Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

We prove a p-adic version of the work by Gross and Zagier on the differences between singular moduli by proving a set of conjectures by Giampietro and Darmon, who investigated the factorisation of a rational invariant associated to a pair of CM-points on a genus zero Shimura curve, obtained as the ratio…

In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.

Als mensen hebben we de neiging om bepaalde handelingen als goed of fout te beoordelen. Waar komt ons morele besef vandaan? We hebben bewijs gevonden dat baby's van slechts één jaar oud de voorkeur geven aan degenen die troosten in plaats van negeren wanneer iemand verdrietig is.

In the Schouwburgstraat, LUGO is currently redesigning the back-garden in order to increase biodiversity and make it a more beautiful space. Throughout October 2023 until March 2024, we will be making changes to the garden with our team of volunteers.

De masteropleiding International Organisation wordt aangeboden door de Universiteit Leiden in Den Haag. Op deze pagina wordt uitgelegd waarom studenten voor deze opleiding en locatie kiezen.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!

Met AI kunnen nieuwsredacties razendsnel beelden genereren — maar tegen welke prijs? Dit onderzoeksrapport opgesteld door prof. dr. Jaap de Jong, dr. Astrid Vandendaele, Maartje van der Woude en Stef Arends (Universiteit Leiden), baseert zich op 59 interviews met beeldmakers, redacteurs en experts uit…

Studievoorlichting, Experience Day

Elke week organiseert ISGA de Research Seminar Series waarin onderzoek van zowel medewerkers van ISGA als van externen aan bod komt.

The research profile ‘Asian Modernities and Traditions’ (AMT) aims to raise the strength and visibility of research, teaching and dissemination of Asian studies at Leiden University.

Bevordering van duurzame fysieke activiteit door middel van het betrekken van de sociale omgeving in beweeginterventies voor diverse patiëntgroepen met cardiovasculaire aandoeningen.

The ERC project Early Medieval English in Nineteenth-Century Europe (EMERGENCE), led by Thijs Porck (Leiden University) is hiring 1 postdoctoral researcher and 2 PhD's. Details on the individual projects can be found below. Deadline for applications: 1 March 2024.

Stellar feedback is a crucial ingredient in the evolution of galaxies.

Op 26 juni 2018 verdedigde Claire Achmad haar proefschrift 'Children’s Rights in International Commercial Surrogacy: Exploring the Challenges from a Child Rights, Public International Law Perspective'. Het promotieonderzoek is begeleid door promotor prof. mr. drs. M.R. Bruning.

EXIOBASE is a global, detailed Multi-regional Environmentally Extended Supply and Use / Input Output (MR EE SUT/IOT) database. It was developed by harmonizing and detailing SUT for a large number of countries, estimating emissions and resource extractions by industry, linking the country EE SUT via…

Donderdag 1 december 2016 is Francisco Sepulveda Ramirez gepromoveerd op zijn proefschrift 'Residence in Tax Treaties'. Zijn promotor was hoogleraar Belastingrecht Frank Engelen.

Discover "Meta Analysis" at Boerhaave Nascholing. Explore risk analysis, models, and advanced topics. Elevate your understanding. Read more here.

A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.

Samenlevingen wereldwijd worden geconfronteerd met grote uitdagingen, die voortkomen uit onder meer klimaatverandering, technologische innovaties en politieke en economische crises. In de master Public Administration (MSc) pak je deze vraagstukken aan vanuit een multilevel governance-perspectief.

In this thesis, single-cell approaches were applied to characterize the impact of aging on the immunological B cell landscape in different models of atherosclerotic cardiovascular disease, with the goal to identify and study new B cell-associated biomarkers and therapeutic targets to halt atherosclerosis…

Kunst en vrije tijd, Kunst en vrije tijd

Gevoelens en gedachten over jezelf als leerkracht spelen een hele belangrijke rol in de klas. Met dit onderzoek willen we meer inzicht krijgen in die gedachten en gevoelens. We kijken in de klas naar lessensituaties, waarbij we uitzoeken welke momenten stressvol zijn voor jullie, en welke gedachten…

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)

Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit

Galaxy intrinsic alignments induce a major astrophysical contamination to weak gravitational lensing measurements and need to be modelled and mitigated when extracting cosmological information from such measurements.

Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Obesity may alter how a person absorbs, distributes, metabolizes or excretes medication. This thesis describes how obesity affects drug levels in the blood for antimicrobial agents, such as ciprofloxacin and fluconazole.

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.

Natural resources often stretch across borders that separate modern nation states. This can create conflict and limit opportunities for regulated consumption of their goods and services, but also provide opportunities for joint multinational efforts that exceed single country capabilities.

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Promotor: M.L. van Hecke