The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.

Sociale Wetenschappen, Politieke Wetenschap

This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…

Some examples of research questions include: What framework of circular strategies should local practitioners use? How should practitioners organize their monitoring of the circular economy activities in the region of interest? What are the main products that have the most circular potential in the…

Congres/symposium

Arco Timmermans, bijzonder Hoogleraar Public Affairs aan het Instituut Bestuurskunde van de Universiteit Leiden, werd door Radio EenVandaag uitgenodigd om samen met Mark van Baal van Follow This te spreken over de invloed die een miljardenbedrijf als Shell op de buitenwereld heeft.

This course uses the lives, ideals and achievements of Theodore, Franklin, and Eleanor Roosevelt to create the idea of a Rooseveltian century. It is an invitation to think critically and historically, and it wants to give you a glimpse of what it means to be a historian at work.

This course provides an insider perspective into the work of international criminal courts and tribunals. You will learn about the investigation and prosecution of international crimes in The Hague.

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

EXIOBASE is a global, detailed Multi-regional Environmentally Extended Supply and Use / Input Output (MR EE SUT/IOT) database. It was developed by harmonizing and detailing SUT for a large number of countries, estimating emissions and resource extractions by industry, linking the country EE SUT via…

Promotor: E. Gittenberger, Co-promotores: B.W. Hoeksema; L.P. van Ofwegen

The findings in this thesis improve the understanding of 1) the relationship between exposure characteristics and toxicity of ENPs, 2) the joint toxic action of ENP mixtures and the comparison to metal salt mixtures, 3) how NOM affects the individual and joint toxicity of ENPs, 4) the extent of trophic…

In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).

Promotor: J.M. Memelink

Binnen het brede netwerk van de Universiteit Leiden neemt het instituut deel aan onderzoek binnen de volgende profileringsgebieden:

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

Als Europese landen alleen vertrouwen op technologische vooruitgang, kunnen we de opwarming van de aarde niet beperken tot 1,5 graad. Ook huishoudens moeten hun levensstijl veranderen. Deze 'inconvenient truth' is het resultaat van de berekeningen van industrieel ecoloog Stephanie Cap. ‘Het is geen…

The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…

Res Publica een Nederlandstalige wetenschappelijk tijdschrift voor politieke wetenschap, bestuurskunde, Europese en internationale politiek, politieke sociologie en communicatiewetenschap.

Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

A brief review essay on some of the work that has been recently published in the emergent field of digital ethnography.

De komende twee jaar gaat het Van Vollenhoven Instituut (VVI) in samenwerking met ICEL, the Indonesian Center for Environmental Law in Jakarta, op verschillende fronten werken aan verbeterde milieuhandhaving in Indonesië.

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.

The mission of our group is understanding how science communication works to improve the interaction between science and society. We believe better science communication can improve our society and engage many different groups with science, also improving science.

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

Promotor: Peter Stevenhagen

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.

PhDArts co-director Dr. Janneke Wesseling’s e-book ‘De volmaakte beschouwer, De ervaring van het kunstwerk en receptie-esthetica’ was recently published. The key question of the book is: how does the work of art work?

Machine Learning is becoming a more and more substantial technology for industry.

This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…

The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).

The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.

In this work, we illustrate unconventional approaches towards the fabrication of edge functionalized graphene nanostructures and bidimensional architectures in polymeric and metallic supports, with an outlook towards molecular sensing devices.

Possible improvements for the assessment of abiotic depletion in LCA.

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

Promotie

Na een omweg via de ANWB in München werkt alumna Manon Schouten op twee scholen als docent geschiedenis. 'Het is mooi meegenomen dat ik nu veel van auto’s weet, maar dat weegt niet op tegen het gevoel dat ik krijg als ik de lesstof echt zie landen bij leerlingen.’

‘We moeten op zoek naar producten die gewone wegwerpplastics kunnen vervangen, bijvoorbeeld van plantmateriaal. Binnen een jaar of 20 is het gemiddelde plasticgebruik van een huishouden met grote slagen verminderd.’ Volgens Thijs Bosker, Universitair Hoofddocent aan het Leiden University College, in…