We simuleren interstellaire wolken met speciale plasma-expansies en chemische reacties op ijzige stofdeeltjes in ultrahoogvacuümopstellingen. Dit levert gegevens die nodig zijn om astronomische waarnemingen te interpreteren en de reactienetwerken in de ruimte te modelleren.

Commerciële bedrijven die gebruik willen maken van de expertise en faciliteiten worden doorverwezen naar LAB , de commerciële eenheid die verantwoordelijk is voor gespecialiseerd laboratoriumwerk.

Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.

Stars and planets form within cold, dense clouds of gas and dust drifting through interstellar space. Although dust makes up only a small fraction of this material, it plays a key role in shaping the chemical evolution of these environments.

The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.

In this thesis, we present new laboratory data of interstellar dust analogues.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).

Promotor: Prof.dr. H.V.J. Linnartz

Promotor: Prof.dr. H.L.V. Linnartz

Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

Promotor: H.V.J. Linnartz

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

Promotores: P.G.L. Klinkhamer, P.M. Brakefield, Co-Promotor: M. Bruinsma

Lezing

Contact information and visitor's address

Een belangrijke uitdaging in de neurowetenschappen is het begrijpen hoe neuronen in honderden onderling verbonden hersengebieden sensorische input integreren met eerdere verwachtingen om bewegingen te initiëren en beslissingen te nemen.

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

Webinar, Q&A, discussion

This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Cognitieve psychologie is de studie van mentale functies, waaronder aandacht, geheugen, bewustzijn, emotie, taal en actiecontrole. Het doel is om de complexe relaties tussen brein, cognitie en gedrag te begrijpen.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

This thesis investigates reactive interfaces in surface science across three domains: heterogeneous catalysis, environmental nanoplastics, and two-dimensional materials.

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.

Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

Promotor: T. H. Oosterkamp

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

Promotie

Promotie

Promotie

De Universiteit Leiden zet zich ervoor in dat haar laboratoria een accreditatie krijgen van het Laboratory Efficiency Assessment Framework (LEAF)