Insecteneieren zijn niet zo weerloos als werd gedacht. Ze hebben een beschermlaag die hen behoedt voor invloeden van buitenaf. Dit ontdekte bioloog Chris Jacobs. De antibacteriële stoffen die in deze laag worden geproduceerd, zijn mogelijk goede antibiotica. Promotie 4 december.

In this dissertation (titled: Exploring the Synergies between Transfer in Reinforcement Learning and Procedural Content Generation) we explore how the two research fields named in the title, namely Transfer in Reinforcement Learning (TRL) and Procedural Content Generation (PCG) can synergize togethe…

Kunst en vrije tijd, Kunst en vrije tijd

Stephanie Rap and Chrisje Sandelowsky-Bosman hebben bijgedragen aan het produceren van een online instructiehandleiding voor advocaten, welke is ontwikkeld als onderdeel van het trainingsprogramma Advancing the Defence Rights of Children.

Promotores: R. Tijdeman, K.J. Batenburg

Risk has become one of the defining features of modern society. This course examines various types of safety and security risks, and how these are perceived and dealt with in a wide array of professional and academic fields, ranging from criminology, counter-terrorism and cyber security, to philosophy,…

Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

Lezing

In mei 2021 vond het TPR-colloquium plaats dat ging over de rol van het privaatrecht bij het verduurzamen van onze samenleving en was georganiseerd door Maastricht University, KU Leuven, Rijksuniversiteit Groningen en Stellenbosch University.

Promotor: Prof.dr. M.A.G.J. Orrit

Dynamical systems describe the evolution of objects in a space over time and may be used to model physical phenomena. Due to this, much research is dedicated to understanding the mathematics of dynamical systems.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

In the Schouwburgstraat, LUGO is currently redesigning the back-garden in order to increase biodiversity and make it a more beautiful space. Throughout October 2023 until March 2024, we will be making changes to the garden with our team of volunteers.

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

Promotor: Prof.dr. G.R. de Snoo

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

Aan het LUCL pogen onderzoekers om de taaldiversiteit van de inheemse bevolking van Amerika te begrijpen, te bestuderen en te behouden.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

The upscaling of Life Cycle Assessment (LCA) data is recognized as one of the main challenges in the ex-ante LCA of emerging technologies. This challenge arises since industrial-scale system specifications for these technologies are unknown and industrial data is lacking.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.

Lezing

Kiemproject: Hoe kunnen metaforen bijdragen aan betere maatschappelijke betrokkenheid bij quantumwetenschap en -technologie, en welke factoren beïnvloeden de acceptatie of weerstand tegen metaforen bij zowel experts als leken?

Onze deskundige coaches doen hun beste speechtips van de hand in deze korte video's. Leerlingen kunnen deze adviezen meteen inzetten in de Max Havelaar-lessenserie en docenten kunnen de tips gebruiken in hun eigen lessen over het gesproken woord.

Welke kansen en bedreigingen vloeien voort uit de institutionele en normatieve diversiteit op het terrein van de rechten van de mens voor de effectieve bescherming van die rechten in een wereld die gekenmerkt wordt door pluralisme?

Archeologie alumnus Chris Muysson won de W.A. van Es-prijs tijdens de Reuvensdagen van 2023. Hij ontving deze prijs voor zijn uitvoerige masterscriptie-onderzoek naar de geschiedenis van de visconsumptie in Nederland.

Door de coronacrisis is het een stuk lastiger geworden om in het buitenland te studeren of om daar onderzoek te doen. Geneeskundestudent Jacqueline Claus was de pandemie nog voor. Haar onderzoek in Boston naar dementie na een beroerte is nu genomineerd voor de Professor Chris Gips Studentenprijs.

De wereldwijde reacties op de gebeurtenissen in Charlottesville hebben veel losgemaakt, ook in Nederland. Leidse historici hebben in de afgelopen weken ook gereageerd.

Sinds 2009 behaalden 95 kandidaten hun doctoraat in Creative en Performing Arts. Op deze pagina een overzicht van ACPA's alumni.

LUMC’er Mark Smeets is genomineerd voor de Professor Chris Gips Studentenprijs. Dit is een prijs voor het beste wetenschappelijk onderzoek onder Nederlandse geneeskundestudenten. Smeets onderzocht in de Verenigde Staten hoe stamcellijnen reageren op verschillende vormen van medicatie.

The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

How did colonial law work to turn people into property? This project argues that colonial ideas about households and domestic authority were critical to legal processes of enslavement in the early modern Dutch empire. Using colonial court records from Dutch Brazil, Suriname, and the Moluccas, the project…

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

Studievoorlichting

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)