1,146 zoekresultaten voor “s make” in de Publieke website
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Signalling pathways that control development and antibiotic production in streptomyces
Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.
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The synthesis of mannose-derived bioconjugates and enzyme inhibitors
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: J.D.C. Codee
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Electroextraction approaches for preconcentration of metabolites
In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.
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Chemistry and Biotechnology for Sustainability
If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…
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Sofia Express
In Sofia Express gaat Jan Paul Hinrichs op zoek naar de literaire geheimen van de Bulgaarse hoofdstad Sofia, een stad waarin detectives, spionage en andere intriges nooit ver weg zijn.
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Wat zit er achter het scherm? Verwachtingen van baby's van 10 maanden over verborgen voorwerpen
Het begrijpen van de wereld om ons heen hangt af van het vermogen om de wereld te ontleden in verschillende objecten en deze in hun geheugen op te slaan. Dit proces wordt gedefinieerd als object individuatie. Onderzoek wijst uit dat dit voor baby’s niet altijd gemakkelijk is.
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Beoordeling van troostend gedrag door twaalf maanden oude baby's: een keuze-experiment
Als mensen hebben we de neiging om bepaalde handelingen als goed of fout te beoordelen. Waar komt ons morele besef vandaan? We hebben bewijs gevonden dat baby's van slechts één jaar oud de voorkeur geven aan degenen die troosten in plaats van negeren wanneer iemand verdrietig is.
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Rationally designed peptide based functional biomaterials
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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AI in beeld - Mogelijkheden, risico’s en richtlijnen van kunstmatige intelligentie voor de beeldende journalistiek
Met AI kunnen nieuwsredacties razendsnel beelden genereren — maar tegen welke prijs? Dit onderzoeksrapport opgesteld door prof. dr. Jaap de Jong, dr. Astrid Vandendaele, Maartje van der Woude en Stef Arends (Universiteit Leiden), baseert zich op 59 interviews met beeldmakers, redacteurs en experts uit…
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Electrical and magnetic properties of ferritin: electron transport phenomena and electron paramagnetic resonance
Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Beweegprogramma’s voor patiënten met hart- en vaatziekten, gebaseerd op sociale beloningen
Bevordering van duurzame fysieke activiteit door middel van het betrekken van de sociale omgeving in beweeginterventies voor diverse patiëntgroepen met cardiovasculaire aandoeningen.
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Magnetic Resonance Force Microscopy and the Spin Bath
There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.
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Automata-theoretic protocol programming
Promotor: F. Arbab
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Orion's Dragon and Other Stories
Stellar feedback is a crucial ingredient in the evolution of galaxies.
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Children’s Rights in International Commercial Surrogacy
Op 26 juni 2018 verdedigde Claire Achmad haar proefschrift 'Children’s Rights in International Commercial Surrogacy: Exploring the Challenges from a Child Rights, Public International Law Perspective'. Het promotieonderzoek is begeleid door promotor prof. mr. drs. M.R. Bruning.
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Alumnidag L.P.S.V. „Aesculapius”
Alumni-activiteit
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Komt Goed: Appraisals, Coping en Stress van LIO's
Gevoelens en gedachten over jezelf als leerkracht spelen een hele belangrijke rol in de klas. Met dit onderzoek willen we meer inzicht krijgen in die gedachten en gevoelens. We kijken in de klas naar lessensituaties, waarbij we uitzoeken welke momenten stressvol zijn voor jullie, en welke gedachten…
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Picturing Intimacy: Mediation and Self-representation in a Boston’s Religious Festivals
Taking as a point of departure the Italian American community in Boston and its process of collective remembrance surrounding Saint Anthony’s Feast, we addressing the limits and potential of montage.
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Vergroten van Biodiversiteit op de Campus
Kijk regelmatig op deze pagina voor meer informatie over het vergroten van de biodiversiteit aan de Universiteit Leiden.
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Met een plakboek vol foto’s naar Leiden University College
Leiden University College bruist weer van leven. Op 13 augustus trok een nieuwe lichting studenten in hun studentenkamers. Voor meer dan tweehonderd eerstejaars is LUC de komende drie jaar hun thuis. Tijdens moving day spraken we drie van hen.
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Transacties met verbonden partijen (RPT's) en concerns in het Oekraïense ondernemingsrecht
Op 8 april 2020 heeft Ivan Romashchenko zijn proefschrift 'Related party transactions and corporate groups: When Eastern Europe meets the West' online verdedigd. Het promotieonderzoek is begeleid door prof. mr. S.M. Bartman en prof. A. Radwan.
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Transition metal compounds with S/N-functionalized NHC ligands: structures, redox properties and electrocatalytic activity
The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.
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Kaiser Wilhelm II’s Fridtjov: a foreign statue on a fjord. Nationalism, narcissism, and entertainment
Promotie
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Who’s still afraid of CRT? Equity research in education as resistance
Keynote & Q&A
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Menno SchilthuizenFaculteit der Wiskunde en Natuurwetenschappen
m.schilthuizen@biology.leidenuniv.nl | 071 5272727
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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Chemical Similarity: Structuring Risk and Hazard Assessment
At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.
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Better Predictions when Models are Wrong or Underspecified
Promotor: P.D. Grünwald
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Patterned detectors: From design to science
Patterned detectors are an existing technology that can be found in almost all color cameras.
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
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Exploring structure dependencies of gas-surface interactions with curved single crystals
Curved single crystals provide variable, but well-defined surface structures.
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The noisy underwater world: the effect of sound on behaviour of captive zebrafish
Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn
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Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Designing 'context-specific' regional innovation policy: a study on the role of regional government in six European regions
Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…
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Improving robustness of tomographic reconstruction methods
Promotor: Prof.dr. K.J. Batenburg
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Large scale visual search
Promotor: J.N. Kok, Co-promotor: M.S. Lew
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Spatio-temporal aspects of antigen cross-presentation in dendritic cells: with click-to-release chemistry
The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.
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Methods to simulate fermions on quantum computers with hardware limitations
This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.
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Solving the Gravitational N-body Problem with Machine Learning
In this work, I explore the creation of new methods that optimize simulations of the gravitational N-body problem. Specifically, I take advantage of the recent popularity of Machine Learning methods to find tools that can suit this problem.
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Semi-partitioned Scheduling and Task Migration in Dataflow Networks
Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov
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Substrate adaptability of β-lactamase
The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Principles of Environmental Sciences
Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…