This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Hydrogen fuel cells are expected to be pivotal in the energetic transition towards renewable energy sources such as solar and wind power. However, their industrial scalability is severely hindered by the high cost and degradation rate of platinum catalysts, one of their key components. Addressing this…

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

Promotor: Prof.dr. J. den Hertog

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

Promotor: H.W. Lenstra

Anthropogenic noise has been shown to affect marine animals in various ways, this may have fitness consequences at individual and population level. This thesis aims to increase insight into the quantification of sound-induced behavioural responses that are relevant to fitness, and into factors that…

Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

Microbiome composition of the spermosphere and the rhizosphere of wild and modern bean accessions grown in an agricultural and a native soil from Colombia was characterized by metagenomics and cultivation-dependent approaches.

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Surface plasmons (SPs) are surface waves at the interface between a dielectric and a good metal, and are formed by the interaction between light and the free electrons at the metal-dielectric interface. They provide strong field confinement for optical fields, opening new possibilities for enhanced…

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

Let A be a commutative algebraic group over a field K, and let G be a finitely generated subgroup of the K-rational points of A. The purpose of this thesis is to study the degrees of the Kummer extensions relative to A,K and G.

This thesis focuses on the social dimensions of crane and wetland conservation in rural landscapes in Kenya, Uganda and Zimbabwe.

The goal of the research presented in this thesis was to explore the chemical space of ruthenium(II) photocages, investigate their ability to host potent chemotherapy drugs, and to red shift the activation wavelength of the most promising PACT candidates to conduct biological studies.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

Promotor: B.van de Water, Co-promotor: L.S.Price

LLInC ondersteunt innovatief en hoogwaardig onderwijs, binnen de Universiteit Leiden en in samenwerking met onderwijs- en maatschappelijke organisaties.

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

Humans perceive the real world through their sensory organs: vision, taste, hearing, smell, and touch. In terms of information, we consider these different modesalso referred to as different channels of information or modals.

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

Promotores: G.W. Canters, T.J. Aartsma

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

Including modelling as part of software development appears to have various benefits.

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

Promotor: Prof.dr. C.W.J. Beenakker

Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Single-layer graphene (SLG) has attracted considerable interest as a proton exchange membrane for direct methanol fuel cells (DMFCs), owing to its atomic thickness, mechanical robustness, and unique proton permeability.

This thesis investigates reactive interfaces in surface science across three domains: heterogeneous catalysis, environmental nanoplastics, and two-dimensional materials.

Het HOVO van de Universiteit Leiden biedt colleges op universitair niveau voor mensen met vijftig jaar levenservaring. Er zijn collegereeksen op het gebied van de geesteswetenschappen, de sociale wetenschappen en de natuurwetenschappen. Het programma van colleges kunt u vinden onder Collegeaanbod

Een docent moet zich terughoudend opstellen, zodat er meer ruimte is voor discussie tussen studenten. Dat vindt celbioloog Roeland Dirks. De bevlogen docent is genomineerd voor de LUS Onderwijsprijs.

Studenten die meedoen aan 'StudentinzetopSchool' helpen scholieren en doen tegelijkertijd zelf waardevolle onderwijservaring op. In een digitaal werkbezoek op 13 april ging koningin Máxima in gesprek met scholieren, studenten en onderwijsmedewerkers. Ze sprak ook met Leidse deelnemers. ‘Lesgeven is…

In de documentaire Pretend Student vertellen voormalige studenten waarom ze iedereen lieten geloven dat ze nog steeds studeerden. Hoe kun je voorkomen dat je in zo’n onmogelijke situatie terechtkomt? Vier vragen aan de Leidse studentendecaan Romke Biagioni die ook meewerkte aan de documentaire.

Van ‘challenges’ op ministeries tot reflectiesessies waarin studenten elkaar coachen. Studenten, studieadviseurs en andere medewerkers deelden hun best practices ten aanzien van arbeidsmarktvoorbereiding op de werkconferentie Employability op 24 januari.