Studievoorlichting

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In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

CMLCA is a software tool that supports the technical steps of the Life Cycle Assessment. The focus of the program is on advanced computational aspects of life cycle inventory calculations.

In the traditional theory of linear elasticity, superposition dictates that the response of a material does not depend on the sequence of the applied mechanical actuations.

The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.

Promotor: Prof.dr. J.P. Abrahams

The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

Dit deelproject pleit voor een nauwkeurige en forensische reconstructie van de financiële stromen van en naar de Sovjetrepublieken in Centraal-Azië in de naoorlogse periode.

Are you interested in studying Data Science & Artificial Intelligence in Leiden? Would you like to know more about this Bachelor programme at Leiden University? Do you have some last questions that only a student can answer? Then sign up for the Experience Day!

This thesis explores squaramide-based supramolecular polymers and hydrogels, enhancing their mechanical strength for 3D cell culture.

Studievoorlichting

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Computational thinking, programming, and algorithms form the basic of many of the things that are shaping our world, the way we work, interact, organize ourselves, and even spend our free time with social networks, streaming media, and games. And this transformation is far from being complete, it is…

Kunst en vrije tijd, Kunst en vrije tijd

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Carbonaceous asteroids preserve a record of early solar system processes, where minerals and organic molecules, like polycyclic aromatic hydrocarbons (PAHs), offer clues to planetary evolution and prebiotic chemistry.

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

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Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.

Planets are formed in disks of gas and dust around young stars.

Leiden en De Haag zijn echte studentensteden met een sfeervol en compact centrum waar je alles vindt wat je als master student nodig hebt.

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

Catharanthus roseus (Madagascar periwinkle) produces valuable monoterpenoid indole alkaloids (MIAs) such as vincristine and vinblastine, crucial for cancer treatment.

Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.

Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.

Single-layer graphene (SLG) has attracted considerable interest as a proton exchange membrane for direct methanol fuel cells (DMFCs), owing to its atomic thickness, mechanical robustness, and unique proton permeability.

This dissertation explores new chemical strategies for the synthesis of self-adjuvanting peptide conjugates and immunomodulatory ligands aimed at targeted activation of the immune system.

This thesis advances our understanding of lipid uptake, a vital first step in lipid metabolism, by developing innovative click chemistry-based tools to study how immune cells internalize lipids.

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.