De theoretische wereld van wiskunde en informatica naar meer toegepaste onderzoeksgebieden brengen. Dat is wat Daan Pelt, universitair docent bij het Leiden Institute of Advanced Computer Science (LIACS) probeert te bereiken met de methodes die hij ontwikkelt als oplossing voor uitdagingen in beeldv…

Het Data Science Onderzoeksprogramma (DSO) combineert Leidse promotieonderzoeken uit allerlei disciplines met data science. Het programma loopt nu ruim twee jaar, en levert verrassende eerste resultaten op. Hieronder vertellen een aantal promovendi over hun ervaringen en hun onderzoek.

In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.

Explore "Statistical Aspects of Clinical Trials" at Boerhaave Nascholing. Dive into trial design, analysis, and practical sessions. Read more here.

Explore "Statistical Aspects of Clinical Trials" at Boerhaave Nascholing. Dive into trial design, analysis, and practical sessions. Read more here.

The project

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

Hoe kan een CLIL-aanpak, met een focus op Disciplinary Literacies, het literatuuronderwijs van het LLA-programma in de bovenbouw van het tweetalig onderwijs (TTO) verbeteren?

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Kunst en vrije tijd, Kunst en vrije tijd

Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov

Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.

The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

Het merendeel van de wetenschappers, van archeologen tot zoölogen, verzamelt enorme hoeveelheden gegevens. Hun databanken bevatten grote hoeveelheden informatie die voor de mens moeilijk te filteren zijn. Met een stevige basis in de statistiek en de computerwetenschappen kunnen we algoritmes ontwikkelen…

Veel Nederlandse schaatsers en voetballers behoren tot de absolute wereldtop. Toch kunnen ze dankzij slimme statistische analyses wellicht nóg een beetje beter worden. De Universiteit Leiden werkt er samen met Delft en Amsterdam aan.

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

Woensdag 14 juli publiceerden Nederlandse astronomen een primeur in vakblad Nature. Het was hen als eersten ter wereld gelukt om isotopen te ontwaren in de damkring van een exoplaneet. Een ontdekking die ons meer kan leren over het ontstaan van planeten. Verschillende media schreven over de bijzondere…

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.

Data theory research on the analysis on the multidimensional data

In the era of big data, extracting insights from complex datasets is a key challenge. This thesis demonstrates the superiority of graph-based methods over traditional clustering (e.g., k-means, DBSCAN) and outlier detection for analyzing high-dimensional and noisy data.

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.