164 zoekresultaten voor “soil barbiers repair” in de Publieke website
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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The Ecology and Evolution of Microbial Warfare in Streptomyces
The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.
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Development of life cycle assessment for residue-based bioenergy
Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs
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Life In Plastic, Not Always Fantastic: Nano- and microplastics and their impact on terrestrial plants and the food chain
Plastics have become an integral part of modern society due to their versatility and durability.
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Vaksteunpunten Nederlands en Moderne Vreemde Talen
Vaksteunpunten Nederlands en Moderne vreemde talen
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Micro-leven bij biologische en gangbare melkveebedrijven voor het eerst in kaart gebracht
Elk onderdeel van de kringloop op een melkveebedrijf heeft een specifieke bacterie- en schimmelsamenstelling. Dat ontdekten de Leidse postdoc onderzoeker Sofia Gomes en haar begeleiders Nadia Soudzilovskaia en Peter van Bodegom in samenwerking met het Louis Bolk instituut en Naturalis Biodiversity Centre.…
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Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.
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Elective Abdominal Aneurysm Repair Challenges remain
Promotie
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Enhancing epicardial EMT to repair the heart
Promotie
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Computationele taalkunde
Binnen de computationele taalkunde wordt er gebruik gemaakt van computermethodes om antwoord te krijgen op taalkundige vragen over verscheidene onderwerpen.
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Theoretische taalkunde
Onderzoek naar de onderliggende principes van de menselijke taal.
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Syntaxis
Syntactici onderzoeken hoe woorden in de menselijke taal worden gecombineerd tot grotere eenheden (frases en zinnen) en hoe de combinatiemogelijkheden de woordvolgorde en de grammaticale relaties tussen de delen van een zin bepalen.
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotores: T.H. Oosterkamp, N. de Jonge
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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New dimensions of the cellular response to DNA damage
Thirty years ago, mutations in the BRCA1 gene were first linked to hereditary breast and ovarian cancer, establishing a genetic basis for cancer development.
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Machine learning and computer vision for urban drainage inspections
Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.
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Centre for Linguistics (LUCL)
Het Leiden University Centre for Linguistics (LUCL) is een van de instituten van de Faculteit Geesteswetenschappen.
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Centre for Digital Humanities
Het Leiden University Centre for Digital Humanities (LUCDH) is een interdisciplinair centrum dat studenten en medewerkers uit de hele Leidse gemeenschap samenbrengt.
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Understanding BRCA1(-complexes) in DNA repair and cancer
Promotie
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Advancements in Brushite cement formulations for bone repair
Promotie
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Branching Out: The Clinical Relevance of Mismatch Repair Variants
Promotie
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Control of replication associated DNA damage responses by Mismatch Repair
Promotie
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Exploring the chemical space of natural products from Streptomyces using multi-omics approaches
The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.
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Expanding the chemical space of antibiotics produced by Paenibacillus and Streptomyces
Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…
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The rhizomicrobiome of Sorghum ; impact on plant growth and stress tolerance
The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.
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Fire and grazers in the West African savanna
Promotores: H.A. Udo de Haes, H.H.T. Prins, Co-promotor: H.H. de Iongh
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Molecular characterization of copper-dependent enzymes involved in Streptomyces morphology
Promotor: G.P. van Wezel, Co-promotor: D. Claessen
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Cheating belowground interactions
Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.
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Functional xylem anatomy: intra and interspecific variation in stems of herbaceous and woody species
My PhD thesis investigates the ecological significance of resistance against drought-induced air bubble formation inside the water conduits of plants (embolism), and the plasticity and functional aspects of stem anatomical traits in woody and herbaceous species.
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Unsprayed field margins: effects on environment, biodiversity and agricultural practice
A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…
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Morphogenesis and heterogeneity in liquid-grown streptomyces cultures
The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.
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Impact of plant hormones on growth and development of actinobacteria
Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.
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Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
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Bestrijdingsmiddelen en Milieu
The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom
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Over de opleiding
De master Neerlandistiek geeft je ruime kennis van en inzicht in de inhoud van het vakgebied van jouw keuze.
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Pengxuan XieWiskunde en Natuurwetenschappen
p.xie@cml.leidenuniv.nl | +31 71 527 2727
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Organisatie
Het Leiden University Centre for Linguistics (LUCL) is een onafhankelijk instituut binnen de Faculteit der Geesteswetenschappen van de Universiteit Leiden. Een management team, bestaande uit een wetenschappelijk directeur, een onderwijsdirecteur en een instituutsmanager, is verantwoordelijk voor de…
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Farzad AslaniWiskunde en Natuurwetenschappen
f.aslani@biology.leidenuniv.nl | +31 71 527 2727
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SMALL Savannah : an information system for the integrated analysis of land use change in the Far North of Cameroon
Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan
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Doe mee aan ons onderzoek naar betere zorg voor depressieve jongeren
De vier Leidse promovendi Loes Janssen, Mirjam Wever, Dianne van der Heide en Lisanne van Houtum werken mee aan onderzoek om depressieve jongeren te helpen met een betere diagnostiek. Doe je mee? Ook ouders van jongeren zonder psychische klachten zijn welkom.
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Onze mensen
Dit zijn de mensen die binnen de Universiteit Leiden actief zijn op het gebied van kunstmatige intelligentie.
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Na je studie
En dan ben je afgestudeerd! Als film- en literatuurwetenschapper heb je kennis van verschillende culturen en media. Je weet hoe je tekst en beeld kunt ‘lezen’. Bovendien ben je een onafhankelijke, kritische denker en onderzoeker. Dat maakt je geschikt voor veel verschillende functies.
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Martijn LemmenFaculteit der Geesteswetenschappen
m.m.m.a.lemmen@hum.leidenuniv.nl | 071 5272727