In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

De onderzoeksgroep Corporate Governance en Strategie onderzoekt hoe, met wie en voor wie een onderneming waarde creëert/vastlegt, met als doel de praktijk en beleidsmakers te informeren over kwesties rondom bestuur. De onderzoeksgroep focust zich op het duale karakter van de onderneming. Namelijk als…

Arco Timmermans' handboek brengt experts samen om het vakgebied public affairs, de uitdagingen ervan en de relatie met democratie te verkennen.

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

Dit onderzoek presenteert een vijfstappenplan voor de ontwikkeling van een effectieve gedragsgerichte cyberveiligheidsstrategie.

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

Op 23 juni 2020 verdedigde Santy Kouwagam haar proefschrift 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. C.E. von Benda-Beckmann.

In theory, states can gain security by acquiring internal arms or external allies. Yet the empirical literature offers mixed findings: some studies find arms and allies to be substitutes, while others find them to be complements. Political scientists Matthew Digiuseppe (Leiden University) and Paul Poast…

Om de kwaliteit van ons onderzoek te waarborgen, beoordeelt een commissie van externe experts onze instituten.

Onze medewerkers en studenten maken deel uit van de taskforces van Una Europa. Deze taskforces vertalen de kernthema’s van Una Europa naar concrete acties.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

With the advent of multicore processors and data centers, computer hardware has become increasingly parallel, allowing one to run multiple pieces of software at the same time on different machines. Coordination of these pieces is best expressed in a coordination language as an explicit interaction protocol…

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

Promotor: Prof.dr. M. Ubbink

In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.

What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?

De Una Europa Clusters brengen vooraanstaande deskundigen en ervaren personeelsleden van de talrijke academische en professionele diensten van de Una Europa -partners samen.

De Business Studies Seminar (BUSS) Series biedt seminars van uitgenodigde wetenschappers over organisatorisch, juridisch en technologisch onderzoek. In 2024 zullen de onderzoeksgroepen Organizational and Entrepreneurial Behavior, Technology and Innovation en Corporate Governance and Strategy diverse…

Ons onderwijsaanbod is breed en divers. Hieronder vindt u alle informatie over de vakken die door de afdeling Bedrijfswetenschappen worden verzorgd. Als u op een vak klikt, wordt u doorgeleid naar de studiegids.

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Promotores: J. Jonkers, K.E. de Visser

Large carnivore population is globally declining as a result of the fragmentation of habitat, large prey depletion and retaliatory killing by pastoralists.

'Ik ga het waarschijnlijk hebben over wat er de dag ervoor is gebeurd.'

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

Understanding DNA repair mechanisms is essential for advancing plant biotechnology and crop improvement. This study investigates how double-strand breaks (DSBs), induced by CRISPR/Cas systems, are repaired in the model plant Arabidopsis thaliana, and how these processes influence Agrobacterium tumefaciens…

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.