1,378 zoekresultaten voor “immune systems” in de Publieke website
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Getting the electrons right for O2-on-metal systems
Dit proefschrift gaat over theoretische oppervlakte chemie binnen het veld van de heterogene katalyse.
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Large Time Behaviour of Neutral Delay Systems
Promotor: S.M. Verduyn Lunel
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Photo-activated drug delivery systems
O-Nitrobenzyl groepen worden veel gebruikt als moleculaire beschermgroepen die je met licht kunt verwijderen.
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Life cycle assessment of emerging chemical technology systems: challenges and future needs
The upscaling of Life Cycle Assessment (LCA) data is recognized as one of the main challenges in the ex-ante LCA of emerging technologies. This challenge arises since industrial-scale system specifications for these technologies are unknown and industrial data is lacking.
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Young suns and infant planets: Probing the origins of solar systems
Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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The Interactions of Human Mobility and Farming Systems and Impacts on Biodiversity and Soil Quality in the Western Highlands of Cameroon
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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and Cosmetic (MAC) Plants in the Utilisation of the Plural Medical System in Pirgos and Praitoria for Community Health Development in Rural Crete
Promotor: Prof.dr. L.J. Slikkerveer
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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Handbook of Signal Processing Systems
Handbook of Signal Processing Systems is organized in four parts. The first part motivates representative applications that drive and apply state-of-the art methods for design and implementation of signal processing systems; the second part discusses architectures for implementing these applications;…
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Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems
Op 14 november 2019 verdedigde Luis Fiallos Pazmino zijn proefschrift 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. Het promotieonderzoek is begeleid door promotoren prof.dr. P.M.J. Mendes de Leon en prof.dr. E.C.P.D.C. De Brabandere.
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Low-Energy Electron Microscopy on Two-Dimensional Systems: Growth, Potentiometry and Band Structure Mapping
Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp
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engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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sustainability of NdFeB magnet recycling: foresight study on recycling systems and technologies
The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.
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Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification
Op 29 januari 2019 verdedigde Robbert van Eijk proefschrift 'Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification'. Het promotieonderzoek is begeleid door promotor prof. dr. H.J. van den Herik.
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Lipid nanoparticle technology for mRNA delivery: Bridging vaccine applications with fundamental insights into nano-bio interactions
Lipid nanoparticles (LNPs) have enabled the success of mRNA vaccines but remain limited in broader therapeutic use by challenges in delivery efficiency, targeting, and mechanistic understanding.
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FAIRDOM – FAIR Sharing for Systems and Synthetic Biology
Het FAIRDOM-consortium is een open initiatief van verschillende partners, waaronder financieringsprogramma's, grote consortia, instituten, kleine groepen en individuen.
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Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design
Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.
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The role and analysis of molecular systems in electrocatalysis
Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.
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Interaction with sound for participatory systems and data sonification
This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.
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Civil Liability for Damage caused by Global Navigation Satellite System
Op 17 december 2018 verdedigde Dejian Kong zijn proefschrift 'Civil Liability for Damage caused by Global Navigation Satellite System'. Het promotieonderzoek is begeleid door promotor prof. dr. P.M.J. Mendes de Leon.
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Silicon pore optics for high-energy optical systems
This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.
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scanning tunneling microscopy experiments into correlated electron systems
This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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Sukamiskin: Utilisation of the Plural Health Information and Communication System in the Sunda Region of West Java, Indonesia
This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.
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Engineering of antigen-saving dissolving microneedles for intradermal vaccine delivery
The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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tanks in a consensus – seeking and neo-corporatist policy advisory system
In dit artikel leveren Bert Fraussen en Valérie Pattyn een theoretische bijdrage aan de bestaande literatuur over beleidsadvies door zich te laten inspireren door de nichetheorie.
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policy-making; the contribution of think tanks to policy advisory systems
In de afgelopen drie decennia is er een sterke toename van het aantal denktanks in de meeste westerse democratieën, waarbij zij steeds meer gezien worden als belangrijke spelers in beleidsprocessen. Toch blijft hun precieze bijdrage aan beleidsvorming gecontesteerd.
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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System-level design for efficient execution of CNNs at the edge
A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Overlapping institutions in the UN human rights system: Mutually strengthening or undermining?
In dit artikel onderzoekt Valentina Carraro de relatie tussen overlappende VN-mensenrechteninstellingen, met name de verdragsorganen en de Universal Periodic Review (UPR).
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Development of a academic monitoring system for students with learning problems in secondary school
Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years
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characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
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The spin evolution of accreting and radio pulsars in binary systems
Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.
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β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste
Op 24 september 2020 verdedigde Bernardo Ribeiro de Almeida zijn proefschrift 'Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.
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Measuring sustainability: an elaboration and application of the system of environmental-economic accounting for Indonesia
Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…
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for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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Non-invasive biomarkers for inflammatory skin diseases: towards systems dermatology
Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…
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Tools for real-time study of bioorthogonal conversions in the living system
Traditional biochemical methods for studying organelles require cell disruption, preventing the real-time observation of dynamic intracellular processes.
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Immuniteit, Infectie en Tolerantie
Het immuunsysteem beschermt ons tegen ziekten, maar soms gaat het mis. Dan dringt er toch een vijand binnen of valt het immuunsysteem ons eigen lichaam aan, waardoor we ziek worden. Artsen en onderzoekers van het Leids Universitair Medisch Centrum (LUMC) willen het immuunsysteem zodanig sturen, dat…
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Parallel Worlds
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