Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

In this project of the Center for Public Values & Ethics (CPVE) ongoing research is conducted on the history of advice to Dutch central government by so-called State committees from 1814 to 2014. State committees have been installed by Dutch central government since 1814 to provide expert advice, research…

Archeologe José Joordens reageert in het BNR radioprogramma Wetenschap Vandaag op de ontdekking dat onze oudste voorouders meer in bomen leefden dan gedacht.

Marcellus Ubbink, hoogleraar Eiwitchemie, heeft een ECHO-subsidie van NWO ter waarde van 260 duizend euro in de wacht gesleept. Met het geld gaat hij onderzoek doen naar enzymremmers.

Tijdens de ILS Lunch Seminars kunnen alle onderzoekers van de faculteit hun onderzoek presenteren. Het doel is om op een toegankelijke en efficiënte manier op de hoogte zijn van onderzoeken van verschillende onderzoeksprogramma's en instituten. Gedurende een seminar van een uur zullen twee of drie sprekers…

ILS organizes a new lunch seminar series where all researchers from Leiden Law School can present their research. The idea is to hear in a simple and nice way what researchers from other research programs and institutes are working on. During a seminar two or three speakers will present their research.…

Afgelopen weekend heeft Italië aan Nederland verzocht twee schepen terug te roepen die onder de Nederlandse vlag varen voor de Libische kust.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

In dit interdisciplinaire onderzoeksprogramma werken onderzoekers uit vijf verschillende disciplines met elkaar samen. Zij stellen zich hieronder (in het Engels) aan u voor.

Promotor: G.P. van Wezel

The role of the interfacial environment during electrochemical reactions has been increasingly valued, especially for those reactions involving protons or hydroxyl ions.

This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Op vrijdag 24 maart aanstaande zal Prof. Amanda Perry–Kessaris (Kent Law School) de maandelijkse Leiden Socio-Legal Lecture verzorgen.

‘Wat ik aantrekkelijk vind aan het bodemleven, is dat het stuurbaar is,’ verklapt onderzoeker Martijn Bezemer van het Instituut Biologie Leiden (IBL). ‘Dat je kan zeggen: wat wil je? En dat ik de bodem dan kan omtoveren tot iets wat jij nodig hebt. Ten minste, dat dachten we.’

In this course, you will learn about sustainability and staying with the environmental boundaries of our planet. You will gain an understanding of the effects of growing affluence and population growth, the key challenges we are facing, and ways to influence your direct environment.

Urbanisation is steadily increasing with estimates expecting that 68% of the global population will live in cities by 2050. To accommodate the rural to urban transition, large quantities of land are transformed from natural to urban lands.

In het NOS journaal op Radio 1 van dinsdag 6 februari spreekt Wil Roebroeks over de ontdekking van 171.000 jaar oude graafstokken. Het bestaan van dit gereedschap werd al langer vermoed, maar er waren nog niet eerder exemplaren van gevonden.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Lipid formulations have demonstrated strong potential for nucleic acid delivery,particularly with the success of COVID-19 vaccines. Despite these advances, manyaspects of lipid formulations remain unclear.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L. Kaper (UvA)

Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.

Promotor: Prof.dr. D. Bouwmeester

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

This thesis systematically analyzes the physical-chemistry of lipid-graphene interactions with the major objective of reconciliating the variety of results reported in the literature.

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.

This thesis describes how to scale down concepts of macroscopic mechanical metamaterials to the thermal scale using a system of flexibly-linked colloids.

The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.

Promotor: F. Arbab

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

Promotie

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.