderzoekscluster maakt deel uit van het onderzoeksprogramma ‘Institutions, Decisions and Collective Behaviour’.

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.

Supervisor: P.J.J. Hooykaas

This dissertation is part of a broader research project that revolves around unraveling the evolution of balanced lethal systems.

The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

The AT-Hook Nuclear Localized 15 (AHL15) gene belongs to a plant-specific gene family of DNA-binding proteins. Overexpression of AHL15 in Arabidopsis thaliana delays developmental phase transitions whereas its loss of function causes a slight acceleration.

Understanding DNA repair mechanisms is essential for advancing plant biotechnology and crop improvement. This study investigates how double-strand breaks (DSBs), induced by CRISPR/Cas systems, are repaired in the model plant Arabidopsis thaliana, and how these processes influence Agrobacterium tumefaciens…

Heb je een vraag over studeren aan de Universiteit Leiden? Of over de specialisatie International Relations and Organisations? Neem gerust contact met ons op!

Politicologie is een brede studie met veel diepgang. Je bestudeert politieke vraagstukken op lokaal, nationaal en internationaal niveau, vanuit verschillende invalshoeken.

Promotie

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

Promotores: H. Schiessel, G.T. Barkema

Festival

Festival