1,117 zoekresultaten voor “academic ondernemerschap” in de Publieke website
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Interview met European Youth Award winnaar Matteo Consonni
Matteo Consonni, Bestuurskunde alumnus aan de Universtiteit Leiden, won in 2015 de European Youth Award (EYA). In dit interview met de EYA vertelt hij wat hij sindsdien heeft gedaan en bespreekt hij het ondernemerschap.
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Business & Human Rights
Duurzaamheid is een van de centrale aandachtspunten van de Universiteit Leiden en speelt een steeds grotere rol binnen het onderwijs en onderzoek van de Faculteit der Rechtsgeleerdheid. Binnen deze context levert de afdeling Sociaal Recht een belangrijke bijdrage aan het debat en onderzoek rondom Business…
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Instituut voor Fiscale en Economische vakken
Het Instituut voor Fiscale en Economische Vakken bundelt onderwijs en onderzoek op het snijvlak van rechtsgeleerdheid enerzijds en fiscaliteit, economie en bedrijfswetenschappen anderzijds.Onder het instituut vallen de afdelingen Belastingrecht, Economie en Bedrijfswetenschappen. Vanwege zijn interdisciplinaire…
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Leerstoelen
Op de afdeling Bedrijfswetenschappen zijn drie leerstoelen gevestigd. De leerstoelhouders geven samen leiding aan het Turnaround, Rescue & Insolvency Leiden Research Team (TRI Leiden) dat bestaat uit juridische en bedrijfswetenschappelijke onderzoekers van de Leiden Law School. TRI Leiden streeft…
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Over de specialisatie
Bij de bachelorspecialisatie Informatica & Economie in Leiden leer je programmeren, algoritmen ontwerpen en data analyseren, maar óók hoe dit in het bedrijfsleven tot uiting komt. Je leert over ondernemerschap, finance, en strategie, en hoe deze onderwerpen samenhangen met software engineering en technieken…
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Afrika-Studiecentrum Leiden
In Afrika wonen 1,5 miljard mensen. Over 30 jaar zijn dat er 2,5 miljard. De impact van het continent op de wereldeconomie, maar bijvoorbeeld ook op het milieu, zal daardoor enorm toenemen. Onderzoekers van het Afrika-Studiecentrum Leiden (ASCL) zijn zich er al decennia van bewust dat Afrika een cruciale…
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Over de opleiding
De vakken binnen de master Recht & Bedrijfskunde combineren juridische en bedrijfskundige kennis. Ook besteden we binnen de vakken veel aandacht aan vaardigheden die later in je carrière goed van pas komen. De master is dus interdisciplinair van aard.
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Impact
Met ons onderzoek en onderwijs dragen we bij aan een betere wereld. We mengen ons in het wetenschappelijke en publieke debat, en zoeken antwoorden voor economische en maatschappelijke vraagstukken. Zowel lokaal en regionaal als mondiaal.
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MIMETAS wint COMS Young Technology publieksprijs & runner-up juryprijs
Spin-off bedrijf MIMETAS van de Universiteit Leiden heeft de Young Technology publieksprijs en de runner - up juryprijs gewonnen tijdens COMS 2013, een internationale conferentie over commercialisering van micro- en nanosystemen. MIMETAS ontwikkelt organen-op-een-chip met minuscule kanalen die als bloedvaten…
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Onderzoeksomgeving
De keten die patiënten voorziet van nieuwe medicijnen, bestaat uit diverse complexe schakels: van fundamentele wetenschap naar klinische tests tot productie. Deze hele keten is aanwezig in Leiden. De Universiteit Leiden, het Leids Universitair Medisch Centrum (LUMC) en de bedrijven op het Leiden Bio…
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Het ontstekingsremmende effect van het PRG4-eiwit: reumatoïde artritis verlichten en voorkomen
Kan het eiwit PRG4 helpen om de symptomen van reumatoïde artritis te voorkomen of te verlichten?
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Metabolomics Faciliteit
We leveren fenotypische read- outs voor diagnose en patiënt stratificatie voor een behandeling op basis van innovatieve metabolomics, UPE en organ-on-a-chip technologie. Met een farmacologische én biologische aanpak bieden we inzicht in ziektemechanismen en vertalen dat voor de gepersonaliseerde gen…
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Master Track Public Administration: Economics and Governance
The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…
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Security Studies
Security is key to survival for any living organism: life is full of perils and threats, both physically, environmentally, and societally. Security challenges such as terrorism, natural disasters, and cybercrime rank among the most pressing issues of our time, affecting the security and safety of millions…
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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Dosing considerations for preterm neonates: from pharmacometrics to clinical practice
Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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Reverse engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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Mast cells in advanced atherosclerosis: from human plaque stability to new therapeutic targets
In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.
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Wetenschapsoriëntatie en aansluiting
De juiste student op de juiste plek
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Citizenship, Migration and Global Transformations
Europese burgers worden geconfronteerd met uitdagingen op het gebied van globalisering, migratie, technologische ontwikkelingen en klimaatverandering. Deze uitdagingen vergen het uiterste van onderlinge internationale en intergenerationele solidariteit, wat rechtstreeks betrekking heeft op de grondslagen…
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Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity
The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.
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Dyslipidemia at the crossroad of the skin barrier and the arterial wall
The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…
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From every angle: novel insights into CC chemokine receptor 2 pharmacology
The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Development of a healthy and diseased artery-on-a-chip
Cardiovascular diseases are a leading cause of death worldwide, and better models are urgently needed for disease progression studies and drug development.
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Supercritical carbon dioxide spray drying for the production of stable dried protein formulations
Promotor: W. Jiskoot, Co-promotor: H.A. Every
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Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Human skin equivalents for atopic dermatitis: investigating the role of filaggrin in the skin barrier
Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri
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Fostering Curiosity Through Video Games
This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.
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Characterization of age-associated immunity in atherosclerosis
Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…
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Tsolin Nalbantian
Tsolin Nalbantian wil studenten leren hun kennis te vertalen naar een breed publiek.
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The road to insurmountability: Novel avenues to better target CC Chemokine receptors
This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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Osteosarcoma: searching for new treatment options
Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
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Preclinical validation of putative targets in cardiovascular and metabolic disease
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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Getting personal: Advancing personalized oncology through computational analysis of membrane proteins
Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.