Mariëlle Bruning, hoogleraar jeugdrecht, is namens Nederland verkozen tot lid van de Expert Group Responses to violence against children (CAHENF-VAC) welke is opgezet om de Ad Hoc Committee for the Rights of the Child (CAHENF) van de Raad van Europa te assisteren.

Sinds oktober 2024 is Jannemieke Ouwerkerk, hoogleraar Europees Strafrecht, toegetreden tot de Expert Group on EU Criminal Policy van de Europese Commissie (EC). Deze onafhankelijke adviesgroep richt zich op het versterken van coherentie en consistentie van het EU-strafrechtbeleid.

Simone van der Hof, hoogleraar Recht en Digitale Technologie bij eLaw, is als expert toegetreden tot de EU Special Group on Code of Conduct for age-appropriate design.

Promotor: H.W. Lenstra

Hoogleraar Financieel Recht Matthias Haentjens is recent benoemd tot lid van een Expert Group van de Europese Commissie over een Europees stelsel van conflictregels ten aanzien van effecten en vorderingen. Deze deskundigengroep heeft tot doel het bijstaan van de Commissie in haar werk om te komen tot…

In het huidige systeem worden veel taken en rollen ondergewaardeerd.

In this thesis integral points on affine del Pezzo surfaces are studied.

Promotores: S.J. Edixhoven, F. Andreatta

Vandaag de dag liggen statistische methodes aan de grondslag van beslissingen in allerlei facetten van het leven, van de gezondheidszorg en agricultuur tot de financiële sector en marketing.

Promotor: R. Gill, Co-promotor: P. Massart

This thesis contains results on the arithmetic and geometry of del Pezzo surfaces of degree 1.In Chapter 1 we give the necessary background, assuming the reader is familiar with algebraic geometry.

Promotor: Bas Edixhoven, Promotor: Qing Liu

Despite their ecological, cultural, and economic importance, lion (Panthera leo) populations in Kenya are declining rapidly due to retaliatory killings following livestock depredation, depletion of wild prey, habitat loss driven by human activities, climate change, and disease.

This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.

Inspired by natural photosynthesis, perovskite-based photoelectrochemical (PEC) systems are being developed for artificial photosynthesis, aiming to enhance solar-to-hydrogen conversion for green energy.

Didactiek

In this thesis, we explore a Hochschild homology and cohomology-like notion for logarithmic schemes.

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.

Webinar with Q&A

The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.

Promotor: S.J. Edixhoven, L.D.J. Taelman

We show that Kirchhoff ’s law of conservation holds for non-commutative graph flows if and only if the graph is planar. We generalize the theory of (Euclidean) lattices to infinite dimension and consider the ring of algebraic integers as such a lattice.

Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…

The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Promotor: J. Zaanen

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

Lees waar je als student van de Universiteit Leiden terecht kunt voor steun als je die nodig hebt en welke afspraken er gelden voor sociale veiligheid in de online leeromgeving.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

Promotor: S.J. Edixhoven Co-promotor: L. van Geemen, P. Parent

N-acylethanolamines (NAEs), including N-arachidonoylethanolamine (anandamide, AEA), N-palmitoylethanolamine (PEA) and N-oleoylethanolamine (OEA), are signaling lipids that play an important role in different physiological process.

In het academisch jaar 2023-2024 biedt het interdisciplinaire onderzoeksprogramma Sociale Veerkracht en Veiligheid vier vakken aan voor studenten die beginnen met het derde jaar van hun bachelor. Deze vakken zijn te volgen binnen de ruimte voor keuzevakken. Je kunt de vakken afzonderlijk als keuzevak…

OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

De Declaration of equity helpt studieverenigingen op het gebied van diversiteit en inclusie.

Promotor: P.M. Brakefield

Onderzoeken en ontwerpen worden steeds belangrijker in het internationale bètaonderwijs. In Nederland zijn onlangs de nieuwe vakken O&O (onderzoeken en ontwerpen) en NLT (natuur, leven en technologie) ingevoerd, die aandacht besteden aan onderzoeks- en ontwerpopdrachten in de klas. In dit onderzoek…

Steeds meer scholen bieden tweetalig onderwijs aan. Het doel van dit project is het verder ontwikkelen van de manier waarop tweetalig onderwijs wordt gegeven, en zo het leren door leerlingen te bevorderen.

Cruciale informatie over onderzoek, financiering of de totstandkoming van universitaire ranglijsten is vaak niet vrij toegankelijk. De Barcelona Declaration on Open Research Information roept op dit soort informatie openbaar te maken. Hoogleraar Ludo Waltman is een van de initiatiefnemers. Wat moet…

Samen met wetenschappers van over de hele wereld streeft de ENIGMA-Anxiety Werkgroep ernaar om meer inzicht te krijgen in de neurobiologische karakteristieken van angststoornissen.

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Big Science, commonly defined as conventional science made big in three dimensions, namely organizations, machines, and politics, brings a plethora of different stakeholders together, often for a long period of time. This includes policymakers, scientists, (scientific) managers as well as local “host”…

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Diacylglycerol lipases (DAGLα and DAGLβ) are responsible for the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the brain and peripheral tissues. Selective DAGLβ inhibitors have been proposed as a potential treatment for inflammatory diseases with reduced potential for central…