999 zoekresultaten voor “e could” in de Publieke website
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Assembling anisotropic colloidal building blocks
This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Musems, Collections and Society | Yearbook 2021
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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Osteosarcoma: searching for new treatment options
Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen
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Multiple star formation: chemistry, physics and coevality
Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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Small changes for long term impact: optimization of structure kinetic properties: a case of CCR2 antagonists
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Magnetic imaging of spin waves and magnetic phase transitions with nitrogen-vacancy centers in diamond
The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.
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Potential interference of fungal endophytes in Vanilla planifolia on vanilla flavor compounds biosynthesis
Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.
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Safe anytime-valid inference: from theory to implementation in psychiatry research
Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.
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Tuning in to star-planet interactions at radio wavelengths
Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.
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The architects of crenarchaeal chromatin: A biophysical characterization of chromatin proteins from Sulfolobus solfataricus
Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame
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Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
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Ecological functions and environmental fate of exopolymers of Acidobacteria
Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.
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Non-invasive biomarkers for inflammatory skin diseases: towards systems dermatology
Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…
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Shining Light on Interstellar Matter
Promotor: H.V.J. Linnartz
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Learning from nature: using plant-soil feedback principles to improve growth and health of a horticultural crop
Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…
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Unraveling multifaceted roles of Grainyhead-like transcription factor-2 in breast cancer
Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.
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Towards a Circular Food System: Global Resource Losses, Waste Typologies, and Valorization Pathways
Food waste is a defining inefficiency of the modern food system, with profound implications for resource use, climate change, and circular economy transitions. This dissertation examines food waste through two complementary lenses: the prevention of avoidable food waste and the valorization of unavoidable…
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Insights from scanning tunneling microscopy experiments into correlated electron systems
This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Applications of Natural Deep Eutectic Solvents to Extraction and Preservation of Biomolecules
The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.
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Learning in Automated Negotiation
This dissertation advances automated negotiation by developing agents that can learn and adapt across diverse negotiation settings through three increasingly sophisticated approaches: automated algorithm configuration, portfolio-based strategy selection, and end-to-end reinforcement learning with graph…
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Empirical Legal Studies Leiden
Empirical Legal Studies in Leiden focuste op het bouwen van een interdisciplinaire gemeenschap van rechtsgeleerden en sociale wetenschappers die samen juridische vraagstukken onderzochten op het snijpunt van recht en gedrag, waarbij diverse soorten methoden werden gebruikt.
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A European Ministry of Finance?
Op 21 oktober 2021 verdedigde Frederik Behre het proefschrift 'A European Ministry of Finance?'. Het promotieonderzoek is begeleid door promotor prof.dr. S.C.G. Van den Bogaert.
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Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches
Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.
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Open label placebo voor jeuk
Positieve verwachtingen kunnen het gevoel van jeuk beïnvloeden en placebo-effecten oproepen, terwijl negatieve verwachtingen nocebo-effecten bij jeuk kunnen veroorzaken. Er zijn aanwijzingen dat placebo-effecten ook kunnen optreden wanneer mensen weten dat zij een placebo innemen. Er is weinig bekend…
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Publicaties
Disclaimer: Manuscripten die te maken hebben met het Resilience Center zijn alleen voor academische doeleinden en zijn niet bedoeld voor massaverspreiding of kopiëren. Raadpleeg de toepasselijke wetten voor eerlijk gebruik, inclusief de beperkingen van de houders van auteursrechten op publicaties.
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Coherent Privaatrecht
Is het privaatrecht klaar voor de uitdagingen van deze tijd?
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Publicaties
Het team van het Hazelhoff Centre for Financial Law publiceert regelmatig in zowel Nederlandse als internationale wetenschappelijke tijdschriften en boekreeksen.
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The Progression of EU Law: Accommodating change and upholding values
Wat is de institutionele dynamiek van de goedkeuring van wetgeving inzake de interne markt?
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Effective Protection of Fundamental Rights in a pluralist world
Welke kansen en bedreigingen vloeien voort uit de institutionele en normatieve diversiteit op het terrein van de rechten van de mens voor de effectieve bescherming van die rechten in een wereld die gekenmerkt wordt door pluralisme?
- Publicaties
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Positive representations of algebras of continuous functions
If X is a locally compact Hausdorff space, then a representation of the complex C* algebra C_0(X) on a Hilbert space $H$ is given by a spectral measure that takes its values in the orthogonal projections on $H$.
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De Decreta van de Romeinse jurist Julius Paulus
Hoe zag de keizerlijke rechtsbedeling en gerechtelijke oordeelsvorming onder de Severische keizers eruit?
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Contact
Het secretariaat (kamer 2B07) wordt bemenst door Eva Potters en Pauline Ruygrok
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Nanodeeltjes – redox eiwit biohybriden
Kunstmatige fotosynthese heeft als doel om via chemische processen zonne-energie om te zettn in brandstof. Semi-kunstmatige fotosynthese is een hybride aanpak waarbij chemische maar ook biotechnologische processen worden gebruikt. Wij hebben als doel om een hybride systeem te ontwikkelen met behulp…
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Onderwijs- en organisatieontwikkeling
Publicaties Onderwijs- en organisatieontwikkeling
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Exploring the Frontiers of International Law
Dit onderzoeksprogramma brengt door het verkennen van de grenzen van het internationaal publiekrecht deze verandering van de internationale rechtsorde in kaart.
- Leden (gerangschikt per universiteit en categorie)
- Publicaties
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Internship information
An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.
- Organisatie
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Health Governance
Groeiende gezondheidsverschillen, toenemende zorgkosten, de vergrijzing en het tekort aan zorgpersoneel zijn slechts enkele voorbeelden van uitdagingen waar de gezondheidszorg voor staat, zowel in Nederland als daarbuiten. Deze vraagstukken overstijgen de grenzen van de medische sector en raken aan…
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Onderzoek
Onderzoek dat binnen het instituut wordt uitgevoerd valt onder het onderzoeksprogramma Criminal Justice: Legitimacy, Accountability and Effectivity. In dit onderzoeksprogramma werken (strafrecht)juristen en sociaal wetenschappers, in het bijzonder criminologen, nauw samen.
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Criminal Justice: Maatschappelijk effectieve strafrechtspleging 2023-2029
Criminal Justice Onderzoeksprogramma van het Instituut voor Strafrecht en Criminologie
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Biomarkers in Duchenne and Becker muscular dystrophy
Promotie
- Publicaties