In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

Universiteit Leiden is op 28 september met twee projecten aanwezig bij het Discovery Festival, een nachtfestival dat draait om de kick die je krijgt als je nieuwe dingen ontdekt. Antibiotica Gezocht! laat de festivalgangers meewerken in het tijdelijke laboratorium en iSPEX: ‘Meet fijnstof met je smartphone’…

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

On 8 July, the symposium 'The digital reconstruction of the crucifixion of the Lindau master (ca. 1425)' will take place at the auditorium of Museum Catharijnecovent, from where it will also be broadcasted online.

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Promotie

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Sinds de 16e eeuw hebben religieuze overwegingen de studie van het Oudengels en zijn sprekers gemotiveerd. In de 19e eeuw wendden geleerden zich vooral tot de studie van de Oudengelse literatuur om sporen te vinden van voorchristelijke, 'Germaanse' religie, zoals besproken in Eric G. Stanley's baanbrekende…

Met ingang van 1 april 2018 is Erik Danen benoemd tot hoogleraar Cancer drug target discovery bij het Leiden Academic Centre for Drug Research (LACDR). Zijn vakgebied is celbiologie van kanker, waarin hij zich richt op de achterliggende mechanismen bij uitzaaiingen en resistentie voor behandelingen.

Promotor: Prof.dr. M. Ubbink, Co-promotor: G. Siegal

The Summer School History of the Book, organized by the Allard Pierson Museum, introduces a new course in English: Introduction to the Archaeology of the Book, taught by Prof. Malcolm Walsby (2-6 September 2024).

The first congress of the UU Paleohub, 'The Future of Paleography, Paleography of the Future'. 10 april 2025

Promotor: A. Achúcarro Co-promotor: A. Boyarsky

Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Op deze pagina vindt u de opnames van de online This Week's Discoveries vanaf 12 mei 2020 en een lijst sprekers vanaf oktober 2015.

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

This PhD research sets out to unravel and explain the socio-structural and cultural impacts of oil-industrialization on the local Bakhtiari community in general and the industrial laborers it provided in specific.

Congres/symposium

Van 21 augustus tot en met 8 september zijn de workshops en cursus van de jaarlijkse Summer School on the History of the Book van het Allard Pierson en de vakgroep Boekwetenschap. Drie weken lang is er elke werkdag een cursus, workshop of lezing over thema’s die te maken hebben met de geschiedenis van…

De Race of the Classics is het grootste studentenzeilevenement van Europa. Dit jaar werd de race van 4 t/m 10 april gevaren, met achttien schepen. Daan Kok, tweedejaars Fiscaal recht voer mee in team Leiden op de Tecla, een logger uit 2015. En legt uit hoe het Reesgevoel ontstaat.

Scott Waitukaitus is namens LION genomineerd als Discoverer of the Year 2017. Breng snel je stem uit!

Op vrijdagavond 17 september is de Leidse astronoom Joe Callingham te zien in een nieuwe serie op Discovery. ‘Killers of The Cosmos’ gaat over krachten in het heelal die ons bestaan kunnen bedreigen. Asteroïden, kosmisch puin, elektromagnetische wapens… De show behandelt elke bedreiging als potentiële…

Suzan Verberne is nominated by the Leiden Institute of Advanced Computer Science (LIACS) to be granted the C.J. Kok Public Award, also known as the award for the ‘Discoverer of the Year’.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

Op deze pagina vind je de opnames van de Tuesday Talks sinds april 2025. Ook de opnames van de voorloper van de Tuesday Talks, This Week’s Discoveries, zijn hier te vinden

The 7th European Congress of Medieval Studies of the Fédération Internationale des Instituts d’Études Médiévales (FIDEM) will be organized by the Department of Arts, Media, and Philosophy of the University of Basel, Switzerland. There is a number of slots for papers (20 minutes) and special sessions…

Stem voor de Ontdekker van het jaar 2017! Wie van deze onderzoekers verdient volgens jou een prijs voor zijn of haar werk? Vanaf nu kan je stemmen!

Call for poster presentations: Future of Paleography, Paleography of the Future. 10 April 2025, Utrecht.

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Op 27 juni 2019 verdedigde Barry Bussey zijn proefschrift 'The Legal Revolution Against the Accommodation of Religion: The Secular Age v. The Sexular Age'. Het promotieonderzoek is begeleid door promotor prof. dr. P.B. Cliteur.

Het boek 'The United Nations Convention on the Rights of the Child' is het resultaat van internationale wetenschappelijke congres - '25 Years CRC' – dat plaatsvond in november 2014 in Leiden ter gelegenheid van de 25e verjaardag van het VN-Kinderrechtenverdrag.

State of the Art Crisisbeheersing 2