The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Het begrijpen van individuele verschillen in zelfregulatie bij jongens met ODD/CD op het niveau van het brein, cognitie en gedrag

In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.

Promotor: A. Kros

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.

Planets are formed in disks of gas and dust around young stars.

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Promotor: G.R. de Snoo, Co-promotor: C.J.M. Muster

Thirty years ago, mutations in the BRCA1 gene were first linked to hereditary breast and ovarian cancer, establishing a genetic basis for cancer development.

Promotor: Prof.dr. E.F. van Dishoeck

Promotor: J.W.M. Frenken

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Consequences for sediment stability and seston trapping

The applications of studying the early development of insects range from agriculture to material science.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Promotores: Prof.dr. G.A. van der Marel, M. van Heel

Promotor: Prof.dr. T. Schmidt

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: W. Jiskoot, Co-promotor: H.A. Every

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Promotor: Prof.dr. R.M.H. Merks

Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

The LOFAR radio telescope produces petabytes of data every year. Radio Astronomers use complex multi-step pipelines to process this data and produce scientific images.

Lezing

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

This dissertation investigates how the efficiency of Computed Tomography (CT) can be improved for dynamic scientific and industrial applications.

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

Deze master specialisatie behandelt een breed scala aan wetenschappelijke onderwerpen, waaronder High Energy Physics and Particle Cosmology, Theoretical Physics of Life Processes en Condensed Matter Theory.

In deze master specialisatie ligt de focus op het begrijpen van biologische processen in hun natuurlijke context, zoals cellen en weefsels.

De masterspecialisatie Global Order in Historical Perspective van de Universiteit Leiden, richt zich in het bijzonder op het bestuderen van de historische processen die ten grondslag liggen aan de evolutie van de wereldorde.

Hooggevoeligheid, of sensorische verwerkingsgevoeligheid, wordt steeds vaker besproken in de media, maar wat betekent het eigenlijk om hooggevoelig te zijn? In deze aflevering deelt Véronique de Gucht, universitair hoofddocent aan de Universiteit Leiden, haar expertise over dit onderwerp.

Het onderzoek van het Brain and Education Lab richt zich op de ontwikkeling van cognitieve processen die betrokken zijn bij leren en academische vaardigheden zoals begrijpend lezen, wiskunde en ruimtelijke vaardigheden. Daarbij richt het onderzoek zich specifiek op één van de meest opwindende fasen…

Deze tweejarige masteropleiding wordt aangeboden door het Leiden Institute of Chemistry en heeft een focus op technologische en fundamentele kennis en expertise. Tijdens de opleiding doe je onderzoek naar de processen van de levende cel met fundamenteel wetenschappelijke én toegepaste technologie. Je…