Promotie

Promotie

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Promotor: Prof.dr. H.L.V. Linnartz

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.

Can we develop a platform for raw materials intelligence?

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

Using the principles of Industrial Ecology in Environmental Policy making in two cases: transition to a hydrogen economy and chlorinated compounds.

To deliver a Virtual Sensor tool optimised to exploit the synergy between Sentinels 2 and 3 to allow the consistent retrieval of land surface parameters (Albedo, LAI, and LST); To extend the existing capabilities of land EO data assimilation tools to add capacity to handle data in the thermal domain…

What are the environmental trade-offs for SMEs considering moving from monoculture aquaculture practice towards IMTA? What are the environmental trade-offs comparing IMTA species with their conventional monoculture alternatives?

Behavioral and neural mechanisms underlying self-concept development in relation to educational decision-making in adolescence

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

Deze opleiding is gericht op de ontwikkeling van computermodellen die de werking van medicijnen voorspellen, het individualiseren van bestaande behandeltherapieën en het ontwikkelen van innovatieve, analytische tools voor het personaliseren van de gezondheidszorg.

Didactiek

Governance and Global Affairs, Leiden University College The Hague

Promotie

Promotie

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Promotor: Ronald Cramer, Co-promotor: Serge Fehr

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

​​​​​​​Op dit moment wordt er veel gesproken over diversiteit, gelijkwaardigheid en inclusiviteit, maar wat houdt dat eigenlijk in? Met passende tools weet jij een bijdrage te leveren aan een divers en inclusief beleid in jouw organisatie. Je bent je bewust van welke vraagstukken er spelen rondom Diversiteit…

Single-Molecule Microscopy (SMM) techniques constitute a group of powerful imaging tools that enable researchers to study the dynamic behavior of individual molecules.

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

Optical cavities are useful tools to enhance the interaction between light and matter, which is important to make good quantum emitters. However, it turns out that the cavities themselves (without any quantum emitters) are already interesting objects to study.

Promotie

Steden, Voedsel, Water, Biodiversiteit, Bronnen en Energie: dit zijn de belangrijkste onderzoeksthema’s voor het CML. Ons doel is altijd om wereldwijd voorop te lopen in ons vakgebied. En echte impact te hebben met onze onderzoeksprogramma’s.

Promotie

Lezing

Volg een Masteropleiding na het behalen van je Bachelor Pedagogische Wetenschappen.

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

het Instituut Pedagogische Wetenschappen verzorgt verschillende bacheloropleidingen, de academische Pabo, een pre-masterprogramma en de masteropleiding Education and Child Studies.

Het Leidse Instituut voor Geschiedenis is verantwoordelijk voor het leeuwendeel van het historisch onderzoek dat aan de Universiteit Leiden wordt uitgevoerd.

Het belangrijk tijdig te bedenken in welke werkomgeving je stage zou willen lopen, zodat je minstens een half jaar voor aanvang van de stage kunt beginnen met solliciteren.

Het doel van Paul Gobées project is het bevorderen van het gebruik en het delen van open leermaterialen, Open Educational Resources (OER).

Mocht je nog meer verdieping willen na de Academische Pabo, volg dan een masteropleiding. Dat kan aansluitend op je bachelor, maar ook op een later moment - al dan niet in combinatie met een baan.

LIACS is a partner in the EU Erasmus+ Curriculum Development for the Asian education system. The knowledge available in the field of Data Science and Artificial Intelligence education will be shared and adapted for the Asian market.

Binnen de masteropleiding Education and Child Studies kun je verschillende typen stages lopen.

The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.

Does a mid-season fire impact invertebrate populations?

Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.