1,886 zoekresultaten voor “modelling simulations” in de Publieke website
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Nieuwe publicatie van Christa Tobler over alternatieve modellen van EU-integratie
Na de conferentie van de 20e Oostenrijkse Dag van het Europees recht in september 2021 aan de Universiteit van Liechtenstein in Vaduz, zijn de academische papers van de conferentie nu in boekvorm gepubliceerd. Tot de bijdragen aan het boek behoort een hoofdstuk van Christa Tobler: Christa Tobler, ‘Finally…
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Zsuzsa Bakk
Faculteit der Sociale Wetenschappen
z.bakk@fsw.leidenuniv.nl | +31 71 527 8032
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Tales Yamamoto
Wiskunde en Natuurwetenschappen
t.m.yamamoto@cml.leidenuniv.nl | +31 71 527 2727
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Roy de Kleijn
Faculteit der Sociale Wetenschappen
kleijnrde@fsw.leidenuniv.nl | +31 71 527 3915
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Sterrewacht Leiden
Sterrewacht Leiden is het sterrenkundig instituut van de Faculteit der Wiskunde en Natuurwetenschappen van de Universiteit Leiden.
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Photoinduced processes in dye-sensitized photoanodes under the spotlight: a multiscale in silico investigation
With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…
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Een stuk heelal in de computer
Simulaties van sterrenstelsels helpen om astronomische waarnemingen beter te begrijpen. De EAGLE simulatie, een groot project waarin Leidse astronomen een hoofdrol hebben, laat de evolutie van het heelal zien, van vlak na de Oerknal tot nu.
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Handbook of Signal Processing Systems
Handbook of Signal Processing Systems is organized in four parts. The first part motivates representative applications that drive and apply state-of-the art methods for design and implementation of signal processing systems; the second part discusses architectures for implementing these applications;…
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Galaxy formation and the structure of the Universe
Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)
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The integration of meta-analysis and classification & regression trees: meta-CART
In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).
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Database vol 3D-modellen: ‘Misschien helpt het ons inclusiever met restitutie om te gaan’
Computers van wetenschappers staan inmiddels vol met ingewikkelde 3D-modellen, maar voor de uitwisseling van de gegevens is nog geen standaard ontwikkeld. Een nieuwe database moet daar verandering in brengen. Buitenpromovendus Liselore Tissen ontvangt een beurs om er namens Universiteit Leiden (en TU…
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Advances in Survival Analysis and Optimal Scaling Methods
This thesis is based on five papers on several topics.
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Inverse design of curvature-sensing antiviral peptides
Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.
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Software development by abstract behavioural specification
The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.
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Leiden University wins best position paper at the 2019 Model ICAO
The 2019 Model ICAO took place from 21-24 May at the ICAO headquarters in Montreal.
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MULTIPLY - MULTIscale SENTINEL land surface information retrieval Platform
Aim: To develop and enable application of a practical, flexible, user-friendly platform to provide the scientific community with a tool to generate land surface products and its associated uncertainties and exploit these for data-intensive science.
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Global fitness maximising approaches to evaluate the trade-offs involved in the evergreen and deciduous conundrum
Which traits and/or trade-offs determine benefits of being deciduous or evergreen?
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Interactions from lipid membrane deformations
Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Non-Abelian metamaterials: emergent computing and memory
In the traditional theory of linear elasticity, superposition dictates that the response of a material does not depend on the sequence of the applied mechanical actuations.
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Two-photon luminescence of gold nanorods: applications to single-particle tracking and spectroscopy
Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.
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Evolutionary molecular dynamics
This thesis introduces the concept of
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Stochastic resetting and hierarchical synchronisation
Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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Actors at work
Promotor: F.S. de Boer Co-promotor: P. T. de Gouw
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NMR studies of protein-small molecule and protein-peptide interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Anyonic, cosmic, and chaotic: three faces of Majorana fermions
In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…
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Improving vegetation representation in Multi-sensor Earth Observation Products through phenology and trait-based priors
What are the behaviours of plant traits throughout various points in the growing season in a radiative transfer model framework and how well can this knowledge be integrated through data assimilation to provide priors for robust local and global vegetation products and analysis?
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Ga mee op zoek naar het geheim van ‘Marokkaanse model’ : Studiereis islam, gender, en burgerschap
Marokko is een van de weinige landen in Noord-Afrika die aan de Arabische lente een vreedzame vorm heeft weten te geven door het pad van brede, gestage politieke hervormingen op te gaan. De Marokkaanse overheid verklaart de relatieve maatschappelijke rust daarnaast ook door haar islampolitiek, gericht…
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extragalactic gas: predicting properties and detection with the EAGLE simulations
Promotie
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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Blowup in the complex Ginzburg-Landau equation
Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer
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Bouwen aan de quantumtoekomst op een gewone computer
Computerwetenschapper Tim Coopmans gebruikt pen, papier en gewone computers om de best mogelijke quantumcomputer te simuleren. Hij vertelt over zijn onderzoek en hoe dit helpt om een bruikbare quantumcomputer sneller werkelijkheid te maken. ‘Ik hoop dat ik zal meemaken dat quantumcomputers echt iets…
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G-zips and Ekedahl-Oort strata for Hodge type Shimura varieties
Promotores: S.J. Edixhoven, F. Andreatta
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Probing Cosmic Monsters: Confronting Hydrodynamic Simulations with New Observations of High-density Environments
Promotie
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Withstanding the cold: energy feedback in simulations of galaxies that include a cold interstellar medium
Promotie
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Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: M. Danhof, Co-promotor: E.C.M. de Lange
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Tessa Verhoef
Wiskunde en Natuurwetenschappen
t.verhoef@liacs.leidenuniv.nl | +31 71 527 7903
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Ramira van der Meulen
Wiskunde en Natuurwetenschappen
a.van.der.meulen@liacs.leidenuniv.nl | +31 71 527 2727
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Mirko Forastiere
Wiskunde en Natuurwetenschappen
m.forastiere@cml.leidenuniv.nl | +31 71 527 2727
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Sebastiaan Deetman
Wiskunde en Natuurwetenschappen
s.p.deetman@cml.leidenuniv.nl | +31 71 527 5616
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Ruben Huele
Wiskunde en Natuurwetenschappen
huele@cml.leidenuniv.nl | +31 71 527 FLEX
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Anisotropy, multivalency and flexibility-induced effects in colloidal systems
We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.
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Stellar radio beacons for Galactic astrometry
A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Molecules during stellar formation and death
Promotor: Prof.dr. E. F. van Dishoeck