The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

De eerste eLaw Conferentie was een succes en stimuleerde actuele discussies over de juridische uitdagingen en kansen die digitale technologieën met zich meebrengen.

IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Aylin Alexa Zainea heeft op 29 januari 2024 de scriptieprijs van de Autoriteit Persoonsgegevens gewonnen. Zij schreef haar scriptie binnen de Advanced Master opleiding Law and Digital Technologies van eLaw, het centrum voor recht en digitale technologie. Haar scriptie getiteld ‘Automated Decision-Making…

In opdracht van Tracks Inspector, een bedrijf dat innovatieve software ontwikkelt, doet eLaw onderzoek naar cyber agent technology voor inlichtingen- en veiligheidsdiensten.

Op vrijdag 10 december 2021 organiseerde eLaw - Centrum voor Recht en Digitale Technologie, haar jaarlijkse Research Colloquium. eLaw-promovendi en professoren gaven presentaties over een breed scala aan onderwerpen op het gebied van recht en digitale technologie, waaronder digitaal openbaar bestuur,…

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

Promotie

Privacy houdt de gemoederen voortdurend bezig: van MeToo tot Facebook. Het juridisch maandblad Ars Aequi heeft zijn Bijzonder Nummer 2019 gewijd aan privacy. Drie bijdragen komen vanuit eLaw, het centrum voor recht en digitale technologie van de Faculteit der Rechtsgeleerdheid.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

In January 2021, eLaw joined the Computers Privacy and Data Protection (CPDP) Conference that is about privacy and data protection. The group on Law and Digital Technologies at Leiden University put together a panel that combined perspectives on Art, Society, & Technology.

Van deepfakes en disinformatie tot killer robots, chirurgische robots en AI wetgeving: AI (Artificial Intelligence, kunstmatige intelligentie) verandert onze wereld. Dat roept de vraag op of enige vorm van regulering nodig is. Bij eLaw, het centrum voor recht en digitale technologie van de Universiteit…

Andreas Haüselmann en Eduard Fosch-Villaronga van eLaw – Centrum voor Recht en Digitale Technologie schreven een artikel over de juridische en regelgevende aspecten van data over emoties en presenteerden dit op de Affective Computing + Intelligent Interaction (ACII ’23)-conferentie bij MIT. Andreas…

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

With the conference circuit slowly reopening after Covid forced almost all academic interactions online, thousands of conference attendees descended on Brussels for Europe’s largest technology conference. eLaw’s annual sponsorship of one of the many CPDP conference panels brought a diverse range of…

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

This thesis seeks to investigate how cancer-associated mutations affect the pharmacological properties of selected GPCRs—primarily A2AAR and 5-HT2CR—through a combination of ligand binding assays, signaling readouts, kinetic profiling, and cellular functional assays.

Op 26 en 27 september namen Eduard Fosch-Villaronga, Carlotta Rigotti, Mohammed Raiz Shaffique, Marie Schwed-Shenker en Antoni Mut Piña deel aan de derde editie van Lawtomation Days aan de IE University in Madrid.

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Vanaf de koloniale tijd tot heden hebben grote aantallen Javanen hun woonplaats verlaten om zich in andere delen van Indonesië of veel verder weg te vestigen. Vaak was deze spreiding gedwongen, vaak met traumatische gevolgen.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

This dissertation presents new cryptographic protocols, which can be divided into two families.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

In dit artikel onderzoeken Thijs van Dooremalen en Philip Smith hoe het publieke discours over hittegolven is verschoven in Britse kranten.

Op woensdag 6 maart ontvangt eLaw - Center for Law and Digital Technologies Prof.dr. Margot Kaminski, een eminent wetenschapper van Colorado Law School. Kaminski gaat tijdens een onderzoeksochtend haar nieuwe paper over Participatory Data Governance presenteren, die ze samen met dr. Gianclaudio Malgieri,…