3,087 zoekresultaten voor “discovery of the year” in de Publieke website
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Hunting dark matter with X-rays
Promotor: A. Achúcarro Co-promotor: A. Boyarsky
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Non-invasive biomarkers for inflammatory skin diseases: towards systems dermatology
Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Chemical tools to modulate endocannabinoid biosynthesis
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Race Of The Classics: het Reesgevoel forever
De Race of the Classics is het grootste studentenzeilevenement van Europa. Dit jaar werd de race van 4 t/m 10 april gevaren, met achttien schepen. Daan Kok, tweedejaars Fiscaal recht voer mee in team Leiden op de Tecla, een logger uit 2015. En legt uit hoe het Reesgevoel ontstaat.
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Some Assembly Required: The Structural Evolution and Mass Assembly of Galaxies at z
This thesis investigates the structural evolution and assembly of galaxies since the first few billions years after the big bang.
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Waarom Universiteit Leiden?
De masteropleiding International Organisation wordt aangeboden door de Universiteit Leiden in Den Haag. Op deze pagina wordt uitgelegd waarom studenten voor deze opleiding en locatie kiezen.
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Astronoom Joe Callingham getuigt tegen killer-sterren in nieuwe show op Discovery
Op vrijdagavond 17 september is de Leidse astronoom Joe Callingham te zien in een nieuwe serie op Discovery. ‘Killers of The Cosmos’ gaat over krachten in het heelal die ons bestaan kunnen bedreigen. Asteroïden, kosmisch puin, elektromagnetische wapens… De show behandelt elke bedreiging als potentiële…
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Picturing Scholasticide: The Future of Higher Education in Palestine
Hoe beïnvloedt de vernietiging van universiteiten in Gaza, ook wel 'scholasticide' genoemd, het wetenschappelijk leven en wat zijn de theoretische en juridische onderbouwingen van de term?
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CfP 2023 FIDEM Congress: The Medieval Book Through the Lens of the Librarian (Basel)
The 7th European Congress of Medieval Studies of the Fédération Internationale des Instituts d’Études Médiévales (FIDEM) will be organized by the Department of Arts, Media, and Philosophy of the University of Basel, Switzerland. There is a number of slots for papers (20 minutes) and special sessions…
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Poster presentations: Future of Paleography, Paleography of the Future
Call for poster presentations: Future of Paleography, Paleography of the Future. 10 April 2025, Utrecht.
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Marina Gorostiola GonzálezWiskunde en Natuurwetenschappen
m.gorostiola.gonzalez@lacdr.leidenuniv.nl | 071 5272727
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CfP: 25 Years after Hillenbrand (Groningen, 10-12 October)
On 10-12 October 2024, a workshop is held at the University of Groningen, titled: "25 years after Hillenbrand: New Approaches to Sources, Translation and Perspectives". The organisers aim to gather specialists and early career researchers in the field of crusader studies to discuss emerging research…
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Winds in the AGN environment: new perspectives from high-resolution X-ray spectroscopy
Promotor: J.S. Kaastra Co-promotor: E. Constantini
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Mind the gap: gas and dust in planet-forming disks
Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond
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When materials become critical: lessons from the 2010 rare earth crisis
Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn
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Jewish Life: Visualizing the Jewish Experience
Deze colleges zijn in het Engels, u kunt vragen stellen en reageren in het Nederlands.
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Eani LachmansinghWiskunde en Natuurwetenschappen
e.t.lachmansingh@liacs.leidenuniv.nl | 071 5272727
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The road to insurmountability: Novel avenues to better target CC Chemokine receptors
This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.
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Archief
Op deze pagina vindt u de opnames van de online This Week's Discoveries vanaf 12 mei 2020 en een lijst sprekers vanaf oktober 2015.
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Microglial lipid metabolism: a delicate balance
Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.
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Chemical tools to monitor and control proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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Anti-microbial and Anti-biofilm compounds From Indonesian Medicinal Plants
Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Archief
Op deze pagina vind je de opnames van de Tuesday Talks sinds april 2025. Ook de opnames van de voorloper van de Tuesday Talks, This Week’s Discoveries, zijn hier te vinden
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Infographic eindrapport State of the Art Crisisbeheersing 2
State of the Art Crisisbeheersing 2
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It's about time
This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.
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Why Minor Powers Risk Wars with Major Powers: A Comparative Study of the Post-Cold War Era
Aan de hand van een reeks case studies in Irak, Moldavië en Servië gedurende het post-Koude Oorlogstijdperk, onderzoekt dit boek asymmetrische conflicten waarbij de strijdende partijen een grote ongelijkheid in machtsposities vertonen.
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The first graduates of the Faculty of Governance and Global Affairs: LUC’s Class of 2015½!
LUC is the first to confer the diploma of the Faculty of Governance and Global Affairs, the new Faculty name since January 2016 making this graduation an extra special occasion.
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longitudinal analysis of different dimensions of the desistance process among long-term prisoners in the Netherlands
Op 5 september 2019 verdedigde Jennifer Doekhie haar proefschrift 'Dimensions of desistance: A qualitative longitudinal analysis of different dimensions of the desistance process among long-term prisoners in the Netherlands'. Het promotieonderzoek is begeleid door promotor prof.dr. P. Nieuwbeerta.
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Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration
Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.
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Uitnodiging Jaap Doek Kinderrechtenscriptieprijs 2016 & Boekpresentatie ‘25 years CRC’
De Afdeling Jeugdrecht en Defence for Children nodigen u van harte uit voor de uitreiking van de vierde Jaap Doek Kinderrechtenscriptieprijs en de officiële presentatie van het boek ‘The United Nations Convention on the Rights of the Child. Taking Stock after 25 Years and Looking Ahead’.
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China’s industrial carbon emissions: Historical drivers at the regional and sectoral levels and projections in light of policy
This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.
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North Sea noise in the Anthropocene: an impact study of human-made impulsive sounds on free-ranging cod
Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.
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Celebrating Twenty Years of MIRD
Op 25 maart vierde de Advanced Masters of Science in International Relations and Diplomacy (MIRD) zijn 20-jarige bestaan. Gedurende de dag werd de hechte community van MIRD alumni in het zonnetje gezet. De feestelijkheden gingen van start met het Reconnect event, voor huidige studenten en alumni, en…
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Ecoloog Michiel Veldhuis is de Ontdekker van het Jaar 2020
Michiel Veldhuis heeft bij de C.J. Kok Publieksprijs de meeste stemmen van het publiek gekregen en mag zich daarmee Ontdekker van het Jaar noemen. Veldhuis onderzoekt hoe klimaatverandering ecosystemen op de savannes in Afrika beïnvloedt en hoe we die ecosystemen kunnen beschermen.
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The origins of friction and the growth of graphene, investigated at the atomic scale
Promotor: J.W.M. Frenken
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Agenda dynamics in the European Union : the interaction between the European Council and the European Commission in the policy domain of organized
The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…
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PhD position: Staging Nobility in Urban Space. The Nassau Dynasty and the Towns of the Low Countries
The University of Amsterdam is looking for a PhD researcher in the NWO-funded project "Staging Nobility in Urban Space. The Nassau Dynasty and the Towns of the Low Countries (c. 1400-c. 1570)". This PhD project identifies the impact the Nassau dynasty had on urban space in the Low Countries and investigates…
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The impact of defense hormones on the interaction between plants and the soil microbial community
The soil ecosystem consists of the largest reservoir of biodiversity on Earth.
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Hunting for the fastest stars in the Milky Way
The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.
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Peeking into the future: Fungi in the greening Arctic
Promotor: E.F. Smets, Co-promotor: J. Geml