Heeft jouw peuter of kleuter last van verlegen of angstig gedrag? Dan kan onze stapsgewijze (matched-care) behandeling, Brave Steps, jou misschien helpen. Bezoek de website voor meer informatie.

Een stapsgewijze aanpak voor het opbouwen van zelfvertrouwen bij jonge kinderen die angstig zijn.

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

Schuurman onderzoekt hoe Rusland zijn geheime operaties tegen Europese landen laat escaleren.

Promotie

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Dit onderzoek presenteert een vijfstappenplan voor de ontwikkeling van een effectieve gedragsgerichte cyberveiligheidsstrategie.

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

Hydrogen fuel cells are expected to be pivotal in the energetic transition towards renewable energy sources such as solar and wind power. However, their industrial scalability is severely hindered by the high cost and degradation rate of platinum catalysts, one of their key components. Addressing this…

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.

In this thesis, we study different curved single crystals because of the diversity of surface structures across their curvature.

The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

Reinforcement learning is a framework that enables agents to learn in a manner similar to humans, i.e. through trial and error. Ideally, we would like to train a generalist agent capable of performing multiple tasks and achieving various goals.

Heeft jouw peuter of kleuter last van verlegen of angstig gedrag? Dan kan één van onze projecten binnen het Dappere Kleintjes onderzoeksproject jou misschien helpen! Bezoek de website voor meer informatie.

Peter Hoppenbrouwers

This dissertation presents the synthesis and evaluation of antibody recognition for various capsular polysaccharide (CP) fragments of Staphylococcus aureus (S. aureus).

Promotor: Roeland M.H. Merks

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

De huidige elektrochemische theorie voldoet niet voor realistische platina-elektroden. Wetenschappers van de Universiteit Leiden hebben nu voor het eerst de invloed van imperfecte platina-oppervlakken in kaart gebracht. Dat geeft een beter beeld van deze elektroden, met toepassingen voor waterstofproductie…

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

The global agri-food system plays a critical role in food security and environmental issues.

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

Statistical distributions in LCA and converting between different representations of these distributions.

Binnen Dappere Kleintjes werken we aan verschillende projecten om peuters en kleuters te helpen die snel angstig of verlegen zijn. We richten ons op het vroeg herkennen van angstig gedrag én op het ondersteunen van ouders om hier mee om te gaan.

The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

Dissociative chemisorption is an important reaction step in many catalytic reactions.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.

Sheltering is an immediate human need and determines well-being andhealth.

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

Freshwater biodiversity has been threatened by eutrophication due to excessive nutrients in the environment. Releasing the freshwater species from such pressures requires efforts from industry and manufacturers to avoid emissions to vulnerable and high-risk regions.

CMLCA is a software tool that supports the technical steps of the Life Cycle Assessment. The focus of the program is on advanced computational aspects of life cycle inventory calculations.

Promotor: Prof.dr. J.N. Kok

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

During the course of drug discovery translational steps are made.

Promotor: G. J. Kroes

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

This thesis advance our understanding and the application of molecular catalysts relevant to the reduction of oxygen as well as reduction of nitrite.

Achter de schermen werken er veel verschillende mensen mee aan de projecten binnen de Dappere Kleintjes onderzoekslijn. Zie hieronder een overzicht van het onderzoeksteam.

Tijdens het najaarssemester (september-december) biedt het NIMAR een Engelstalige minor die zich richt op de studie van Marokko vanuit sociaalwetenschappelijk en geesteswetenschappelijk perspectief. Het semester onderwijst etnografische onderzoeksvaardigheden in een Marokkaanse omgeving.

Cell-based medicinal products (CBMPs), such as CAR T cells, are highly complex biopharmaceutical products offering various treatment options for serious illnesses such as cancer or autoimmune diseases.