1,586 zoekresultaten voor “weitin systems” in de Publieke website
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: M. Danhof, Co-promotor: E.C.M. de Lange
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Het legaliteitsbeginsel en de doorwerking van Europees recht in het Nederlandse materiële strafrecht
Het recht van de Europese Unie beïnvloedt direct en indirect de reikwijdte van strafrechtelijke aansprakelijkheid in Nederland. Die beïnvloeding heeft betekenis voor het materieelrechtelijk legaliteitsbeginsel.
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Soil and crop management options to improve nitrogen cycling on dairy farms on peat soil
The main research question of this thesis was: Can nitrogen cycling on dairy farms on peat soil in the Dutch Green Heart area be improved by adapting management to the nitrogen supply from soil and by using other grassland species and crops without affecting milk production?
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Don't Blink: Detecting transiting exoplanets with MASCARA
This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.
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Piecewise deterministic Markov processes: an analytic approach
Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans
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Activity-Based Proteasome Profiling
Promotor: Prof.dr. H.S. Overkleeft
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Dusty perspectives on the cradles of planets
De astronomie begon met het bestuderen van het licht van de sterren. Deze sterren worden geboren in uitgestrekte wolken van gas en stof.
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Oliver TaherzadehFaculteit der Wiskunde en Natuurwetenschappen
o.a.taherzadeh@cml.leidenuniv.nl | 071 5272727
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Hai LinFaculteit der Wiskunde en Natuurwetenschappen
h.x.lin@cml.leidenuniv.nl | 071 5277460
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Laboratoria Digital Archaeology
De onderzoeksgroep Digital Archaeology beheert twee computerlaboratoria voor verschillende doeleinden: een onderwijslab en een onderzoekslab.
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Solving the Gravitational N-body Problem with Machine Learning
In this work, I explore the creation of new methods that optimize simulations of the gravitational N-body problem. Specifically, I take advantage of the recent popularity of Machine Learning methods to find tools that can suit this problem.
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Geometry of Vegetation Pattern
One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.
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Estimation and Optimization of the Performance of Polyhedral Process Networks
Promotor: Prof.dr.ir. E. Deprettere
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Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
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Matching, entropy, holes and expansions
In this dissertation, matching, entropy, holes and expansions come together. The first chapter is an introduction to ergodic theory and dynamical systems.
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Md Faysal TareqFaculteit der Wiskunde en Natuurwetenschappen
m.f.tareq@cml.leidenuniv.nl | 071 5272727
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Bartolomeus Häussling LöwgrenFaculteit der Wiskunde en Natuurwetenschappen
b.j.p.m.haussling.lowgren@cml.leidenuniv.nl | 071 5272727
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Patterns on Spatially Structured Domains
We consider the propagation of electrical signals through nerve fibres.
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Willem MeilinkFaculteit der Wiskunde en Natuurwetenschappen
w.r.m.meilink@biology.leidenuniv.nl | 071 5274882
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A recipe for desert: analysis of an extended Klausmeier model
Promotores: Arjen Doelman, Jens Rademacher, Max Rietkerk
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Learning in Automated Negotiation
This dissertation advances automated negotiation by developing agents that can learn and adapt across diverse negotiation settings through three increasingly sophisticated approaches: automated algorithm configuration, portfolio-based strategy selection, and end-to-end reinforcement learning with graph…
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Geometry and arithmetic of del Pezzo surfaces of degree 1
This thesis contains results on the arithmetic and geometry of del Pezzo surfaces of degree 1.In Chapter 1 we give the necessary background, assuming the reader is familiar with algebraic geometry.
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Zsofia PilzFaculteit der Sociale Wetenschappen
z.p.pilz@fsw.leidenuniv.nl | 071 5272727
- From basic research to therapy development for neuromuscular disorders
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Hoe verschillende consumentengroepen wereldwijd een ongelijke impact hebben op milieu en gezondheid
Welke consumentengroepen hebben de grootste impact op de volksgezondheid en de planeet door hun voedingskeuzes, en hoe kunnen we deze inzichten gebruiken om de transitie naar duurzame eetpatronen te versnellen?
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Topology and Geometry in Chiral Liquids
We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Generalized Strictly Periodic Scheduling Analysis, Resource Optimization, and Implementation of Adaptive Streaming Applications
This thesis focuses on addressing four research problems in designing embedded streaming systems.
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Alexis de ColnetFaculteit der Wiskunde en Natuurwetenschappen
a.e.h.de.colnet@liacs.leidenuniv.nl | 071 5272727
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Ben WielstraFaculteit der Wiskunde en Natuurwetenschappen
b.m.wielstra@biology.leidenuniv.nl | 071 5275135
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Exploring Open-World Visual Understanding with Deep Learning
We are living in an information era where the amount of image and video data increases exponentially.
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Signatures of Majorana zero-modes in nanowires, quantum spin Hall edges, and quantum dots
Promotor: Prof.dr. C.W.J. Beenakker
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Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
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Microglial lipid metabolism: a delicate balance
Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
- Moons Beyond the Solar System
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The impacts and challenges of water use of electric power production in China
This thesis examines the impacts and challenges of water use of electric power system. This thesis found that there are large differences in water use of electricity technologies, with hydropower and thermal power being two large water users.
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CRISPR Cas-induced targeted mutagenesis with Agrobacterium mediated protein delivery
The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.
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Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
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Trading Responsibility: navigating national burdens in a globalized world
International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.
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Molecular sensors for calcium ion detection via triplet-triplet annihilation upconversion
Cardiovascular diseases (CVDs) are the leading global cause of mortality. Endothelial dysfunction, an early reversible stage of CVD development, is marked by decreased nitric oxide production linked to Ca2+ influx in endothelial cells.
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Bakti and Sayan traditions among the Tenggerese people in East Java: the role of indigenous institutions in integrated elderly care development
This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…
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Ubar Kampung
The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…
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Schijnconstructies en intra EU arbeidsmigranten (werkzaam in Nederland)
Het seminar op 30 november jl. over schijnconstructies en intra EU arbeidsmigranten trok veel belangstellenden en was een succes. Deze bijeenkomst werd georganiseerd vanuit het onderzoeksproject Solidarity under Strain (SOLID), onderdeel van de Research Focus Area 'Interaction between Legal Systems…
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Calculated Moves: Generating Air Combat Behaviour
By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.
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When materials become critical: lessons from the 2010 rare earth crisis
Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn