In this thesis, we examine various systems through the lens of several numerical methods.

Cursus

Promotores: F.H.J. Redig, W.T.F. den Hollander

The global agri-food system plays a critical role in food security and environmental issues.

Promotores: G.A. Persoon, H.H. de Iongh

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Op vrijdag 24 maart gaf prof: Amanda Perry-Kessaris (Kent Law School) een korte workshop over data visualisation voor de promovendi van de afdeling Economie. Tijdens deze workshop werden de promovendi uitgedaagd om door middel van LEGO hun onderzoek te visualiseren. Amanda Perry-Kessaris gaf daarna…

In het kader van ILS 2.0 zijn er restgelden beschikbaar voor het indienen van subsidievoorstellen en - direct daaraan gekoppeld en inherent daaraan - het ontwikkelen van nieuwe onderzoekslijnen. Per aanvraag geldt een maximumbudget van 40.000 euro. In totaal is 180.000 euro beschikbaar voor deze cal…

Op vrijdag 24 februari zal Prof. Judith Masson (Bristol University), Hoogleraar Rechtssociologie en Fellow bij the UK Academy of Social Science, een lezing geven binnen de Leiden Socio-Legal Series.

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

In this thesis, classes of strongly interacting quantum field theories, have been studied.

This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Promotor: Prof.dr. S. Haring

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

This thesis describes how to scale down concepts of macroscopic mechanical metamaterials to the thermal scale using a system of flexibly-linked colloids.

Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.

Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Promotor: R.D. Gill, F. Taroni

Promotor: B. van de Water

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

With the advent of multicore processors and data centers, computer hardware has become increasingly parallel, allowing one to run multiple pieces of software at the same time on different machines. Coordination of these pieces is best expressed in a coordination language as an explicit interaction protocol…

To study how planetary systems come into existence we study much younger systems still in formation.

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

Inspired by natural photosynthesis, perovskite-based photoelectrochemical (PEC) systems are being developed for artificial photosynthesis, aiming to enhance solar-to-hydrogen conversion for green energy.

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Understanding interactions in quantum many-body systems remains one of the most profound and difficult challenges in condensed matter physics.

Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…

Biodiversity enables ecosystems to thrive through the synergy of functional differences among organisms. While human well-being strongly depends on biodiversity-driven ecosystem services, human actions are also at the root of current unprecedented biodiversity declines.

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

Denk je schaamte om en maak het je kracht.

This thesis advances automata learning, a key area in computer science, with applications in software verification, biological analysis, and autonomous technologies. It explores three main themes: first, it introduces a passive learning algorithm for generating compact probabilistic models from positive…

De samenwerkingsbereidheid van leerlingen ligt ten grondslag aan een goede relatie tussen leraar en leerling, en is positief gerelateerd aan de betrokkenheid met school van leerlingen. Het bevorderen van samenwerkingsbereidheid in plaats van tegendraads gedrag van leerlingen zou vooral nuttig kunnen…

The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.

The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Promotor: Prof.dr. H.L.V. Linnartz

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

The use of increasingly large and diverse datasets to guide urban climate action has implications for how, and by whom, local governments are held accountable.