Mechanical interactions between cells and their environment play an important role in many biological processes.

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

Archeologe José Joordens reageert in het BNR radioprogramma Wetenschap Vandaag op de ontdekking dat onze oudste voorouders meer in bomen leefden dan gedacht.

Sinds de oprichting is LUC een college voor onderwijsontwikkeling en experimentatie. In de missie van het college wordt LUC beschreven als "een plek van innovatie op het gebied van didactiek, curriculumontwerp en studentwelzijn." Deze visie wordt toegepast via een studentgerichte benadering in het onderwijs…

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

Marcellus Ubbink, hoogleraar Eiwitchemie, heeft een ECHO-subsidie van NWO ter waarde van 260 duizend euro in de wacht gesleept. Met het geld gaat hij onderzoek doen naar enzymremmers.

Tijdens de ILS Lunch Seminars kunnen alle onderzoekers van de faculteit hun onderzoek presenteren. Het doel is om op een toegankelijke en efficiënte manier op de hoogte zijn van onderzoeken van verschillende onderzoeksprogramma's en instituten. Gedurende een seminar van een uur zullen twee of drie sprekers…

ILS organizes a new lunch seminar series where all researchers from Leiden Law School can present their research. The idea is to hear in a simple and nice way what researchers from other research programs and institutes are working on. During a seminar two or three speakers will present their research.…

Afgelopen weekend heeft Italië aan Nederland verzocht twee schepen terug te roepen die onder de Nederlandse vlag varen voor de Libische kust.

This research project studies the distribution and impact of medieval malaria in the Netherlands.

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Promotor: G.R. de Snoo, Co-promotores: M.G. Vijver, J.P.M. Vink

Het wemelt van de voetafdrukken die de druk van de mens op het milieu berekenen. Milieukundige Kai Fang is de eerste die een voetafdrukfamilie ontwikkelde waardoor milieuschade en uitputting van hulpbronnen beter gemeten kan worden. Promotie 24 november.

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The findings in this thesis improve the understanding of 1) the relationship between exposure characteristics and toxicity of ENPs, 2) the joint toxic action of ENP mixtures and the comparison to metal salt mixtures, 3) how NOM affects the individual and joint toxicity of ENPs, 4) the extent of trophic…

The global agri-food system plays a critical role in food security and environmental issues.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Op vrijdag 24 maart aanstaande zal Prof. Amanda Perry–Kessaris (Kent Law School) de maandelijkse Leiden Socio-Legal Lecture verzorgen.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

Promotores: Prof. dr. G.R. (Geert) de Snoo, Dr. E. (Ester) van der Voet

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Lipid formulations have demonstrated strong potential for nucleic acid delivery,particularly with the success of COVID-19 vaccines. Despite these advances, manyaspects of lipid formulations remain unclear.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.