Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.

Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L. Kaper (UvA)

In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

In this thesis we investigate cosmology and the large scale structure of the Universe using cosmological simulations.

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

Promotor: Prof.dr. H.J.A. Rottgering

Beneficial plant-associated microbiota, particularly those inhabiting the rhizosphere, contribute substantially to plant health through pathogen suppression, stimulation of plant defence responses, and enhanced nutrient acquisition.

The aim of this workshop is to open up the discussion of textual communities in Late Antiquity and the early Middle Ages, by offering a platform for PhD students from all over the world and from various disciplines to present their own research and discuss it with others. Deadline: April 23.

Promotor: F.J. van Lunteren, E. Jorin

Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven

The zoo of detected exoplanets reveals both the uniqueness of our own Solar System and the complexity of planetary system formation, sparking fundamental questions about how planetary systems form and evolve.

One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot

Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

Hydrocarbonylation of alkenes with carboxylic acids in synthesis of carboxylic acid anhydrides is relatively less explored. We herein present a study and optimization of a palladium-catalyzed hydrocarbonylation reaction of alkenes using carboxylic acids as the nucleophile, by which acid anhydrides can…

The applications of studying the early development of insects range from agriculture to material science.

Supramolecular polymers are class of materials that are formed by non-covalent interactions such as hydrogen bonding, π-π interactions, electrostatic interactions and the hydrophobic effect.

Cardiovascular disease is the leading cause of death worldwide.

Promotor: Prof.dr. R.M.H. Merks

My PhD thesis investigates the ecological significance of resistance against drought-induced air bubble formation inside the water conduits of plants (embolism), and the plasticity and functional aspects of stem anatomical traits in woody and herbaceous species.

A key step in the synthesis of oligosaccharides and glycoconjugates is the formation of the glycosidic bond.

Promotie

In this thesis we use state-of-the-art observations and simulations to provide the best constraints to date on the HVS ejection rate and constraints on the stellar content and dynamics at the GC, including the progenitor binary populations and their star formation history.

Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

Hydrogen peroxide (H2O2) is an important bulk chemical that is used in various industrial processes. More than 95% of the H2O2 used in industry is made via the anthraquinone process during which a large amount of energy is going to waste.

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Indigenous Latin American artifacts have attracted the interest of Europeans since the earliest moment of contact between Europeans and the Indigenous peoples of the Americas. The ERC-funded BECACO project uses an innovative multidisciplinary framework to investigate the provenance of ethnographic and…

Samuel Jong behaalt de masterscriptieprijs 2016 van het Instituut Politieke Wetenschap. Met ‘Bridging the Gap: Do Ideological Differences Determine Whether Center-Right Parties Cooperate with the Radical Right?’, rondde Jong zijn master Political Science af. Zijn bevindingen, zijn naar het oordeel van…

Een kijkje nemen in de atmosfeer van planeten ver buiten ons eigen zonnestelsel: de James Webb Space Telescope maakt het mogelijk. Leidse astronomen Yamila Miguel en Ignas Snellen leggen in de Volkskrant uit waarom de resultaten die binnenkort in Nature verschijnen zo spannend zijn.

Sterrenkundigen Ignas Snellen en Anthony Brown stonden met hun recentste ontdekking in De Telegraaf van 22 augustus. Ze wisten de massa van de pasgeboren exoplaneet Beta Pictoris b te bepalen. Hun ontdekking, die een publicatie opleverde in het blad Nature Astronomy, was zelfs het 'Nieuws van de dag…

Uit welke moleculen bouwen planeten zich op? Promovendus Christian Eistrup en zijn collega's hebben nieuwe modellen ontwikkeld om deze vraag te onderzoeken. Hun bevindingen zouden ons idee kunnen veranderen over welke moleculen Jupiter of zelfs de aarde vormden.

Ewine van Dishoeck doet onderzoek naar water in de ruimte. Ze is gespecialiseerd in scheikunde tussen de sterren, zoals ze astrochemie zelf noemt. Onlangs publiceerde ze een groot overzichtsartikel van haar werk. ‘Ik voel het als een plicht voor de volgende generatie om dingen op een rijtje te zette…

NASA’s telescoop SOFIA geeft een nieuw kijkje in de chemie nabij jonge sterren: de geboorteplaats van nieuwe planeten. De Leidse promovendus Andrew Barr schrijft erover in de Astrophysical Journal. Hij en zijn collega’s vonden enorme hoeveelheden water en organische moleculen in de wervelende, schijfvormige…