De Tweede Kamer, het kloppend hart van de Nederlandse democratie, bestaat tweehonderd jaar. Zestien gezaghebbende auteurs, waaronder Henk te Velde, Joris Oddens en Diederik Smit, schetsen in dit mooi uitgevoerde jubileumboek op toegankelijke wijze de ontwikkeling van deze volksvertegenwoordiging vanaf…

Kijk hier de colleges terug die hoogleraar Design Timo de Rijk gaf in de week van 5 t/m 9 oktober bij de Universiteit van Nederland. In de colleges van De Rijk vind je antwoorden op vragen als: 'Hoe werd de Nederlandse huisvrouw bevrijd?' en 'Hoe stalen wij de fiets van de Britten?' Een must see!

Developing new medicines is one of modern science's most significant hurdles, a process marked by high costs, long timelines, and frequent failures of promising candidates.

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

Inclusievere beoordelingsmethoden

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.

Volg een keuzevak in beeldende kunst, design of muziek!

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

SHINE-VR is een korte interventie in Virtual Reality (VR) die wordt toegevoegd aan een reguliere traumabehandeling (TF-CBT). We onderzoeken de effectiviteit ervan met een experimenteel ontwerp waarbij naar individuele gevallen wordt gekeken. Dit doen we specifiek met jongvolwassenen die seksueel misbruik…

Digitale editie van de correspondentie tussen de filosoof Gerardus Johannes Petrus Josephus (Gerard) Bolland (1854-1922) en de filoloog Pieter Jacob Cosijn (1840-1899), bestaande uit 46 brieven over de periode 1879 tot 1899.

Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman

Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

This thesis advance our understanding and the application of molecular catalysts relevant to the reduction of oxygen as well as reduction of nitrite.

Twee Leidse docenten hebben een Comenius-onderwijsbeurs van 100.000 euro gekregen waarmee ze een innovatie of verbetering in hun opleiding kunnen realiseren. De laureaten zijn Suzanne Mol, pedagogiek, en Lettie Dorst, taalkunde.

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

De Academy of Creative and Performing Arts biedt in samenwerking met een aantal instellingen voor hoger onderwijs in de kunsten, twee PhD-programma’s aan: in de muziek (docARTES) en de beeldende kunst en vormgeving (PhDArts). Deze programma's zijn beide internationale doctoraatsprogramma's voor praktijkgericht…

Laat je op deze pagina inspireren door best practices van onderwijsvernieuwende voorbeelden die in ons onderwijs invulling geven aan de ambitie Internationalisering en diversiteit.

Students Practicing Citizen Journalism

Onderzoek naar het ontwikkelen van privacy-vriendelijke zorg-games voor kinderen.

What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.

M. Danhof, Co-promotores: J. Freijer, A. Yassen

The invention of neural networks marks a critical milestone in the pursuit of true artificial intelligence. Despite their impressive performance on various tasks, these networks face limitations in learning efficiently as they are often trained from scratch.

Promotor: Prof.dr. C.W.J. Beenakker

Supramolecular polymers are class of materials that are formed by non-covalent interactions such as hydrogen bonding, π-π interactions, electrostatic interactions and the hydrophobic effect.

Promotor: Prof.dr. E. Deprettere

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

Laat je op deze pagina inspireren door best practices van onderwijsvernieuwende voorbeelden die in ons onderwijs invulling geven aan de ambitie Flexibele leerroutes.

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Lezing

Metal-organic compounds hold great promise as photoactivated chemotherapy (PACT) agents, leveraging their unique geometric and electronic properties to achieve precise spatiotemporal control over drug activation.

Het kernteam van het PDC is verantwoordelijk voor onderzoek en ontwikkeling van de LMW-methode en voert het beheer van de LMW trajecten binnen de verschillende deelnemende instellingen.

De vier nationale wiskundeclusters DIAMANT, NDNS, GQT en STAR krijgen, met ingang van september, elk 1 miljoen euro van het gebiedsbestuur NWO Exacte Wetenschappen voor een periode van twee jaar.

De traditionele scheiding van leeuwen in een Afrikaanse en een Aziatische ondersoort is onterecht, zegt bioloog Laura Bertola. In Afrika leven twee ondersoorten. Promotie 18 maart.